(Q42201524)

18 October 2017

A new activity for SAMHD1 in HIV restriction (English)

1 reference

18 October 2017

Zhiyuan Yang

1

1 reference

PubMed ID

25100520

18 October 2017

Warner C Greene

series ordinal

2

1 reference

PubMed ID

25100520

18 October 2017

language of work or name

English

0 references

publication date

1 August 2014

1 reference

18 October 2017

1 reference

18 October 2017

20

1 reference

18 October 2017

8

1 reference

18 October 2017

808-809

1 reference

https://scigraph.springernature.com/pub.10.1038/nm.3657

18 October 2017

0 references

cites work

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

1 reference

SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

21 January 2018

1 reference

SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells.

21 January 2018

1 reference

SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4(+) T-cells

21 January 2018

1 reference

The ribonuclease activity of SAMHD1 is required for HIV-1 restriction

21 January 2018

1 reference

HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase

21 January 2018

1 reference

Aicardi-Goutieres syndrome gene and HIV-1 restriction factor SAMHD1 is a dGTP-regulated deoxynucleotide triphosphohydrolase

21 January 2018

1 reference

SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates

21 January 2018

1 reference

Phosphorylation of SAMHD1 by cyclin A2/CDK1 regulates its restriction activity toward HIV-1.

21 January 2018

1 reference

The retroviral restriction ability of SAMHD1, but not its deoxynucleotide triphosphohydrolase activity, is regulated by phosphorylation

21 January 2018

1 reference

Restriction of virus infection but not catalytic dNTPase activity is regulated by phosphorylation of SAMHD1.

21 January 2018

1 reference

Nuclease activity of the human SAMHD1 protein implicated in the Aicardi-Goutieres syndrome and HIV-1 restriction.

21 January 2018

1 reference

Aicardi-Goutières syndrome: an important Mendelian mimic of congenital infection

21 January 2018

1 reference

Inhibition of CUL4A Neddylation causes a reversible block to SAMHD1-mediated restriction of HIV-1

21 January 2018

1 reference

Mechanism of allosteric activation of SAMHD1 by dGTP

21 January 2018

1 reference

Tetramerization of SAMHD1 is required for biological activity and inhibition of HIV infection

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1038/NM.3657

1 reference

18 October 2017

1 reference

PubMed ID

25100520