(Q42288166)

19 October 2017

title

Model peptides to study the effects of P2 and P3 substitutions in statine-containing HIV proteinase inhibitors (English)

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19 October 2017

Hui KY

1

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19 October 2017

Hermann RB

2

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19 October 2017

Manetta JV

3

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19 October 2017

Gygi T

4

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19 October 2017

Angleton EL

5

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19 October 2017

language of work or name

English

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publication date

1 August 1993

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19 October 2017

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19 October 2017

volume

327

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19 October 2017

issue

3

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19 October 2017

page(s)

355-360

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Processing of the precursor of NF-kappa B by the HIV-1 protease during acute infection

19 October 2017

cites work

1 reference

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HIV-1 proteinase is required for synthesis of pro-viral DNA.

21 January 2018

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Non-viral cellular substrates for human immunodeficiency virus type 1 protease

21 January 2018

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HIV protease: a novel chemotherapeutic target for AIDS.

21 January 2018

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Statine based tripeptides as potent inhibitors of HIV-1 replication

21 January 2018

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Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1

21 January 2018

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Conserved folding in retroviral proteases: crystal structure of a synthetic HIV-1 protease

21 January 2018

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X-ray analysis of HIV-1 proteinase at 2.7 A resolution confirms structural homology among retroviral enzymes

21 January 2018

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Structure of complex of synthetic HIV-1 protease with a substrate-based inhibitor at 2.3 A resolution

21 January 2018

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Mutating P2 and P1 residues at cleavage junctions in the HIV-1 pol polyprotein. Effects on hydrolysis by HIV-1 proteinase.

21 January 2018

1 reference

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Sub-site preferences of the aspartic proteinase from the human immunodeficiency virus, HIV-1.

21 January 2018

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Different requirements for productive interaction between the active site of HIV-1 proteinase and substrates containing -hydrophobic*hydrophobic- or -aromatic*pro- cleavage sites

21 January 2018

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https://api.crossref.org/works/10.1016%2F0014-5793%2893%2981020-Z

Kinetic and modeling studies of S3-S3' subsites of HIV proteinases

21 January 2018

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Reduced-bond tight-binding inhibitors of HIV-1 protease. Fine tuning of the enzyme subsite specificity

21 January 2018

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Substitutions at the P2' site of gag p17-p24 affect cleavage efficiency by HIV-1 protease

21 January 2018

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Rational design of peptide-based HIV proteinase inhibitors

21 January 2018

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Hydroxyethylamine analogues of the p17/p24 substrate cleavage site are tight-binding inhibitors of HIV protease

21 January 2018

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Inhibition of human immunodeficiency virus 1 protease in vitro: rational design of substrate analogue inhibitors

21 January 2018

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Hydroxyethylene isostere inhibitors of human immunodeficiency virus-1 protease: structure-activity analysis using enzyme kinetics, X-ray crystallography, and infected T-cell assays

21 January 2018

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HIV-1 protease inhibitors based on hydroxyethylene dipeptide isosteres: an investigation into the role of the P1' side chain on structure-activity

21 January 2018

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Design, activity, and 2.8 A crystal structure of a C2 symmetric inhibitor complexed to HIV-1 protease

21 January 2018

1 reference

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X-ray crystallographic structure of a complex between a synthetic protease of human immunodeficiency virus 1 and a substrate-based hydroxyethylamine inhibitor

21 January 2018

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Effective blocking of HIV-1 proteinase activity by characteristic inhibitors of aspartic proteinases

21 January 2018

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Inhibitors of the protease from human immunodeficiency virus: design and modeling of a compound containing a dihydroxyethylene isostere insert with high binding affinity and effective antiviral activity

21 January 2018

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Benzocycloalkyl amines as novel C-termini for HIV protease inhibitors

21 January 2018

1 reference

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Design and synthesis of HIV protease inhibitors. Variations of the carboxy terminus of the HIV protease inhibitor L-682,679

21 January 2018

1 reference

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Fibronectin is a non-viral substrate for the HIV proteinase

21 January 2018

1 reference

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Design of potent substrate-analogue inhibitors of canine renin

21 January 2018

1 reference

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Analysis of subsite preferences of HIV-1 proteinase using MA/CA junction peptides substituted at the P3-P1' positions

21 January 2018

1 reference

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10.1016/0014-5793(93)81020-Z

21 January 2018

Identifiers

DOI

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19 October 2017

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