(Q42171505)

English

SB-649915-B, a novel 5-HT1A/B autoreceptor antagonist and serotonin reuptake inhibitor, is anxiolytic and displays fast onset activity in the rat high light social interaction test

scientific article published on 14 March 2007

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

17 October 2017

SB-649915-B, a novel 5-HT1A/B autoreceptor antagonist and serotonin reuptake inhibitor, is anxiolytic and displays fast onset activity in the rat high light social interaction test (English)

1 reference

Europe PubMed Central

PubMed publication ID

17 October 2017

0 references

social interaction

1 reference

based on heuristic

inferred from title

author name string

Kathryn R Starr

1

1 reference

Europe PubMed Central

PubMed publication ID

17 October 2017

Gary W Price

2

1 reference

Europe PubMed Central

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17 October 2017

Jeannette M Watson

3

1 reference

Europe PubMed Central

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17 October 2017

Peter J Atkinson

4

1 reference

Europe PubMed Central

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17 October 2017

Roberto Arban

5

1 reference

Europe PubMed Central

PubMed publication ID

17 October 2017

Sergio Melotto

6

1 reference

Europe PubMed Central

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17 October 2017

Lee A Dawson

7

1 reference

Europe PubMed Central

PubMed publication ID

17 October 2017

Jim J Hagan

8

1 reference

Europe PubMed Central

PubMed publication ID

17 October 2017

Neil Upton

9

1 reference

Europe PubMed Central

PubMed publication ID

17 October 2017

Mark S Duxon

10

1 reference

Europe PubMed Central

PubMed publication ID

17 October 2017

language of work or name

0 references

publication date

14 March 2007

1 reference

Europe PubMed Central

PubMed publication ID

17 October 2017

Neuropsychopharmacology

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Europe PubMed Central

PubMed publication ID

17 October 2017

32

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Europe PubMed Central

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17 October 2017

10

1 reference

Europe PubMed Central

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17 October 2017

2163-2172

1 reference

Europe PubMed Central

PubMed publication ID

17 October 2017

Modulation of 5-HT release in the guinea-pig brain following long-term administration of antidepressant drugs

1 reference

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Zacopride: anxiolytic profile in rodent and primate models of anxiety

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Can social interaction be used to measure anxiety?

1 reference

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21 January 2018

Interaction between a selective 5-HT1A receptor antagonist and an SSRI in vivo: effects on 5-HT cell firing and extracellular 5-HT

1 reference

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21 January 2018

Serotonin and hippocampal neurogenesis

1 reference

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21 January 2018

Repeated administration of the 5-HT(1B) receptor antagonist SB-224289 blocks the desensitisation of 5-HT(1B) autoreceptors induced by fluoxetine in rat frontal cortex

1 reference

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21 January 2018

Serotonergic responsivity in obsessive-compulsive disorder. Effects of chronic clomipramine treatment

1 reference

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21 January 2018

5-HT and antidepressants: new views from microdialysis studies

1 reference

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7 January 2021

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Pindolol Induces a Rapid Improvement of Depressed Patients Treated With Serotonin Reuptake Inhibitors

1 reference

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3,4-Dihydro-2H-benzoxazinones are 5-HT(1A) receptor antagonists with potent 5-HT reuptake inhibitory activity.

1 reference

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Effectiveness of pindolol plus serotonin uptake inhibitors in depression: a meta-analysis of early and late outcomes from randomised controlled trials

1 reference

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7 January 2021

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The use of pindolol with fluoxetine in the treatment of major depression: final results from a double-blind, placebo-controlled trial

1 reference

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7 January 2021

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Effect of pindolol in hastening response to fluoxetine in the treatment of major depression: a double-blind, placebo-controlled trial

1 reference

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7 January 2021

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Behavioral, neuroendocrine and serotonergic consequences of single social defeat and repeated fluoxetine pretreatment in the Lewis rat strain.

