(Q42189881)

English

Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid beta-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): engineering of inhibitors with altered specificities

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid beta-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): engineering of inhibitors with altered specificities (English)

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

Alzheimer's disease

0 references

protein structure

0 references

crystal structure

1 reference

based on heuristic

inferred from title

author name string

Scheidig AJ

1

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

Hynes TR

2

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

Pelletier LA

3

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

Wells JA

4

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

Kossiakoff AA

5

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

publication date

1 September 1997

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

Protein Science

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

6

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

9

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

1806-1824

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

Crystallographic R factor refinement by molecular dynamics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

26 October 2017

Pancreatic trypsin inhibitor. II. Reaction with trypsin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

26 October 2017

Iterative optimization of high-affinity proteases inhibitors using phage display. 1. Plasmin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

26 October 2017

Ecotin is a potent anticoagulant and reversible tight-binding inhibitor of factor Xa.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

26 October 2017

Structural basis of substrate specificity in the serine proteases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

26 October 2017

Potent and Selective Kunitz Domain Inhibitors of Plasma Kallikrein Designed by Phage Display

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

26 October 2017

Thermodynamics and kinetics of single residue replacements in avian ovomucoid third domains: effect on inhibitor interactions with serine proteinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

26 October 2017

Protein inhibitors of proteinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

26 October 2017

Evolution of Proteolytic Enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

26 October 2017

On the size of the active site in proteases. I. Papain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

26 October 2017

Determination of the operational molarity of solutions of bovine α-chymotrypsin, trypsin, thrombin and factor Xa by spectrofluorimetric titration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

26 October 2017

The refinement and the structure of the dimer of alpha-chymotrypsin at 1.67-A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

26 October 2017

Refined 1.2 A crystal structure of the complex formed between subtilisin Carlsberg and the inhibitor eglin c. Molecular structure of eglin and its detailed interaction with subtilisin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

26 October 2017

High efficiency transformation of E. coli by high voltage electroporation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

26 October 2017

Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

26 October 2017

Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

26 October 2017

Functional evolutionary divergence of proteolytic enzymes and their inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

26 October 2017

Biosynthesis, processing, and evolution of bovine pancreatic trypsin inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

26 October 2017

Slow-cooling protocols for crystallographic refinement by simulated annealing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

26 October 2017

Substrate specificity of trypsin investigated by using a genetic selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

26 October 2017

Current approaches to macromolecular crystallization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

26 October 2017

X-ray crystal structure of the protease inhibitor domain of Alzheimer's amyloid beta-protein precursor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

26 October 2017

Efficient site-directed mutagenesis using uracil-containing DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

26 October 2017

Selecting high-affinity binding proteins by monovalent phage display

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

26 October 2017

Directed evolution of a protein: selection of potent neutrophil elastase inhibitors displayed on M13 fusion phage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

26 October 2017

The refined crystal structure of bovine beta-trypsin at 1.8 A resolution. I. Crystallization, data collection and application of patterson search technique

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

26 October 2017

The Protein Data Bank: a computer-based archival file for macromolecular structures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

26 October 2017

The active centers of Streptomyces griseus protease 3, alpha-chymotrypsin, and elastase: enzyme-substrate interactions close to the scissile bond

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

26 October 2017

DNA sequencing with chain-terminating inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

26 October 2017

A family of protein-cutting proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

29 May 2018

A model for the association of bovine pancreatic trypsin inhibitor with chymotrypsin and trypsin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

29 May 2018

High-level secretion of human growth hormone by Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

29 May 2018

A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

29 May 2018

Converting trypsin to chymotrypsin: the role of surface loops

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

29 May 2018

Structural and functional integrity of specificity and catalytic sites of trypsin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

29 May 2018

On the computation of the fast rotation function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

17 August 2018

Alanine point-mutations in the reactive region of bovine pancreatic trypsin inhibitor: effects on the kinetics and thermodynamics of binding to beta-trypsin and alpha-chymotrypsin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

17 August 2018

Structure of the complex formed by bovine trypsin and bovine pancreatic trypsin inhibitor. II. Crystallographic refinement at 1.9 A resolution.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

17 August 2018

Enzyme specificity of proteinase inhibitor region in amyloid precursor protein of Alzheimer's disease: different properties compared with protease nexin I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143802

17 August 2018

Plastic adaptation toward mutations in proteins: structural comparison of thymidylate synthases

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560060902

21 January 2018

Specificity of alpha-chymotrypsin. Dipeptide substrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/9300481

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Converting trypsin to chymotrypsin: residue 172 is a substrate specificity determinant

1 reference

https://pubmed.ncbi.nlm.nih.gov/9300481

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chromatography of trypsin and its derivatives. Characterization of a new active form of bovine trypsin

1 reference

https://pubmed.ncbi.nlm.nih.gov/9300481

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of amino acid side-chains to S1 cavities of serine proteinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/9300481

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High level expression, purification, and characterization of the Kunitz-type protease inhibitor domain of protease nexin-2/amyloid beta-protein precursor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9300481

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereochemically restrained refinement of macromolecular structures

1 reference

https://pubmed.ncbi.nlm.nih.gov/9300481

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/PRO.5560060902

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q42189881&oldid=1935691283"