(Q42217000)

English

Importance of the glutamate residue of KDEL in increasing the cytotoxicity of Pseudomonas exotoxin derivatives and for increased binding to the KDEL receptor

scientific article published on April 1995

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

Importance of the glutamate residue of KDEL in increasing the cytotoxicity of Pseudomonas exotoxin derivatives and for increased binding to the KDEL receptor (English)

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

0 references

author name string

Kreitman RJ

1

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

Pastan I

2

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

language of work or name

0 references

publication date

1 April 1995

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

number of pages

9

1 reference

based on heuristic

inferred from page(s)

Biochemical Journal

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

307 ( Pt 1)

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

29-37

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

pH-dependent binding of KDEL to its receptor in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

26 October 2017

The N-terminal region of the 37-kDa translocated fragment of Pseudomonas exotoxin A aborts translocation by promoting its own export after microsomal membrane insertion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

26 October 2017

A C-terminal signal prevents secretion of luminal ER proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

26 October 2017

Evidence that luminal ER proteins are sorted from secreted proteins in a post-ER compartment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

26 October 2017

Structure of exotoxin A of Pseudomonas aeruginosa at 3.0-Angstrom resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

26 October 2017

Control of protein exit from the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

26 October 2017

Nucleotide sequence of cDNA coding for rat liver pI 6.1 esterase (ES-10), a carboxylesterase located in the lumen of the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

26 October 2017

Variants of the carboxyl-terminal KDEL sequence direct intracellular retention.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

26 October 2017

ERp72, an abundant luminal endoplasmic reticulum protein, contains three copies of the active site sequences of protein disulfide isomerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

26 October 2017

A recombinant single-chain immunotoxin composed of anti-Tac variable regions and a truncated diphtheria toxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

26 October 2017

Recycling of proteins from the Golgi compartment to the ER in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

26 October 2017

The ERD2 gene determines the specificity of the luminal ER protein retention system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

26 October 2017

ERD2, a yeast gene required for the receptor-mediated retrieval of luminal ER proteins from the secretory pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

26 October 2017

A human homologue of the yeast HDEL receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

26 October 2017

Processing of Pseudomonas exotoxin by a cellular protease results in the generation of a 37,000-Da toxin fragment that is translocated to the cytosol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

26 October 2017

Pseudomonas exotoxin contains a specific sequence at the carboxyl terminus that is required for cytotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

26 October 2017

The retention signal for soluble proteins of the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

26 October 2017

Analysis of the retention signals of two resident luminal endoplasmic reticulum proteins by in vitro mutagenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

26 October 2017

Increased cytotoxic activity of Pseudomonas exotoxin and two chimeric toxins ending in KDEL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

26 October 2017

The carboxylesterase family exhibits C-terminal sequence diversity reflecting the presence or absence of endoplasmic-reticulum-retention sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

26 October 2017

Cell-mediated cleavage of Pseudomonas exotoxin between Arg279 and Gly280 generates the enzymatically active fragment which translocates to the cytosol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

26 October 2017

Analysis of the BiP gene and identification of an ER retention signal in Schizosaccharomyces pombe

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

26 October 2017

Sequence of a second human KDEL receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

26 October 2017

Purification and characterization of a rat liver Golgi alpha-mannosidase capable of processing asparagine-linked oligosaccharides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

26 October 2017

A developmentally regulated gene of trypanosomes encodes a homologue of rat protein-disulfide isomerase and phosphoinositol-phospholipase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

29 May 2018

Recombinant toxins containing the variable domains of the anti-Tac monoclonal antibody to the interleukin-2 receptor kill malignant cells from patients with chronic lymphocytic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

29 May 2018

Single-chain immunotoxin fusions between anti-Tac and Pseudomonas exotoxin: relative importance of the two toxin disulfide bonds.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

29 May 2018

Functional domains of Pseudomonas exotoxin identified by deletion analysis of the gene expressed in E. coli.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

29 May 2018

Functional analysis of domains II, Ib, and III of Pseudomonas exotoxin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

29 May 2018

Affinity purification and characterization of anti-Tac(Fv)-C3-PE38KDEL: A highly potent cytotoxic agent specific to cells bearing IL-2 receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1136741

17 August 2018

Recombinant immunotoxins containing anti-Tac(Fv) and derivatives of Pseudomonas exotoxin produce complete regression in mice of an interleukin-2 receptor-expressing human carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/7717988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-4 receptors expressed on tumor cells may serve as a target for anticancer therapy using chimeric Pseudomonas exotoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/7717988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changing the specificity of the sorting receptor for luminal endoplasmic reticulum proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/7717988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different sorting of Lys-Asp-Glu-Leu proteins in rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/7717988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rational design of a chimeric toxin: an intramolecular location for the insertion of transforming growth factor .alpha. within Pseudomonas exotoxin as a targeting ligand

1 reference

https://pubmed.ncbi.nlm.nih.gov/7717988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein binds and internalizes Pseudomonas exotoxin A

1 reference

https://pubmed.ncbi.nlm.nih.gov/7717988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monovalent immunotoxin containing truncated form of Pseudomonas exotoxin as potent antitumor agent

1 reference

https://pubmed.ncbi.nlm.nih.gov/7717988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A method for increasing the yield of properly folded recombinant fusion proteins: single-chain immunotoxins from renaturation of bacterial inclusion bodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/7717988

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ3070029

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 October 2017

ResearchGate publication ID

0 references

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