(Q42284296)

English

Polymorphisms in the cytochrome P450 CYP1A2 gene (CYP1A2) in colorectal cancer patients and controls: allele frequencies, linkage disequilibrium and influence on caffeine metabolism.

scientific article published on January 2003

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12534642%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

Polymorphisms in the cytochrome P450 CYP1A2 gene (CYP1A2) in colorectal cancer patients and controls: allele frequencies, linkage disequilibrium and influence on caffeine metabolism (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12534642%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

0 references

colorectal cancer

1 reference

based on heuristic

inferred from title

colorectal carcinoma

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

linkage disequilibrium

1 reference

based on heuristic

inferred from title

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12534642%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

5

1 reference

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16 December 2019

8

1 reference

Europe PubMed Central

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16 December 2019

9

1 reference

Europe PubMed Central

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16 December 2019

author name string

Christoph Sachse

1

1 reference

Europe PubMed Central

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16 December 2019

Upinder Bhambra

2

1 reference

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16 December 2019

Tracy J Lightfoot

4

1 reference

Europe PubMed Central

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16 December 2019

Jenna Scollay

6

1 reference

Europe PubMed Central

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16 December 2019

R Colin Garner

7

1 reference

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16 December 2019

Nigel J Gooderham

10

1 reference

Europe PubMed Central

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16 December 2019

Colorectal Cancer Study Group

11

1 reference

Europe PubMed Central

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16 December 2019

language of work or name

0 references

publication date

1 January 2003

1 reference

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16 December 2019

British Journal of Clinical Pharmacology

1 reference

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16 December 2019

55

1 reference

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16 December 2019

68-76

1 reference

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16 December 2019

1

1 reference

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16 December 2019

Brassica vegetables increase and apiaceous vegetables decrease cytochrome P450 1A2 activity in humans: changes in caffeine metabolite ratios in response to controlled vegetable diets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884179

26 October 2017

Functional significance of a C-->A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884179

26 October 2017

Detection of a novel cytochrome P-450 1A2 polymorphism (F21L) in Chinese

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884179

26 October 2017

Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884179

26 October 2017

Heterocyclic amines: evaluation of their role in diet associated human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884179

26 October 2017

The human CYP1A2 gene and induction by 3-methylcholanthrene. A region of DNA that supports AH-receptor binding and promoter-specific induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884179

26 October 2017

Caffeine phenotyping of cytochrome P4501A2, N-acetyltransferase, and xanthine oxidase in patients with familial adenomatous polyposis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884179

26 October 2017

Genotyping for polymorphisms in xenobiotic metabolism as a predictor of disease susceptibility.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884179

26 October 2017

Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884179

26 October 2017

Use of caffeine metabolite ratios to explore CYP1A2 and xanthine oxidase activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884179

26 October 2017

Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884179

29 May 2018

Five novel natural allelic variants-951A>C, 1042G>A (D348N), 1156A>T (I386F), 1217G>A (C406Y) and 1291C>T (C431Y)-of the human CYP1A2 gene in a French Caucasian population.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884179

17 August 2018

Identification of novel polymorphisms in the 5' flanking region of CYP1A2, characterization of interethnic variability, and investigation of their functional significance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884179

17 August 2018

Model-free analysis and permutation tests for allelic associations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884179

17 August 2018

Detection of three genetic polymorphisms in the 5'-flanking region and intron 1 of human CYP1A2 in the Japanese population.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884179

17 August 2018

Nomenclature for human CYP2D6 alleles.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884179

17 August 2018

Rapid metabolic phenotypes for acetyltransferase and cytochrome P4501A2 and putative exposure to food-borne heterocyclic amines increase the risk for colorectal cancer or polyps.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884179

17 August 2018

Polymorphisms of CYP1A1 and GSTM1 influence the in vivo function of CYP1A2

1 reference

https://pubmed.ncbi.nlm.nih.gov/12534642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic polymorphism in the 5'-flanking region of human CYP1A2 gene: effect on the CYP1A2 inducibility in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/12534642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detailed modelling of caffeine metabolism and examination of the CYP1A2 gene: lack of a polymorphism in CYP1A2 in Caucasians

1 reference

https://pubmed.ncbi.nlm.nih.gov/12534642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A urinary metabolite ratio that reflects systemic caffeine clearance

1 reference

https://pubmed.ncbi.nlm.nih.gov/12534642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caffeine as a metabolic probe: exploration of the enzyme-inducing effect of cigarette smoking

1 reference

https://pubmed.ncbi.nlm.nih.gov/12534642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CYP1A2-catalyzed conversion of dietary heterocyclic amines to their proximate carcinogens is their major route of metabolism in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/12534642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenotyping of CYP1A2 in Japanese population by analysis of caffeine urinary metabolites: absence of mutation prescribing the phenotype in the CYP1A2 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/12534642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1046/J.1365-2125.2003.01733.X

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12534642%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12534642%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12534642%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

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