(Q42382771)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27267850%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

title

A Novel HSP90 Inhibitor-Drug Conjugate to SN38 Is Highly Effective in Small Cell Lung Cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27267850%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27267850%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Yanis Boumber

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27267850%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

author name string

Anna V Gaponova

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27267850%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Anna S Nikonova

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27267850%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Alexander Deneka

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27267850%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Meghan C Kopp

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27267850%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Alexander E Kudinov

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27267850%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Natalia Skobeleva

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27267850%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Vladimir Khazak

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27267850%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Luisa S Ogawa

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27267850%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Kathy Q Cai

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27267850%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Kelly E Duncan

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27267850%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

James S Duncan

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27267850%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

David A Proia

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27267850%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Erica A Golemis

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27267850%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

language of work or name

English

0 references

publication date

7 June 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27267850%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

published in

Clinical Cancer Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27267850%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

volume

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27267850%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

issue

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27267850%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

page(s)

5120-5129

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27267850%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

12 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5065742/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

HSP90 Inhibitor-SN-38 Conjugate Strategy for Targeted Delivery of Topoisomerase I Inhibitor to Tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065742

Comprehensive genomic profiles of small cell lung cancer

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065742

Small cell lung cancer: where do we go from here?

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065742

Treatment of small cell lung cancer in academic and community settings: factors associated with receiving standard therapy and survival

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065742

Asymmetric Hsp90 N domain SUMOylation recruits Aha1 and ATP-competitive inhibitors

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065742

HSP-90 inhibitor ganetespib is synergistic with doxorubicin in small cell lung cancer.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065742

Application of multiplexed kinase inhibitor beads to study kinome adaptations in drug-resistant leukemia

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065742

28 May 2018

Cancer statistics, 2013

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065742

Topoisomerase degradation, DSB repair, p53 and IAPs in cancer cell resistance to camptothecin-like topoisomerase I inhibitors

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065742

Genomic landscape of non-small cell lung cancer in smokers and never-smokers

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065742

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065742

Tumor-intrinsic and tumor-extrinsic factors impacting hsp90- targeted therapy

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065742

Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065742

The heat shock proteins as targets for radiosensitization and chemosensitization in cancer

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065742

The ATM substrate KAP1 controls DNA repair in heterochromatin: regulation by HP1 proteins and serine 473/824 phosphorylation

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065742

Drug targeting to tumors: principles, pitfalls and (pre-) clinical progress.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065742

Equivalent effect of DNA damage-induced apoptotic cell death or long-term cell cycle arrest on colon carcinoma cell proliferation and tumour growth

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065742

Polo-like kinase 1 phosphorylates cyclin B1 and targets it to the nucleus during prophase

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065742

Induction of p53-dependent and p53-independent cellular responses by topoisomerase 1 inhibitors

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065742

Preclinical evaluation of CPT-11 and its active metabolite SN-38.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065742

Establishment of continuous, clonable cultures of small-cell carcinoma of lung which have amine precursor uptake and decarboxylation cell properties

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065742

Cytometric assessment of histone H2AX phosphorylation: a reporter of DNA damage

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065742

Twenty years of phase III trials for patients with extensive-stage small-cell lung cancer: perceptible progress

16 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27267850

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/1078-0432.CCR-15-3068

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27267850%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27267850%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference