(Q42202013)

https://doi.org/10.3892/ijo.2023.5525

18 October 2017

1 reference

29 December 2023

title

MicroRNA-449 suppresses proliferation of hepatoma cell lines through blockade lipid metabolic pathway related to SIRT1. (English)

1 reference

18 October 2017

1 reference

hepatocellular carcinoma

1 reference

Hongyi Zhang

1

1 reference

18 October 2017

Zhiqiang Feng

2

1 reference

18 October 2017

Rui Huang

3

1 reference

18 October 2017

Zhenglin Xia

4

1 reference

18 October 2017

Guoan Xiang

5

1 reference

18 October 2017

Jinqian Zhang

6

1 reference

18 October 2017

13 August 2014

1 reference

International Journal of Oncology

18 October 2017

1 reference

18 October 2017

45

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18 October 2017

5

1 reference

18 October 2017

2143-2152

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SIRT1 promotes tumorigenesis of hepatocellular carcinoma through PI3K/PTEN/AKT signaling.

18 October 2017

1 reference

3 January 2024

https://opencitations.net/index/api/v1/citations/10.3892/OR.2012.1788

SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Histone deacetylases activate hepatocyte growth factor signaling by repressing microRNA-449 in hepatocellular carcinoma cells

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

MicroRNAs in lipid metabolism

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Epigenetic and chromatin modifiers as targeted therapy of hematologic malignancies

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

microRNAs join the p53 network--another piece in the tumour-suppression puzzle

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Obesity-associated mechanisms of hepatocarcinogenesis

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Expression and prognostic significance of SIRT1 in ovarian epithelial tumours

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Cancer-specific functions of SIRT1 enable human epithelial cancer cell growth and survival.

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Downregulation of miR-181a upregulates sirtuin-1 (SIRT1) and improves hepatic insulin sensitivity

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Controlling SIRT1 expression by microRNAs in health and metabolic disease

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Evolving concepts in cancer therapy through targeting sphingolipid metabolism

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Stem cell division is regulated by the microRNA pathway

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

MicroRNAs as a potential magic bullet in cancer.

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

MicroRNA replacement therapy for cancer

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Activation of liver X receptors promotes lipid accumulation but does not alter insulin action in human skeletal muscle cells.

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Coactivator-dependent acetylation stabilizes members of the SREBP family of transcription factors.

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

MicroRNA-449 in cell fate determination

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Aberrant regulation of HDAC2 mediates proliferation of hepatocellular carcinoma cells by deregulating expression of G1/S cell cycle proteins

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Increased lipogenesis in cancer cells: new players, novel targets.

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

E2F1-inducible microRNA 449a/b suppresses cell proliferation and promotes apoptosis

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Hepatocellular carcinoma

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Expression of DBC1 and SIRT1 is associated with poor prognosis of gastric carcinoma

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

SREBP transcription factors: master regulators of lipid homeostasis

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP.

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Membrane rafts as potential sites of nongenomic hormonal signaling in prostate cancer

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Targeting microRNAs in cancer: rationale, strategies and challenges

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Development of hepatocellular carcinoma in a murine model of nonalcoholic steatohepatitis induced by use of a high-fat/fructose diet and sedentary lifestyle

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

MicroRNA expression profiles classify human cancers

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

In support of fatty acid synthase (FAS) as a metabolic oncogene: extracellular acidosis acts in an epigenetic fashion activating FAS gene expression in cancer cells

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Androgens, lipogenesis and prostate cancer.

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

A microRNA polycistron as a potential human oncogene

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Function of the SIRT1 protein deacetylase in cancer

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Sirtuin 1 is upregulated in a subset of hepatocellular carcinomas where it is essential for telomere maintenance and tumor cell growth.

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

The promise of microRNA replacement therapy

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

MicroRNA gene expression deregulation in human breast cancer

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Sphingolipid metabolic pathway: an overview of major roles played in human diseases

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Strong expression of a longevity-related protein, SIRT1, in Bowen's disease

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

miR-15 and miR-16 induce apoptosis by targeting BCL2

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

HDAC1 inactivation induces mitotic defect and caspase-independent autophagic cell death in liver cancer

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Microarray analyses of SREBP-1a and SREBP-1c target genes identify new regulatory pathways in muscle

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Activation of androgen receptor, lipogenesis, and oxidative stress converged by SREBP-1 is responsible for regulating growth and progression of prostate cancer cells.

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Sterol regulatory element binding protein-1c expression and action in rat muscles: insulin-like effects on the control of glycolytic and lipogenic enzymes and UCP3 gene expression

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Activation of lipogenic pathway correlates with cell proliferation and poor prognosis in hepatocellular carcinoma

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Insulin activates human sterol-regulatory-element-binding protein-1c (SREBP-1c) promoter through SRE motifs

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Fatty acid synthase: a metabolic oncogene in prostate cancer?

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Prognosis of a large cohort of patients with hepatocellular carcinoma in a single European centre

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

MicroRNAs: a new class of regulatory genes affecting metabolism

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

The role of monoacylglycerol lipase (MAGL) in the cancer progress

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

The Drosophila MicroRNA Mir-14 Suppresses Cell Death and Is Required for Normal Fat Metabolism

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR.

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

RAS is regulated by the let-7 microRNA family

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

SIRT1 is significantly elevated in mouse and human prostate cancer.

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Slowing down the Ras lane: miRNAs as tumor suppressors?

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

MicroRNA-29c functions as a tumor suppressor by direct targeting oncogenic SIRT1 in hepatocellular carcinoma

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

A microRNA expression signature of human solid tumors defines cancer gene targets

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Comprehensive analysis of the functional microRNA-mRNA regulatory network identifies miRNA signatures associated with glioma malignant progression.

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181

1 reference

9 February 2024

https://opencitations.net/index/api/v1/references/10.3892/IJO.2014.2596

Identifiers

DOI

10.3892/IJO.2014.2596

1 reference

18 October 2017

1 reference