(Q42450535)

English

Neurodegeneration in Striatum Induced by the Mitochondrial Toxin 3-Nitropropionic Acid: Role of Matrix Metalloproteinase-9 in Early Blood-Brain Barrier Disruption?

scientific article published on September 24, 2003

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14507973%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

Neurodegeneration in striatum induced by the mitochondrial toxin 3-nitropropionic acid: role of matrix metalloproteinase-9 in early blood-brain barrier disruption? (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14507973%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

Neurodegeneration in Striatum Induced by the Mitochondrial Toxin 3-Nitropropionic Acid: Role of Matrix Metalloproteinase-9 in Early Blood-Brain Barrier Disruption? (English)

1 reference

10.1523/JNEUROSCI.23-25-08733.2003

https://api.crossref.org/works/10.1523/JNEUROSCI.23-25-08733.2003

14 March 2024

blood–brain barrier

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

neurodegeneration

1 reference

based on heuristic

inferred from title

author name string

Yvan Gasche

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14507973%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

Susanna Grzeschik

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14507973%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

Jean-Christophe Copin

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14507973%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

Gyung W. Kim

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14507973

14 March 2024

Carolina M. Maier

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14507973

14 March 2024

Pak H. Chan

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14507973

14 March 2024

language of work or name

0 references

publication date

1 September 2003

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14507973%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

24 September 2003

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14507973

14 March 2024

full work available at URL

https://www.jneurosci.org/content/jneuro/23/25/8733.full.pdf

Portable Document Format

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14507973

14 March 2024

http://www.jneurosci.org/cgi/content/abstract/23/25/8733

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14507973

14 March 2024

https://europepmc.org/articles/PMC6740428

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14507973

14 March 2024

https://europepmc.org/articles/PMC6740428?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14507973

14 March 2024

https://doi.org/10.1523/jneurosci.23-25-08733.2003

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14507973

14 March 2024

https://syndication.highwire.org/content/doi/10.1523/JNEUROSCI.23-25-08733.2003

1 reference

10.1523/JNEUROSCI.23-25-08733.2003

https://api.crossref.org/works/10.1523/JNEUROSCI.23-25-08733.2003

14 March 2024

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14507973%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

23

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14507973%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

25

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14507973%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

8733-8742

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14507973%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astrocytes enhance radical defence in capillary endothelial cells constituting the blood-brain barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early appearance of activated matrix metalloproteinase-9 after focal cerebral ischemia in mice: a possible role in blood-brain barrier dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early appearance of activated matrix metalloproteinase-9 and blood-brain barrier disruption in mice after focal cerebral ischemia and reperfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Excitotoxicity is required for induction of oxidative stress and apoptosis in mouse striatum by the mitochondrial toxin, 3-nitropropionic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of copper and zinc superoxide dismutase in transgenic mice prevents the induction and activation of matrix metalloproteinases after cold injury-induced brain trauma

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The striatum is the most vulnerable region in the brain to mitochondrial energy compromise: a hypothesis to explain its specific vulnerability

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of blood vessels in producing pathological changes in the brain with Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Energetics in the pathogenesis of neurodegenerative diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role for matrix metalloproteinase 9 after focal cerebral ischemia: effects of gene knockout and enzyme inhibition with BB-94.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of oxidative stress and caspase-3 in cortical infarction after photothrombotic ischemia in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress and neuronal DNA fragmentation mediate age-dependent vulnerability to the mitochondrial toxin, 3-nitropropionic acid, in the mouse striatum

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of oxidative stress by homocyst(e)ine impairs endothelial function

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cytosolic antioxidant, copper/zinc superoxide dismutase, attenuates blood-brain barrier disruption and oxidative cellular injury after photothrombotic cortical ischemia in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular physiology and pathophysiology of tight junctions in the blood-brain barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinase inhibition prevents oxidative stress-associated blood-brain barrier disruption after transient focal cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of copper/zinc superoxide dismutase in transgenic rats protects vulnerable neurons against ischemic damage by blocking the mitochondrial pathway of caspase activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Manganese superoxide dismutase deficiency exacerbates cerebral infarction after focal cerebral ischemia/reperfusion in mice: implications for the production and role of superoxide radicals

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of superoxide in excitotoxicity and DNA fragmentation in striatal vulnerability in mice after treatment with the mitochondrial toxin, 3-nitropropionic acid.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

