(Q42200449)

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Mice with an induced mutation in collagen 8A2 develop larger eyes and are resistant to retinal ganglion cell damage in an experimental glaucoma model.

scientific article published on May 2012

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5 February 2020

Mice with an induced mutation in collagen 8A2 develop larger eyes and are resistant to retinal ganglion cell damage in an experimental glaucoma model (English)

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5 February 2020

retinal ganglion cell

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Matthew R Steinhart

1

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5 February 2020

Frances E Cone

2

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5 February 2020

Cathy Nguyen

3

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5 February 2020

Thao D Nguyen

4

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5 February 2020

Mary E Pease

5

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5 February 2020

Oliver Puk

6

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5 February 2020

Jochen Graw

7

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5 February 2020

Ericka N Oglesby

8

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5 February 2020

Harry A Quigley

9

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5 February 2020

publication date

1 May 2012

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5 February 2020

Molecular Vision

1 reference

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5 February 2020

18

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5 February 2020

1093-1106

1 reference

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5 February 2020

The effects of anesthesia, mouse strain and age on intraocular pressure and an improved murine model of experimental glaucoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

Biomechanics of the human posterior sclera: age- and glaucoma-related changes measured using inflation testing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

An alpha 2 collagen VIII transgenic knock-in mouse model of Fuchs endothelial corneal dystrophy shows early endothelial cell unfolded protein response and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

Biomechanical changes in the sclera of monkey eyes exposed to chronic IOP elevations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

Distribution of COL8A2 and COL8A1 gene variants in Caucasian primary open angle glaucoma patients with thin central corneal thickness.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

A semiautomated targeted sampling method to assess optic nerve axonal loss in a rat model of glaucoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

The in vitro inflation response of mouse sclera.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

Calibration of the TonoLab tonometer in mice with spontaneous or experimental glaucoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

Optic neuropathy due to microbead-induced elevated intraocular pressure in the mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

Changes in the biomechanical response of the optic nerve head in early experimental glaucoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

VAV2 and VAV3 as candidate disease genes for spontaneous glaucoma in mice and humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

The microbead occlusion model: a paradigm for induced ocular hypertension in rats and mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

Laser-induced ocular hypertension in albino CD-1 mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

The morphology and spatial arrangement of astrocytes in the optic nerve head of the mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

Mouse models of retinal ganglion cell death and glaucoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

The genetics of primary open-angle glaucoma: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

Estimation of ocular rigidity based on measurement of pulse amplitude using pneumotonometry and fundus pulse using laser interferometry in glaucoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

Transgenic mice expressing the Tyr437His mutant of human myocilin protein develop glaucoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

Non-invasive biometric assessment of ocular rigidity in glaucoma patients and controls.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

Risk factors and open-angle glaucoma: classification and application

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

Tumor necrosis factor-alpha mediates oligodendrocyte death and delayed retinal ganglion cell loss in a mouse model of glaucoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

The number of people with glaucoma worldwide in 2010 and 2020

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

Targeted disruption of Col8a1 and Col8a2 genes in mice leads to anterior segment abnormalities in the eye

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

Inheritance of a novel COL8A2 mutation defines a distinct early-onset subtype of fuchs corneal dystrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

A mouse model of elevated intraocular pressure: retina and optic nerve findings

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

Laser-induced mouse model of chronic ocular hypertension.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

Experimental Mouse Ocular Hypertension: Establishment of the Model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

Reduction of intraocular pressure and glaucoma progression: results from the Early Manifest Glaucoma Trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

Translimbal laser photocoagulation to the trabecular meshwork as a model of glaucoma in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

Missense mutations in COL8A2, the gene encoding the alpha2 chain of type VIII collagen, cause two forms of corneal endothelial dystrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

Intraocular pressure in genetically distinct mice: an update and strain survey

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

The alpha1(VIII) and alpha2(VIII) collagen chains form two distinct homotrimeric proteins in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

Type VIII collagen has a restricted distribution in specialized extracellular matrices

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

The relation between glaucomatous damage and optic nerve head mechanical compliance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

Type VIII collagen in murine development. Association with capillary formation in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

Characterization of the collagen in the hexagonal lattice of Descemet's membrane: its relation to type VIII collagen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

26 October 2017

The cloning and sequencing of alpha 1(VIII) collagen cDNAs demonstrate that type VIII collagen is a short chain collagen and contains triple-helical and carboxyl-terminal non-triple-helical domains similar to those of type X collagen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

29 May 2018

Optic nerve head extracellular matrix in primary optic atrophy and experimental glaucoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

29 May 2018

ASK1 deficiency attenuates neural cell death in GLAST-deficient mice, a model of normal tension glaucoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

17 August 2018

Reduced corneal thickness and enlarged anterior chamber in a novel ColVIIIa2G257D mutant mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

17 August 2018

Three experimental glaucoma models in rats: comparison of the effects of intraocular pressure elevation on retinal ganglion cell size and death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

17 August 2018

Mouse model of sustained elevation in intraocular pressure produced by episcleral vein occlusion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

17 August 2018

Predictive factors for glaucomatous visual field progression in the Advanced Glaucoma Intervention Study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

17 August 2018

Ocular hypertension in mice with a targeted type I collagen mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

17 August 2018

The Ocular Hypertension Treatment Study: baseline factors that predict the onset of primary open-angle glaucoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

17 August 2018

Collagen-related genes influence the glaucoma risk factor, central corneal thickness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3374490

1 December 2018

Morphologic changes in the lamina cribrosa correlated with neural loss in open-angle glaucoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22701298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22701298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The composition of wide-spaced collagen in normal and diseased Descemet's membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/22701298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rat model of chronic pressure-induced optic nerve damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/22701298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human sclera: thickness and surface area

1 reference

https://pubmed.ncbi.nlm.nih.gov/22701298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glaucoma drops control intraocular pressure and protect optic nerves in a rat model of glaucoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22701298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Essential iris atrophy, pigment dispersion, and glaucoma in DBA/2J mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22701298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diurnal IOP fluctuation: not an independent risk factor for glaucomatous visual field loss in high-risk ocular hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/22701298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential gene expression in mouse sclera during ocular development

1 reference

https://pubmed.ncbi.nlm.nih.gov/22701298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type VIII collagen: heterotrimeric chain association

1 reference

https://pubmed.ncbi.nlm.nih.gov/22701298

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22701298%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22701298%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

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