(Q42220644)

English

Altered pharmacokinetics in the mechanism of chemosensitization: effects of nitroimidazoles and other chemical modifiers on the pharmacokinetics, antitumour activity and acute toxicity of selected nitrogen mustards

scientific article published on January 1986

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

18 October 2017

Altered pharmacokinetics in the mechanism of chemosensitization: effects of nitroimidazoles and other chemical modifiers on the pharmacokinetics, antitumour activity and acute toxicity of selected nitrogen mustards (English)

1 reference

Europe PubMed Central

PubMed publication ID

18 October 2017

pharmacokinetics

1 reference

based on heuristic

inferred from title

author name string

F Y Lee

1

1 reference

Europe PubMed Central

PubMed publication ID

18 October 2017

P Workman

2

1 reference

Europe PubMed Central

PubMed publication ID

18 October 2017

publication date

1 January 1986

1 reference

Europe PubMed Central

PubMed publication ID

18 October 2017

Cancer Chemotherapy and Pharmacology

1 reference

Europe PubMed Central

PubMed publication ID

18 October 2017

17

1 reference

Europe PubMed Central

PubMed publication ID

18 October 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

18 October 2017

30-37

1 reference

Europe PubMed Central

PubMed publication ID

18 October 2017

Modification of chemotherapy by nitroimidazoles

1 reference

https://pubmed.ncbi.nlm.nih.gov/3698174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Factors influencing the chemosensitization of melphalan by misonidazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/3698174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Misonidazole and CCNU: further evidence for a pharmacokinetic mechanism of chemosensitization and therapeutic gain

1 reference

https://pubmed.ncbi.nlm.nih.gov/3698174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mechanisms of cytotoxicity and chemosensitization by misonidazole and other nitroimidazoles.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3698174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I trial of intravenous L-phenylalanine mustard plus the sensitizer misonidazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/3698174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic basis for the comparative antitumour activity and toxicity of chlorambucil, phenylacetic acid mustard and beta, beta-difluorochlorambucil (CB 7103) in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/3698174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitroimidazoles as modifiers of nitrosourea pharmacokinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/3698174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The metabolism of chlorambucil

1 reference

https://pubmed.ncbi.nlm.nih.gov/3698174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Misonidazole enhancement of the action of BCNU and melphalan against human melanoma xenografts

1 reference

https://pubmed.ncbi.nlm.nih.gov/3698174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro degradation of L-phenylalanine mustard (L-PAM)

1 reference

https://pubmed.ncbi.nlm.nih.gov/3698174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of radiosensitizer pretreatment on the response of the RIF-1 mouse sarcoma to cytotoxic drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/3698174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced cell killing in lewis lung carcinoma and a human pancreatic-carcinoma xenograft by the combination of cytotoxic drugs and misonidazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/3698174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement by electron-affinic agents of the therapeutic effects of cytotoxic agents against the KHT tumor: structure-activity relationships

1 reference

https://pubmed.ncbi.nlm.nih.gov/3698174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of the action of alkylating agents by single high, or chronic low doses of misonidazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/3698174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potentiation of melphalan activity against a murine tumour by nitroimidazole compounds

1 reference

https://pubmed.ncbi.nlm.nih.gov/3698174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phase I study of the combination of benznidazole and CCNU in man.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3698174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of radiosensitizers on the pharmacokinetics of melphalan and cyclophosphamide in the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/3698174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo interaction of anti-cancer drugs with misonidazole or metronidazole: cyclophosphamide and BCNU.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3698174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potentiation of melphalan activity in the KHT sarcoma by the radiosensitizer RSU 1069

1 reference

https://pubmed.ncbi.nlm.nih.gov/3698174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An investigation of the possibility of chemosensitization by clinically achievable concentrations of misonidazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/3698174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of chemotherapy agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/3698174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modification of CCNU pharmacokinetics by misonidazole--a major mechanism of chemosensitization in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/3698174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of clinical levels of misonidazole on the response of tumour and normal tissues in the mouse to alkylating agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/3698174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug metabolism and chemosensitization. Nitroimidazoles as inhibitors of drug metabolism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/3698174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of melphalan-induced tumour cell killing by misonidazole: an interaction of competing mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/3698174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF00299862

1 reference

Europe PubMed Central

PubMed publication ID

18 October 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 October 2017

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