(Q42170401)

17 October 2017

Self-antigen recognition by TGF beta1-deficient T cells causes their activation and systemic inflammation (English)

1 reference

17 October 2017

Ramireddy Bommireddy

1

1 reference

17 October 2017

Leena J Pathak

2

1 reference

17 October 2017

Jennifer Martin

3

1 reference

17 October 2017

Ilona Ormsby

4

1 reference

17 October 2017

Sandra J Engle

5

1 reference

17 October 2017

Gregory P Boivin

6

1 reference

17 October 2017

George F Babcock

7

1 reference

17 October 2017

Anna U Eriksson

8

1 reference

17 October 2017

Ram R Singh

9

1 reference

17 October 2017

Thomas Doetschman

10

1 reference

17 October 2017

24 July 2006

1 reference

17 October 2017

Laboratory Investigation

1 reference

17 October 2017

86

1 reference

17 October 2017

10

1 reference

17 October 2017

1008-1019

1 reference

https://scigraph.springernature.com/pub.10.1038/labinvest.3700460

17 October 2017

0 references

cites work

Elimination of both CD4+ and CD8+ T cells but not B cells eliminates inflammation and prolongs the survival of TGFbeta1-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291532

TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291532

Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291532

CD28 disruption exacerbates inflammation in Tgf-beta1-/- mice: in vivo suppression by CD4+CD25+ regulatory T cells independent of autocrine TGF-beta1.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291532

Expression of dual TCR on DO11.10 T cells allows for ovalbumin-induced oral tolerance to prevent T cell-mediated colitis directed against unrelated enteric bacterial antigens

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291532

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291532

Transforming growth factor beta blocks Tec kinase phosphorylation, Ca2+ influx, and NFATc translocation causing inhibition of T cell differentiation

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291532

TGF beta 1 inhibits Ca2+-calcineurin-mediated activation in thymocytes

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291532

TGF-beta1 mediates the hypertrophic cardiomyocyte growth induced by angiotensin II.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291532

Requirement for transforming growth factor beta1 in controlling T cell apoptosis

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291532

Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291532

Transforming growth factor beta1 suppresses nonmetastatic colon cancer at an early stage of tumorigenesis

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291532

Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291532

Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291532

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291532

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291532

Smad3 mutant mice develop metastatic colorectal cancer

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291532

Onset and progression of pathological lesions in transforming growth factor-beta 1-deficient mice.

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291532

MHC-independent genetic regulation of liver damage in a mouse model of autoimmune hepatocellular injury

29 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291532

TGF-β1 Regulates Lymphocyte Homeostasis by Preventing Activation and Subsequent Apoptosis of Peripheral Lymphocytes

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291532

Elimination of colon cancer in germ-free transforming growth factor beta 1-deficient mice

17 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16865088

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Germ-free and barrier-raised TGF beta 1-deficient mice have similar inflammatory lesions

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16865088

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/LABINVEST.3700460

1 reference

17 October 2017

1 reference

17 October 2017

PubMed publication ID

16865088

1 reference