(Q42201669)

English

The effect of Arg306-->Ala and Arg506-->Gln substitutions in the inactivation of recombinant human factor Va by activated protein C and protein S.

scientific article published on September 1997

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

The effect of Arg306-->Ala and Arg506-->Gln substitutions in the inactivation of recombinant human factor Va by activated protein C and protein S. (English)

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

drotrecogin alfa

1 reference

based on heuristic

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author name string

J O Egan

1

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

M Kalafatis

2

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

K G Mann

3

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

publication date

1 September 1997

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

Protein Science

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

6

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

9

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

2016-2027

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

Factor VLeiden and thrombophilia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143790

26 October 2017

Molecular mechanisms of activated protein C resistance. Properties of factor V isolated from an individual with homozygosity for the Arg506 to Gln mutation in the factor V gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143790

26 October 2017

Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143790

26 October 2017

Mutation in blood coagulation factor V associated with resistance to activated protein C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143790

26 October 2017

Post-translational requirements for functional factor V and factor VIII secretion in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143790

26 October 2017

The mechanism of inactivation of human factor V and human factor Va by activated protein C

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143790

26 October 2017

Effects of protein S and factor Xa on peptide bond cleavages during inactivation of factor Va and factor VaR506Q by activated protein C

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143790

26 October 2017

Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143790

26 October 2017

Studies of the capacity of factor Xa to protect factor Va from inactivation by activated protein C

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143790

26 October 2017

Purification of human vitamin K-dependent protein S and its limited proteolysis by thrombin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143790

26 October 2017

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143790

26 October 2017

The binding of activated protein C to factors V and Va

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143790

26 October 2017

Complete cDNA and derived amino acid sequence of human factor V

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143790

26 October 2017

Cloning of a cDNA coding for human factor V, a blood coagulation factor homologous to factor VIII and ceruloplasmin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143790

26 October 2017

Cofactor proteins in the assembly and expression of blood clotting enzyme complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143790

26 October 2017

Zymogen/enzyme discrimination using peptide chloromethyl ketones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143790

26 October 2017

A general method of site-specific mutagenesis using a modification of the Thermus aquaticus polymerase chain reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143790

26 October 2017

Surface-dependent reactions of the vitamin K-dependent enzyme complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143790

26 October 2017

Improved vectors for stable expression of foreign genes in mammalian cells by use of the untranslated leader sequence from EMC virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143790

26 October 2017

The contribution of bovine Factor V and Factor Va to the activity of prothrombinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143790

26 October 2017

Human plasma protein C: isolation, characterization, and mechanism of activation by alpha-thrombin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143790

26 October 2017

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143790

26 October 2017

Platelet coagulation factor Va: the major secretory platelet phosphoprotein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143790

29 May 2018

Activated protein C resistance: molecular mechanisms based on studies using purified Gln506-factor V.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143790

29 May 2018

Simultaneous purification of bovine prothrombin and factor X. Activation of prothrombin by trypsin-activated factor X.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143790

29 May 2018

Protein polypeptide chain molecular weights by gel chromatography in guanidinium chloride

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143790

29 May 2018

pH-dependent denaturation of thrombin-activated porcine factor VIII.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143790

29 May 2018

Biochemical prototype for familial thrombosis. A study combining a functional protein C mutation and factor V Leiden.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143790

17 August 2018

Inactivation of human coagulation factor V by activated protein C

1 reference

https://pubmed.ncbi.nlm.nih.gov/9300501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolysis of factor Va by factor Xa and activated protein C

1 reference

https://pubmed.ncbi.nlm.nih.gov/9300501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The function of the human factor V carbohydrate moiety in blood coagulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9300501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetics of inactivation of membrane-bound factor Va by activated protein C. Protein S modulates factor Xa protection

1 reference

https://pubmed.ncbi.nlm.nih.gov/9300501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The reassociation of factor Va from its isolated subunits

1 reference

https://pubmed.ncbi.nlm.nih.gov/9300501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and characterization of recombinant human factor V and a mutant lacking a major portion of the connecting region

1 reference

https://pubmed.ncbi.nlm.nih.gov/9300501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human factor VIIIa subunit structure. Reconstruction of factor VIIIa from the isolated A1/A3-C1-C2 dimer and A2 subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/9300501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of factor Va and factor VIIIa by activated platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/9300501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the membrane in the inactivation of factor Va by activated protein C

1 reference

https://pubmed.ncbi.nlm.nih.gov/9300501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of membrane-dependent factor Va cleavage: a mechanistic interpretation of the pathology of protein CVermont

1 reference

https://pubmed.ncbi.nlm.nih.gov/9300501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High risk of thrombosis in patients homozygous for factor V Leiden (activated protein C resistance)

1 reference

https://pubmed.ncbi.nlm.nih.gov/9300501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Factor VNew Brunswick: Ala221-to-Val substitution results in reduced cofactor activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9300501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic events that regulate factor V activity in whole plasma from normal and activated protein C (APC)-resistant individuals during clotting: an insight into the APC-resistance assay

1 reference

https://pubmed.ncbi.nlm.nih.gov/9300501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of activated protein C/protein S-mediated inactivation of human factor VIII and factor V

1 reference

https://pubmed.ncbi.nlm.nih.gov/9300501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blood clotting in minimally altered whole blood

1 reference

https://pubmed.ncbi.nlm.nih.gov/9300501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/9300501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The subunit structure of thrombin-activated factor V. Isolation of activated factor V, separation of subunits, and reconstitution of biological activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9300501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of activated protein C by protein S. The role of phospholipid in factor Va inactivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9300501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of a membrane-bound cofactor for thrombin-catalyzed activation of protein C

1 reference

https://pubmed.ncbi.nlm.nih.gov/9300501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/PRO.5560060922

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

ResearchGate publication ID

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