(Q42206221)

18 October 2017

Converting cancer mutations into therapeutic opportunities (English)

1 reference

18 October 2017

Tom O'Brien

1

1 reference

PMC publication ID

3378146

18 October 2017

David Stokoe

series ordinal

2

1 reference

18 October 2017

1 September 2009

1 reference

18 October 2017

EMBO Molecular Medicine

1 reference

18 October 2017

1

1 reference

18 October 2017

6-7

1 reference

18 October 2017

297-299

1 reference

Methotrexate induces oxidative DNA damage and is selectively lethal to tumour cells with defects in the DNA mismatch repair gene MSH2

18 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378146

Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378146

Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378146

Finding and drugging the vulnerabilities of RAS-dependent cancers

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378146

Kinase requirements in human cells: III. Altered kinase requirements in VHL-/- cancer cells detected in a pilot synthetic lethal screen

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378146

Essential role for nuclear PTEN in maintaining chromosomal integrity

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378146

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378146

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378146

Lack of PTEN sequesters CHK1 and initiates genetic instability.

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378146

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

26 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3378146

Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition

26 October 2017

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20049732

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Deficiency in the Repair of DNA Damage by Homologous Recombination and Sensitivity to Poly(ADP-Ribose) Polymerase Inhibition

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FEMMM.200900044

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1002/EMMM.200900044

1 reference

18 October 2017

1 reference

PMC publication ID

3378146

18 October 2017

PubMed publication ID

20049732

1 reference

PMC publication ID

3378146