1 reference

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7 January 2021

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Effectiveness of Pindolol With Selected Antidepressant Drugs in the Treatment of Major Depression

1 reference

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7 January 2021

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Effect of pindolol on onset of action of paroxetine in the treatment of major depression: intermediate analysis of a double-blind, placebo-controlled trial. Réseau de Recherche et d'Expérimentation Psychopharmacologique

1 reference

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7 January 2021

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Do animal models of anxiety predict anxiolytic-like effects of antidepressants?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

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Modulation of dopamine release in the nucleus accumbens by 5-HT1B agonists: involvement of the hippocampo-accumbens pathway

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence for accelerated desensitisation of 5-HT(2C) receptors following combined treatment with fluoxetine and the 5-HT(1A) receptor antagonist, WAY 100,635, in the rat

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

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Effects of 5-HT1A receptor antagonists on fluoxetine-induced changes in extracellular serotonin concentrations in rat frontal cortex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

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The role of 5-HT(1A) and 5-HT(1B/1D) receptors on the modulation of acute fluoxetine-induced changes in extracellular 5-HT: the mechanism of action of (+/-)pindolol

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of chronic fluoxetine and WAY-100635 treatment on serotonergic neurotransmission in the frontal cortex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Enhancement of fluoxetine-dependent increase of extracellular serotonin (5-HT) levels by (-)-pindolol, an antagonist at 5-HT1A receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Depression: a case of neuronal life and death?

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Latency to paroxetine-induced anxiolysis in the rat is reduced by co-administration of the 5-HT(1A) receptor antagonist WAY100635.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

The use of social interaction as a method for detecting anxiolytic activity of chlordiazepoxide-like drugs

1 reference

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7 January 2021

based on heuristic

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A test of anxiety that distinguishes between the actions of benzodiazepines and those of other minor tranquilisers and of stimulants

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Electrophysiological, biochemical, neurohormonal and behavioural studies with WAY-100635, a potent, selective and silent 5-HT1A receptor antagonist

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

A pharmacological profile of the selective silent 5-HT1A receptor antagonist, WAY-100635

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Distress vocalization in rat pups. A simple screening method for anxiolytic drugs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

The ability of WAY100,635 to potentiate the neurochemical and functional actions of fluoxetine is enhanced by co-administration of SB224,289, but not BRL15572

1 reference

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7 January 2021

based on heuristic

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Differential modulation of antipredator defensive behavior in Swiss-Webster mice following acute or chronic administration of imipramine and fluoxetine.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Acute and chronic treatment with 5-HT reuptake inhibitors differentially modulate emotional responses in anxiety models in rodents.

1 reference

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7 January 2021

based on heuristic

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Influence of 5-HT1A receptors on central noradrenergic activity: microdialysis studies using (+/-)-MDL 73005EF and its enantiomers

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Desensitization of 5-HT(1A) autoreceptors by a low chronic fluoxetine dose effect of the concurrent administration of WAY-100635.

1 reference

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7 January 2021

based on heuristic

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(-)-Pindolol, but not buspirone, potentiates the citalopram-induced rise in extracellular 5-hydroxytryptamine

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

5-HT1A autoreceptors and the mode of action of selective serotonin reuptake inhibitors (SSRI)

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence for 5-HT autoreceptor-mediated, nerve impulse-independent, control of 5-HT synthesis in the rat brain

1 reference

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7 January 2021

based on heuristic

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WAY100635-induced augmentation of the 5-HT-elevating action of citalopram: relative importance of the dose of the 5-HT1A (auto)receptor blocker versus that of the 5-HT reuptake inhibitor

1 reference

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7 January 2021

based on heuristic

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Effects of chronic fluoxetine treatment on behavioral and neuroendocrine responses to meta-chlorophenylpiperazine in obsessive-compulsive disorder

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Species differences in the pharmacology of terminal 5-HT autoreceptors in mammalian brain

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Simultaneous blockade of 5-HT1A/B receptors and 5-HT transporters results in acute increases in extracellular 5-HT in both rats and guinea pigs: in vivo characterization of the novel 5-HT1A/B receptor antagonist/5-HT transport inhibitor SB-649915-B.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of chronic administration of selective 5-hydroxytryptamine and noradrenaline uptake inhibitors on a putative index of 5-HT2C/2B receptor function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of RO 60 0175, a 5-HT(2C) receptor agonist, in three animal models of anxiety.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Anxiogenic-like effects of mCPP and TFMPP in animal models are opposed by 5-HT1C receptor antagonists