S-nitrosylation of matrix metalloproteinases: signaling pathway to neuronal cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the mitogen activated protein kinase extracellular signal-regulated kinase 1 and 2 by the nitric oxide-cGMP-cGMP-dependent protein kinase axis regulates the expression of matrix metalloproteinase 13 in vascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blood-brain barrier disruption and matrix metalloproteinase-9 expression during reperfusion injury: mechanical versus embolic focal ischemia in spontaneously hypertensive rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of cold injury-induced trauma in manganese superoxide dismutase-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alternative excitotoxic hypotheses

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular changes in the spinal cord in N-methyl-D-aspartate-induced excitotoxicity: morphological and permeability studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intraventricular infusion of N-methyl-D-aspartate. 1. Acute blood-brain barrier consequences.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of Neutral Proteinases from Alzheimer-Affected and Control Brain Specimens: Identification of Calcium-Dependent Metalloproteinases from the Hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum amyloid P in Alzheimer's disease. Implications for dysfunction of the blood-brain barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

3-Nitropropionic acid-exogenous animal neurotoxin and possible human striatal toxin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cold-induced brain edema and infarction are reduced in transgenic mice overexpressing CuZn-Superoxide dismutase

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An integrative hypothesis concerning the pathogenesis and progression of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation of morphologic brain lesions with physiologic alterations and blood-brain barrier impairment in 3-nitropropionic acid toxicity in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of succinate dehydrogenase by 3-nitropropionate

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain injury, edema, and vascular permeability changes induced by oxygen-derived free radicals

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Basal ganglia degeneration, myelin alterations, and enzyme inhibition induced in mice by the plant toxin 3-nitropropanoic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

3-Nitropropionic acid neurotoxicity is attenuated in copper/zinc superoxide dismutase transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aging, energy, and oxidative stress in neurodegenerative diseases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronically administered 3-nitropropionic acid induces striatal lesions attributed to dysfunction of the blood-brain barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of oxygen radicals and IL-6 in IL-1-dependent cartilage matrix degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress, glutamate, and neurodegenerative disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative zymography: detection of picogram quantities of gelatinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate-induced disruption of the blood-brain barrier in rats. Role of nitric oxide.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased production of matrix metalloproteinases in enriched astrocyte and mixed hippocampal cultures treated with beta-amyloid peptides.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinases in the neocortex and spinal cord of amyotrophic lateral sclerosis patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMDA- and endothelin-1-induced increases in blood-brain barrier permeability quantitated with Lucifer yellow.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of oxidative stress in 3-nitropropionic acid neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The influence of oxygen free radicals on the permeability of the monolayer of cultured brain endothelial cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Delayed dystonia with striatal CT lucencies induced by a mycotoxin (3-nitropropionic acid)

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis in the striatum of rats following intraperitoneal injection of 3-nitropropionic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of CuZn-superoxide dismutase activity exacerbates neuronal cell injury and edema formation after transient focal cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute 3-nitropropionic acid intoxication induces striatal astrocytic cell death and dysfunction of the blood-brain barrier: involvement of dopamine toxicity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

3-Nitropropionic acid increases the intracellular Ca2+ in cultured astrocytes by reverse operation of the Na+-Ca2+ exchanger.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zymographic measurement of gelatinase activity in brain tissue after detergent extraction and affinity-support purification.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinases and diseases of the CNS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

3-Nitropropionic acid exacerbates N-methyl-D-aspartate toxicity in striatal culture by multiple mechanisms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinase expression increases after cerebral focal ischemia in rats: inhibition of matrix metalloproteinase-9 reduces infarct size

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astrocytes are more vulnerable than neurons to cellular Ca2+ overload induced by a mitochondrial toxin, 3-nitropropionic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrix metalloproteinases and TIMPs are associated with blood-brain barrier opening after reperfusion in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of SOD1 in transgenic rats protects vulnerable neurons against ischemic damage after global cerebral ischemia and reperfusion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased expression of bcl-2 and bcl-x mRNA coincides with apoptosis following intracerebral administration of 3-nitropropionic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Critical evaluation of the use of hydroethidine as a measure of superoxide anion radical

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer-type lesions in Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/14507973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.23-25-08733.2003

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14507973%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14507973%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14507973%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

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