(Q42140470)

English

Investigating inner-sphere reorganization via secondary kinetic isotope effects in the C-H cleavage reaction catalyzed by soybean lipoxygenase: tunneling in the substrate backbone as well as the transferred hydrogen

scientific article published on 30 December 2010

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Investigating inner-sphere reorganization via secondary kinetic isotope effects in the C-H cleavage reaction catalyzed by soybean lipoxygenase: tunneling in the substrate backbone as well as the transferred hydrogen (English)

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

author name string

Matthew P Meyer

1

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Judith P Klinman

2

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

language of work or name

0 references

publication date

30 December 2010

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Journal of the American Chemical Society

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

133

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

3

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

430-439

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

Experimental evidence for heavy-atom tunneling in the ring-opening of cyclopropylcarbinyl radical from intramolecular 12C/13C kinetic isotope effects.

1 reference

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Modular behavior of tauD provides insight into the origin of specificity in alpha-ketoglutarate-dependent nonheme iron oxygenases

1 reference

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29 May 2018

Synthesis of linoleic acids combinatorially-labeled at the vinylic positions as substrates for lipoxygenases

1 reference

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29 May 2018

Experimental evidence for enzyme-enhanced coupled motion/quantum mechanical hydrogen tunneling by ketosteroid isomerase

1 reference

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29 May 2018

Enzyme structure and dynamics affect hydrogen tunneling: The impact of a remote side chain (I553) in soybean lipoxygenase-1

1 reference

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29 May 2018

Tunneling and dynamics in enzymatic hydride transfer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090704

29 May 2018

Quantum catalysis in B12-dependent methylmalonyl-CoA mutase: experimental and computational insights

1 reference

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29 May 2018

Linking protein structure and dynamics to catalysis: the role of hydrogen tunnelling.

1 reference

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29 May 2018

Intrinsic isotope effects on benzylic hydroxylation by the aromatic amino acid hydroxylases: evidence for hydrogen tunneling, coupled motion, and similar reactivities

1 reference

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29 May 2018

Catalysis of electron transfer during activation of O2 by the flavoprotein glucose oxidase

1 reference

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29 May 2018

Temperature-dependent isotope effects in soybean lipoxygenase-1: correlating hydrogen tunneling with protein dynamics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090704

29 May 2018

Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1

1 reference

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29 May 2018

Synthesis and biological activities of novel antiallergic agents with 5-lipoxygenase inhibiting action

1 reference

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29 May 2018

Nature of hydrogen transfer in soybean lipoxygenase 1: separation of primary and secondary isotope effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090704

29 May 2018

Enzyme dynamics and hydrogen tunnelling in a thermophilic alcohol dehydrogenase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090704

29 May 2018

15-Lipoxygenase and its inhibition: a novel therapeutic target for vascular disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090704

29 May 2018

Expression of 15-lipoxygenase by human colorectal carcinoma Caco-2 cells during apoptosis and cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090704

29 May 2018

A link between protein structure and enzyme catalyzed hydrogen tunneling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090704

29 May 2018

Unmasking of hydrogen tunneling in the horse liver alcohol dehydrogenase reaction by site-directed mutagenesis

1 reference

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29 May 2018

12-Lipoxygenase, 12(S)-HETE, and cancer metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090704

29 May 2018

The expression of isotope effects on enzyme-catalyzed reactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090704

29 May 2018

Hydrogen tunneling in enzyme reactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090704

29 May 2018

Calculations predict a large inverse H/D kinetic isotope effect on the rate of tunneling in the ring opening of cyclopropylcarbinyl radical

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090704

17 August 2018

Evidence for protein radical-mediated nuclear tunneling in fatty acid alpha-oxygenase

1 reference

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17 August 2018

Proton-coupled electron transfer in soybean lipoxygenase

1 reference

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17 August 2018

Deuterium Isotope Effects on Hydrophobic Interactions: The Importance of Dispersion Interactions in the Hydrophobic Phase

1 reference

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17 August 2018

Is Hydrogen Tunneling Involved in AcylCoA Desaturase Reactions? The Case of a Delta(9) Desaturase That Transforms (E)-11-Tetradecenoic Acid into (Z,E)-9,11-Tetradecadienoic Acid This work was supported by Comisión Asesora de Investigación Científica

1 reference

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17 August 2018

Large Kinetic Isotope Effects in Methane Oxidation Catalyzed by Methane Monooxygenase: Evidence for C−H Bond Cleavage in a Reaction Cycle Intermediate†

1 reference

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1 December 2018

Unmasking of Deuterium Kinetic Isotope Effects on the Methane Monooxygenase Compound Q Reaction by Site-Directed Mutagenesis of Component B

1 reference

https://pubmed.ncbi.nlm.nih.gov/21192631

12 December 2020

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Identifiers

10.1021/JA1050742

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 October 2017

ResearchGate publication ID

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