(Q42261569)

English

In vivo evidence for free radical involvement in the degeneration of rat brain 5-HT following administration of MDMA ('ecstasy') and p-chloroamphetamine but not the degeneration following fenfluramine

scientific article published on July 1997

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

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In vivo evidence for free radical involvement in the degeneration of rat brain 5-HT following administration of MDMA ('ecstasy') and p-chloroamphetamine but not the degeneration following fenfluramine (English)

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

author name string

Colado MI

1

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

O'Shea E

2

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Granados R

3

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Murray TK

4

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Green AR

5

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

language of work or name

0 references

publication date

1 July 1997

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

British Journal of Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

121

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

5

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

889-900

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

Attenuation by chlormethiazole administration of the rise in extracellular amino acids following focal ischaemia in the cerebral cortex of the rat.

1 reference

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21 January 2018

Small differences in intraischemic brain temperature critically determine the extent of ischemic neuronal injury

1 reference

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21 January 2018

A study of the mechanism of MDMA ('ecstasy')-induced neurotoxicity of 5-HT neurones using chlormethiazole, dizocilpine and other protective compounds

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

21 January 2018

5-HT loss in rat brain following 3,4-methylenedioxymethamphetamine (MDMA), p-chloroamphetamine and fenfluramine administration and effects of chlormethiazole and dizocilpine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

21 January 2018

The hyperthermic and neurotoxic effects of ‘Ecstasy’ (MDMA) and 3,4 methylenedioxyamphetamine (MDA) in the Dark Agouti (DA) rat, a model of the CYP2D6 poor metabolizer phenotype

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

21 January 2018

Ecstasy and neurodegeneration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

21 January 2018

Ecstasy and neurodegeneration. No evidence of neurotoxicity exists

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

21 January 2018

CuZn-superoxide dismutase (CuZnSOD) transgenic mice show resistance to the lethal effects of methylenedioxyamphetamine (MDA) and of methylenedioxymethamphetamine (MDMA).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

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Protection against oxidative damage to CNS by α-phenyl-tert-butyl nitrone (PBN) and other spin-trapping agents: A novel series of nonlipid free radical scavengers

1 reference

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7 January 2021

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Distribution of spin-trapping compounds in rat blood and brain: in vivo microdialysis determination.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

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Intracranial microdialysis of salicylic acid to detect hydroxyl radical generation through dopamine autooxidation in the caudate nucleus: effects of MPP+

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

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The spin trap reagent alpha-phenyl-N-tert-butyl nitrone prevents 'ecstasy'-induced neurodegeneration of 5-hydroxytryptamine neurones

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

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A study of the neurotoxic effect of MDMA ('ecstasy') on 5-HT neurones in the brains of mothers and neonates following administration of the drug during pregnancy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

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Reorganization of ascending 5-HT axon projections in animals previously exposed to the recreational drug (+/-)3,4-methylenedioxymethamphetamine (MDMA, "ecstasy").

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

Sensitive assay of hydroxyl free radical formation utilizing high pressure liquid chromatography with electrochemical detection of phenol and salicylate hydroxylation products.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

Reversible and irreversible phases of serotonin depletion by 4-chloroamphetamine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

Estimating hydroxyl radical content in rat brain using systemic and intraventricular salicylate: impact of methamphetamine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

Detection of free radical activity during transient global ischemia and recirculation: effects of intraischemic brain temperature modulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

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Review of the pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA or "Ecstasy").

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

Hydroxylation of salicylate as an assay for hydroxyl radicals: a cautionary note

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

Reserpine does not prevent 3,4-methylenedioxymethamphetamine-induced neurotoxicity in the rat

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

Chlormethiazole, dizocilpine and haloperidol prevent the degeneration of serotonergic nerve terminals induced by administration of MDMA ('Ecstasy') to rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

Brain temperature alters hydroxyl radical production during cerebral ischemia/reperfusion in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

Ion trap tandem mass spectrometric evidence for the metabolism of 3,4-(methylenedioxy)methamphetamine to the potent neurotoxins 2,4,5-trihydroxymethamphetamine and 2,4,5-trihydroxyamphetamine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

Dopamine-derived 1-methyl-6,7-dihydroxyisoquinolines as hydroxyl radical promoters and scavengers in the rat brain: in vivo and in vitro studies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

Neurotoxicity of MDMA and related compounds: anatomic studies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

The spin trap reagent PBN attenuates degeneration of 5-HT neurones in rat brain induced by p-chloroamphetamine but not fenfluramine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

The action of fenfluramine andp-chloramphetamine on serotonergic mechanisms: A comparative study in rat brain nuclei.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

Intracranial microdialysis of salicylic acid to detect hydroxyl radical generation by monoamine oxidase inhibitor in the rat

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain: immunocytochemical evidence for neurotoxicity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

Lack of serotonin neurotoxicity after intraraphe microinjection of (+)-3,4-methylenedioxymethamphetamine (MDMA)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

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Determination of hydroxylated aromatic compounds produced via superoxide-dependent formation of hydroxyl radicals by liquid chromatography/electrochemistry

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

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5-Hydroxyindoleacetic acid in cerebrospinal fluid reflects serotonergic damage induced by 3,4-methylenedioxymethamphetamine in CNS of non-human primates

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

Long-term effects of p-chloroamphetamine on tryptophan hydroxylase activity and on the levels of 5-hydroxytryptamine and 5-hydroxyindole acetic acid in brain.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

Neurotoxicity of MDMA: neurochemical effects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

Methylenedioxymethamphetamine: a potentially neurotoxic amphetamine analogue

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

alpha-Phenyl-tert-butyl-nitrone (PBN) attenuates hydroxyl radical production during ischemia-reperfusion injury of rat brain: an EPR study.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

Alterations in hippocampal function following repeated exposure to the amphetamine derivative methylenedioxymethamphetamine ("Ecstasy").

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

3,4-Methylenedioxymethamphetamine (MDMA, "Ecstasy"): pharmacology and toxicology in animals and humans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of cysteine on the persistent depletion of brain monoamines by amphetamine, p-chloroamphetamine and MPTP

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

The effects of 3,4-methylenedioxymethamphetamine (MDMA) and 3,4-methylenedioxyamphetamine (MDA) on monoaminergic systems in the rat brain.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

The demethylenation of methylenedioxymethamphetamine ("ecstasy") by debrisoquine hydroxylase (CYP2D6)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

Distinct morphologic classes of serotonergic axons in primates exhibit differential vulnerability to the psychotropic drug 3,4-methylenedioxymethamphetamine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

Apparent antioxidant effect of l-deprenyl on hydroxyl radical formation and nigral injury elicited by MPP+ in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

Delayed treatment with the spin trap alpha-phenyl-N-tert-butyl nitrone (PBN) reduces infarct size following transient middle cerebral artery occlusion in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

Detection of free radicals during brain ischemia and reperfusion by spin trapping and microdialysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0701213

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.BJP.0701213

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 October 2017

ResearchGate publication ID

0 references

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