(Q42123271)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25821590%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

title

Blockade of vascular endothelial growth factor receptor 1 prevents inflammation and vascular leakage in diabetic retinopathy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25821590%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

0 references

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25821590%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Hu Huang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25821590%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

author name string

Jianbo He

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25821590%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Hong Wang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25821590%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Ying Liu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25821590%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Wen Li

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25821590%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

publication date

3 March 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25821590%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

published in

Journal of Ophthalmology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25821590%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

volume

2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25821590%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

page(s)

605946

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25821590%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 3.0 Unported

4 March 2020

copyright license

start time

1 January 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

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1 reference

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VEGF receptor blockade markedly reduces retinal microglia/macrophage infiltration into laser-induced CNV.

29 May 2018

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The role of arginase I in diabetes-induced retinal vascular dysfunction in mouse and rat models of diabetes

29 May 2018

1 reference

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Targeted deletion of Vegfa in adult mice induces vision loss

29 May 2018

1 reference

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Elevated vascular endothelial growth factor receptor-2 abundance contributes to increased angiogenesis in vascular endothelial growth factor receptor-1-deficient mice

29 May 2018

1 reference

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Global prevalence and major risk factors of diabetic retinopathy

29 May 2018

1 reference

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Reduced retinal neovascularization, vascular permeability, and apoptosis in ischemic retinopathy in the absence of prolyl hydroxylase-1 due to the prevention of hyperoxia-induced vascular obliteration

29 May 2018

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Blockade of VEGFR1 and 2 suppresses pathological angiogenesis and vascular leakage in the eye

29 May 2018

1 reference

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TNFalpha is required for late BRB breakdown in diabetic retinopathy, and its inhibition prevents leukostasis and protects vessels and neurons from apoptosis

29 May 2018

1 reference

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Temporal requirement of RPE-derived VEGF in the development of choroidal vasculature

29 May 2018

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Global estimates of the prevalence of diabetes for 2010 and 2030

29 May 2018

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Activation of the Wnt pathway plays a pathogenic role in diabetic retinopathy in humans and animal models

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4363713

Activation of PKC-delta and SHP-1 by hyperglycemia causes vascular cell apoptosis and diabetic retinopathy

29 May 2018

1 reference

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Accuracy and precision in quantitative fluorescence microscopy

29 May 2018

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The transforming growth factor-beta pathway is a common target of drugs that prevent experimental diabetic retinopathy

29 May 2018

1 reference

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FOXO1 plays an important role in enhanced microvascular cell apoptosis and microvascular cell loss in type 1 and type 2 diabetic rats

29 May 2018

1 reference

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FLT1 and its ligands VEGFB and PlGF: drug targets for anti-angiogenic therapy?

29 May 2018

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Endogenous VEGF is required for visual function: evidence for a survival role on müller cells and photoreceptors

29 May 2018

1 reference

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Role of NADPH oxidase in retinal vascular inflammation.

29 May 2018

1 reference

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Inducible nitric oxide synthase isoform is a key mediator of leukostasis and blood-retinal barrier breakdown in diabetic retinopathy

29 May 2018

1 reference

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Interaction between NO and COX pathways in retinal cells exposed to elevated glucose and retina of diabetic rats

29 May 2018

1 reference

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Selective stimulation of VEGFR-1 prevents oxygen-induced retinal vascular degeneration in retinopathy of prematurity

29 May 2018

1 reference

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Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1.

29 May 2018

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Activation of nuclear factor-kappaB induced by diabetes and high glucose regulates a proapoptotic program in retinal pericytes

29 May 2018

1 reference

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Immunolocalisation of the VEGF receptors FLT-1, KDR, and FLT-4 in diabetic retinopathy

29 May 2018

1 reference

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Upregulation of the vascular endothelial growth factor/vascular endothelial growth factor receptor system in experimental background diabetic retinopathy of the rat.

29 May 2018

1 reference

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Vascular endothelial growth factor is a secreted angiogenic mitogen

29 May 2018

1 reference

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29 May 2018

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Microglial VEGF receptor response is an integral chemotactic component in Alzheimer's disease pathology.

17 August 2018

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Aldose reductase deficiency prevents diabetes-induced blood-retinal barrier breakdown, apoptosis, and glial reactivation in the retina of db/db mice.

17 August 2018

1 reference

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Suppression of ocular neovascularization with siRNA targeting VEGF receptor 1.

17 August 2018

1 reference

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Altered expression patterns of VEGF receptors in human diabetic retina and in experimental VEGF-induced retinopathy in monkey.

17 August 2018

1 reference

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Increased hemangioblast commitment, not vascular disorganization, is the primary defect in flt-1 knock-out mice.

17 August 2018

1 reference

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17 August 2018

1 reference

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Further Pharmacological and Genetic Evidence for the Efficacy of PlGF Inhibition in Cancer and Eye Disease

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2015%2F605946

Vascular endothelial growth factor-induced retinal permeability is mediated by protein kinase C in vivo and suppressed by an orally effective beta-isoform-selective inhibitor

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25821590

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Vascular permeability factor, an endothelial cell mitogen related to PDGF

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25821590

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1155/2015/605946

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25821590%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25821590%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25821590%20AND%20SRC:MED&resulttype=core&format=json