(Q42208026)

English

Studies on the mechanism of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU)-induced hepatotoxicity. II. Biochemical and morphological characterization of the injury and its prevention by phenobarbital.

scientific article published on January 1987

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scholarly article

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3105904%20AND%20SRC:MED&resulttype=core&format=json

10 October 2019

Studies on the mechanism of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU)-induced hepatotoxicity. II. Biochemical and morphological characterization of the injury and its prevention by phenobarbital (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3105904%20AND%20SRC:MED&resulttype=core&format=json

10 October 2019

1 reference

based on heuristic

inferred from title

Rokea A el-Azhary

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3105904%20AND%20SRC:MED&resulttype=core&format=json

10 October 2019

author name string

A E Ahmed

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3105904%20AND%20SRC:MED&resulttype=core&format=json

10 October 2019

M Grissom

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3105904%20AND%20SRC:MED&resulttype=core&format=json

10 October 2019

A Haque

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3105904%20AND%20SRC:MED&resulttype=core&format=json

10 October 2019

P J Boor

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3105904%20AND%20SRC:MED&resulttype=core&format=json

10 October 2019

J Costanzi

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3105904%20AND%20SRC:MED&resulttype=core&format=json

10 October 2019

publication date

1 January 1987

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3105904%20AND%20SRC:MED&resulttype=core&format=json

10 October 2019

Cancer Chemotherapy and Pharmacology

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3105904%20AND%20SRC:MED&resulttype=core&format=json

10 October 2019

19

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3105904%20AND%20SRC:MED&resulttype=core&format=json

10 October 2019

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3105904%20AND%20SRC:MED&resulttype=core&format=json

10 October 2019

103-108

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3105904%20AND%20SRC:MED&resulttype=core&format=json

10 October 2019

https://scigraph.springernature.com/pub.10.1007/bf00254560

0 references

Hydroxylation of the carcinostatic 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) by rat liver microsomes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3105904

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolonged depression of hepatic microsomal drug metabolism and hemoprotein levels following a single dose of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU)

1 reference

https://pubmed.ncbi.nlm.nih.gov/3105904

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of phenobarbital on the toxicity and tumoricidal activity of CCNU in a murine brain tumor model.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3105904

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of phenobarbital pretreatment on the antitumor activity of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU), 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) and 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidyl-1-nitrosourea (PCNU), and on the pl

1 reference

https://pubmed.ncbi.nlm.nih.gov/3105904

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE

1 reference

https://pubmed.ncbi.nlm.nih.gov/3105904

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of phenobarbital-induced hypercholeresis in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3105904

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heme metabolism in liver and spleen of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU)-treated rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/3105904

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum enzymes in hepatotoxicity induced by chloroethylcyclohexyl nitrosourea and arabinofuranosyl-6-mercaptopurine

1 reference

https://pubmed.ncbi.nlm.nih.gov/3105904

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The hepatotoxicity of 1,3-bis (2-chloroethyl)-1-nitrosurea (BCNU) in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/3105904

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the properties of metabolites of CCNU

1 reference

https://pubmed.ncbi.nlm.nih.gov/3105904

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenobarbital-induced alterations of bile acid metabolism in cases of intrahepatic cholestasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/3105904

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective bromosulfophthalein clearance in patients with constitutional hepatic dysfunction (Gilbert's syndrome)

1 reference

https://pubmed.ncbi.nlm.nih.gov/3105904

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of phenobarbital on hyperbilirubinemia, bile acid metabolism, and microsomal enzyme activity in chronic intrahepatic cholestasis of childhood

1 reference

https://pubmed.ncbi.nlm.nih.gov/3105904

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein measurement with the Folin phenol reagent

1 reference

https://pubmed.ncbi.nlm.nih.gov/3105904

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sex-dependent differences in drug metabolism in the rat. I. Temporal changes in microsomal drug-metabolizing system of the liver during sexual maturation

1 reference

https://pubmed.ncbi.nlm.nih.gov/3105904

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitrosoureas: 1,3-bis(2-chloroethyl)-1-nitrosourea (NSC-409962; BCNU) and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (NSC-79037; CCNU)--clinical brochure

1 reference

https://pubmed.ncbi.nlm.nih.gov/3105904

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatotoxicity of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) in dogs: The use of serial percutaneous liver biopsies

1 reference

https://pubmed.ncbi.nlm.nih.gov/3105904

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in the toxicity and antitumor activity of methyl-CCNU in mice following pretreatment with either phenobarbital or SKF 525A

1 reference

https://pubmed.ncbi.nlm.nih.gov/3105904

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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