(Q42165194)

17 October 2017

Oncogenic KRAS activates hedgehog signaling pathway in pancreatic cancer cells (English)

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17 October 2017

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Zhenyu Ji

1

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17 October 2017

Fang C Mei

series ordinal

2

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17 October 2017

Jingwu Xie

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3

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17 October 2017

Xiaodong Cheng

series ordinal

4

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17 October 2017

language of work or name

English

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publication date

12 March 2007

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Journal of Biological Chemistry

17 October 2017

8

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based on heuristic

inferred from page(s)

published in

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17 October 2017

282

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17 October 2017

14048-14055

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17 October 2017

19

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Genetic progression and divergence in pancreatic carcinoma

17 October 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

Allelic loss is often the first hit in the biallelic inactivation of the p53 and DPC4 genes during pancreatic carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

Analysis of K-ras gene mutation in hyperplastic duct cells of the pancreas without pancreatic disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M611089200

Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

Indian hedgehog signaling pathway: expression and regulation in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

Hedgehog signaling in animal development: paradigms and principles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

The Hedgehog response network: sensors, switches, and routers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

Hedgehog/Ras interactions regulate early stages of pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

BRAFE600-associated senescence-like cell cycle arrest of human naevi

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

Activation of antioxidant pathways in ras-mediated oncogenic transformation of human surface ovarian epithelial cells revealed by functional proteomics and mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

RAS-mediated epigenetic inactivation of OPCML in oncogenic transformation of human ovarian surface epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

Immortal human pancreatic duct epithelial cell lines with near normal genotype and phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

In vitro modeling of human pancreatic duct epithelial cell transformation defines gene expression changes induced by K-ras oncogenic activation in pancreatic carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

Selective inhibition of Ras-dependent cell growth by farnesylthiosalisylic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

Novel Ras antagonist blocks human melanoma growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

GLI transcription factors: mediators of oncogenic Hedgehog signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

Pancreatic cancer cell radiation survival and prenyltransferase inhibition: the role of K-Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

Regulation of Gli1 localization by the cAMP/protein kinase A signaling axis through a site near the nuclear localization signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

Hedgehog signaling and congenital malformations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

A role of PDGFRalpha in basal cell carcinoma proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

Phosphoinositide 3-kinase and Akt are essential for Sonic Hedgehog signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

Protein kinase C-delta and mitogen-activated protein/extracellular signal-regulated kinase-1 control GLI activation in hedgehog signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

A new functional Ras antagonist inhibits human pancreatic tumor growth in nude mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611089200

21 January 2018

Identifiers

DOI

10.1074/JBC.M611089200

1 reference

17 October 2017

1 reference