(Q42428056)

English

Insight into the function of DIO2, a susceptibility gene in human osteoarthritis, as an inducer of cartilage damage in a rat model: is there a role for chondrocyte hypertrophy?

scientific article published on 6 March 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

0 references

Insight into the function of DIO2, a susceptibility gene in human osteoarthritis, as an inducer of cartilage damage in a rat model: is there a role for chondrocyte hypertrophy? (English)

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

0 references

1 reference

based on heuristic

inferred from title

author name string

M B Goldring

1

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

publication date

6 March 2013

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

Osteoarthritis and Cartilage

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

21

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

5

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

643-645

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937864

28 May 2018

Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937864

28 May 2018

DIO2 modifies inflammatory responses in chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937864

28 May 2018

Chondrocyte hypertrophy and osteoarthritis: role in initiation and progression of cartilage degeneration?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937864

28 May 2018

A variant in MCF2L is associated with osteoarthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937864

28 May 2018

Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937864

28 May 2018

Thyroid hormone-mediated growth and differentiation of growth plate chondrocytes involves IGF-1 modulation of beta-catenin signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937864

28 May 2018

The clinical relevance of genetic susceptibility to osteoarthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937864

28 May 2018

A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937864

28 May 2018

Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937864

28 May 2018

New insights into osteoarthritis: early developmental features of an ageing-related disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937864

28 May 2018

Differential expression of GADD45beta in normal and osteoarthritic cartilage: potential role in homeostasis of articular chondrocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937864

28 May 2018

Integration of signaling pathways regulating chondrocyte differentiation during endochondral bone formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937864

28 May 2018

Thyroid hormone interacts with the Wnt/beta-catenin signaling pathway in the terminal differentiation of growth plate chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937864

28 May 2018

Characterization of the nuclear factor-kappa B responsiveness of the human dio2 gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937864

28 May 2018

The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937864

28 May 2018

Thyroxine is the serum factor that regulates morphogenesis of columnar cartilage from isolated chondrocytes in chemically defined medium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937864

28 May 2018

Deiodinase 2 upregulation demonstrated in osteoarthritis patients cartilage causes cartilage destruction in tissue-specific transgenic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937864

16 August 2018

Genetic variation in the SMAD3 gene is associated with hip and knee osteoarthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937864

16 August 2018

Genome-wide expression profiling reveals new candidate genes associated with osteoarthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937864

16 August 2018

Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937864

16 August 2018

In serum-free culture thyroid hormones can induce full expression of chondrocyte hypertrophy leading to matrix calcification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3937864

16 August 2018

Meta-analyses of genes modulating intracellular T3 bio-availability reveal a possible role for the DIO3 gene in osteoarthritis susceptibility

1 reference

https://pubmed.ncbi.nlm.nih.gov/23473975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Osteoarthritis susceptibility genes influence the association between hip morphology and osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23473975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased type II deiodinase protein in OA-affected cartilage and allelic imbalance of OA risk polymorphism rs225014 at DIO2 in human OA joint tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/23473975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Large-scale gene expression profiling reveals major pathogenetic pathways of cartilage degeneration in osteoarthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23473975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5' UTR of GDF5 with osteoarthritis susceptibility

1 reference

https://pubmed.ncbi.nlm.nih.gov/23473975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.JOCA.2013.02.659

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

31 October 2017

ResearchGate publication ID

0 references

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