(Q42215725)

18 October 2017

title

Mechanistic studies for tri-targeted inhibition of enzymes involved in cholesterol biosynthesis by green tea polyphenols (English)

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18 October 2017

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Hu Ge

1

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18 October 2017

Jinggong Liu

2

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18 October 2017

Wenxia Zhao

3

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18 October 2017

Yu Wang

4

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18 October 2017

Qingqing He

5

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18 October 2017

Ruibo Wu

6

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18 October 2017

Ding Li

7

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18 October 2017

Jun Xu

8

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18 October 2017

publication date

1 July 2014

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Organic and Biomolecular Chemistry

18 October 2017

published in

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18 October 2017

volume

12

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18 October 2017

issue

27

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18 October 2017

page(s)

4941-4951

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Tea polyphenols for health promotion

18 October 2017

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Green tea as inhibitor of the intestinal absorption of lipids: potential mechanism for its lipid-lowering effect

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Green and black tea extracts inhibit HMG-CoA reductase and activate AMP kinase to decrease cholesterol synthesis in hepatoma cells

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The structure of a binary complex between a mammalian mevalonate kinase and ATP: insights into the reaction mechanism and human inherited disease

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Investigation of invariant serine/threonine residues in mevalonate kinase. Tests of the functional significance of a proposed substrate binding motif and a site implicated in human inherited disease

21 January 2018

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Organization of the mevalonate kinase (MVK) gene and identification of novel mutations causing mevalonic aciduria and hyperimmunoglobulinaemia D and periodic fever syndrome

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Purification of rat liver mevalonate pyrophosphate decarboxylase

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Identification of active site residues in mevalonate diphosphate decarboxylase: implications for a family of phosphotransferases

21 January 2018

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Probucol Decreases Mevalonate Pyrophosphate Decarboxylase in the Rat Liver

21 January 2018

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Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs.

21 January 2018

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The regulation of activity of main mevalonic acid pathway enzymes: farnesyl diphosphate synthase, 3-hydroxy-3-methylglutaryl-CoA reductase, and squalene synthase in yeast Saccharomyces cerevisiae.

21 January 2018

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Comparative evaluation of eight docking tools for docking and virtual screening accuracy

21 January 2018

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Evaluation of the performance of 3D virtual screening protocols: RMSD comparisons, enrichment assessments, and decoy selection--what can we learn from earlier mistakes?

21 January 2018

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A new protocol for predicting novel GSK-3β ATP competitive inhibitors

21 January 2018

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Glossary of terms used in medicinal chemistry (IUPAC Recommendations 1998)

21 January 2018

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Selecting diversified compounds to build a tangible library for biological and biochemical assays.

21 January 2018

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Discovery of potent inhibitor for farnesyl pyrophosphate synthase in the mevalonate pathway

21 January 2018

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Cloning, expression, and purification of His-tagged rat mevalonate kinase

21 January 2018

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Thermal, chemical, and enzymatic stability of the cyclotide kalata B1: the importance of the cyclic cystine knot.

21 January 2018

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Merck molecular force field. I. Basis, form, scope, parameterization, and performance of MMFF94

21 January 2018

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Automatic atom type and bond type perception in molecular mechanical calculations

21 January 2018

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21 January 2018

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Routine Microsecond Molecular Dynamics Simulations with AMBER on GPUs. 1. Generalized Born

21 January 2018

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Molecular dynamics-based virtual screening: accelerating the drug discovery process by high-performance computing

21 January 2018

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Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanes

21 January 2018

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MMPBSA.py: An Efficient Program for End-State Free Energy Calculations

21 January 2018

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Assessing the performance of the MM/PBSA and MM/GBSA methods. 1. The accuracy of binding free energy calculations based on molecular dynamics simulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC4OB00589A

21 January 2018

Identifiers

DOI

10.1039/C4OB00589A

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18 October 2017

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