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

SB 242084, a selective and brain penetrant 5-HT2C receptor antagonist

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Enhancement of cortical and hippocampal cholinergic neurotransmission through 5-HT1A receptor-mediated pathways by BAY x 3702 in freely moving rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Early desensitization of somato-dendritic 5-HT1A autoreceptors in rats treated with fluoxetine or paroxetine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Anxiolytic-like effect of paroxetine in a rat social interaction test

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Pindolol and mianserin augment the antidepressant activity of fluoxetine in hospitalized major depressed patients, including those with treatment resistance.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

The effects of paroxetine given repeatedly on the 5-HT receptor subpopulations in the rat brain.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Pharmacological diversity between native human 5-HT1B and 5-HT1D receptors sited on different neurons and involved in different functions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Pindolol augmentation of antidepressant therapy.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

The serotonergic and noradrenergic systems of the hippocampus: their interactions and the effects of antidepressant treatments

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of WAY-100135 on the hippocampal acetylcholine release potentiated by 8-OH-DPAT, a serotonin1A receptor agonist, in normal and p-chlorophenylalanine-treated rats as measured by in vivo microdialysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Chronic fluoxetine-induced desensitization of 5-HT1A and 5-HT1B autoreceptors: regional differences and effects of WAY-100635.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

The 5-HT1A receptor antagonist (S)-UH-301 decreases dopamine release in the rat nucleus accumbens and striatum

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Ultrasonic vocalizations in rat pups: effects of serotonergic ligands

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

SSRI treatment decreases prolactin and hyperthermic responses to mCPP.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Pindolol augmentation of selective serotonin reuptake inhibitors: PET evidence that the dose used in clinical trials is too low.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

5-HT1A receptor antagonist administration decreases cell proliferation in the dentate gyrus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Enhancement of 5-HT1B and 5-HT1D receptor antagonist effects on extracellular 5-HT levels in the guinea-pig brain following concurrent 5-HT1A or 5-HT re-uptake site blockade

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Combined administration of a 5-hydroxytryptamine (5-HT)1D antagonist and a 5-HT reuptake inhibitor synergistically increases 5-HT release in guinea pig hypothalamus in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of pindolol on the function of pre- and postsynaptic 5-HT1A receptors: in vivo microdialysis and electrophysiological studies in the rat brain.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

The 5-HT1A antagonist WAY-100635 selectively potentiates the presynaptic effects of serotonergic antidepressants in rat brain.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

The potential utility of 5-HT1A receptor antagonists in the treatment of cognitive dysfunction associated with Alzheimer s disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

SB-649915, a novel, potent 5-HT1A and 5-HT1B autoreceptor antagonist and 5-HT re-uptake inhibitor in native tissue.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Pindolol augmentation of selective serotonin reuptake inhibitors: accounting for the variability of results of placebo-controlled double-blind studies in patients with major depression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of a selective 5-HT reuptake inhibitor in combination with 5-HT1A and 5-HT1B receptor antagonists on extracellular 5-HT in rat frontal cortex in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Pindolol potentiation of paroxetine for generalized social phobia: a double-blind, placebo-controlled, crossover study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Biochemical effects of the antidepressant paroxetine, a specific 5-hydroxytryptamine uptake inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of acute and chronic fluoxetine treatment of CRH-induced anxiety.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Anxiogenic effect of central CCK administration is attenuated by chronic fluoxetine or ipsapirone treatment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

SB-243213; a selective 5-HT2C receptor inverse agonist with improved anxiolytic profile: lack of tolerance and withdrawal anxiety

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Chronic treatment with fluvoxamine desensitizes 5-HT2C receptor-mediated hypolocomotion in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

How long should pindolol be associated with paroxetine to improve the antidepressant response?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.NPP.1301341

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.NPP.1301341

1 reference

Europe PubMed Central

PubMed publication ID

17 October 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 October 2017

ResearchGate publication ID

0 references

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