(Q42451739)

English

Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stress

scientific article published on 14 July 2010

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scholarly article

1 reference

Europe PubMed Central

31 October 2017

Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stress (English)

1 reference

Europe PubMed Central

31 October 2017

endoplasmic reticulum

0 references

0 references

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Keisuke Yamamoto

1

1 reference

Europe PubMed Central

31 October 2017

Kazuna Takahara

2

1 reference

Europe PubMed Central

31 October 2017

Seiichi Oyadomari

3

1 reference

Europe PubMed Central

31 October 2017

Tetsuya Okada

4

1 reference

Europe PubMed Central

31 October 2017

Takashi Sato

5

1 reference

Europe PubMed Central

31 October 2017

Akihiro Harada

6

1 reference

Europe PubMed Central

31 October 2017

Kazutoshi Mori

7

1 reference

Europe PubMed Central

31 October 2017

publication date

14 July 2010

1 reference

Europe PubMed Central

31 October 2017

Molecular Biology of the Cell

1 reference

Europe PubMed Central

31 October 2017

21

1 reference

Europe PubMed Central

31 October 2017

2975-2986

1 reference

Europe PubMed Central

31 October 2017

17

1 reference

Europe PubMed Central

31 October 2017

UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

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Regulation of hepatic lipogenesis by the transcription factor XBP1

1 reference

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Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice

1 reference

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Transcriptional regulation of peroxisome proliferator-activated receptors and liver X receptors.

1 reference

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The blind men 'see' the elephant-the many faces of fatty liver disease

1 reference

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28 May 2018

Nonalcoholic fatty liver disease and mitochondrial dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

28 May 2018

ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress

1 reference

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28 May 2018

PPARalpha and dyslipidemia

1 reference

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28 May 2018

The role of p58IPK in protecting the stressed endoplasmic reticulum

1 reference

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28 May 2018

Signal integration in the endoplasmic reticulum unfolded protein response

1 reference

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Diversity of endotoxin and its impact on pathogenesis

1 reference

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28 May 2018

Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload

1 reference

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28 May 2018

Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response.

1 reference

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28 May 2018

Molecular chaperones and protein quality control

1 reference

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28 May 2018

Lipid metabolism and liver inflammation. II. Fatty liver disease and fatty acid oxidation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

28 May 2018

Lipid droplets: a unified view of a dynamic organelle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

28 May 2018

Mouse models in non-alcoholic fatty liver disease and steatohepatitis research.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

28 May 2018

Lipid metabolism and liver inflammation. I. Hepatic fatty acid uptake: possible role in steatosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

28 May 2018

Protein synthesis upon acute nutrient restriction relies on proteasome function

1 reference

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28 May 2018

Genetic interactions due to constitutive and inducible gene regulation mediated by the unfolded protein response in C. elegans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

28 May 2018

The mammalian unfolded protein response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

28 May 2018

Nonalcoholic fatty liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

28 May 2018

Mechanisms of non-alcoholic steatohepatitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

28 May 2018

Molecular mediators of hepatic steatosis and liver injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

28 May 2018

Activation of mammalian unfolded protein response is compatible with the quality control system operating in the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

28 May 2018

HSP47 as a collagen-specific molecular chaperone: function and expression in normal mouse development

1 reference

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28 May 2018

Dynamic and regulated association of caveolin with lipid bodies: modulation of lipid body motility and function by a dominant negative mutant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

28 May 2018

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

28 May 2018

A serine protease inhibitor prevents endoplasmic reticulum stress-induced cleavage but not transport of the membrane-bound transcription factor ATF6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

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Nonalcoholic steatohepatitis: what we know in the new millennium

1 reference

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28 May 2018

Pathogenesis of steatohepatitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

28 May 2018

The surface of lipid droplets is a phospholipid monolayer with a unique Fatty Acid composition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

28 May 2018

ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

28 May 2018

Distinct roles of activating transcription factor 6 (ATF6) and double-stranded RNA-activated protein kinase-like endoplasmic reticulum kinase (PERK) in transcription during the mammalian unfolded protein response

1 reference

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Complexity in the secretory pathway: the assembly and secretion of apolipoprotein B-containing lipoproteins

1 reference

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Retro-translocation of proteins from the endoplasmic reticulum into the cytosol

1 reference

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Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways

1 reference

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Identification of the G13 (cAMP-response-element-binding protein-related protein) gene product related to activating transcription factor 6 as a transcriptional activator of the mammalian unfolded protein response

1 reference

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ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929991

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Endoplasmic reticulum stress-induced formation of transcription factor complex ERSF including NF-Y (CBF) and activating transcription factors 6alpha and 6beta that activates the mammalian unfolded protein response

1 reference

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ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response

1 reference

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Tripartite management of unfolded proteins in the endoplasmic reticulum

1 reference

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Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation

1 reference

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HRD gene dependence of endoplasmic reticulum-associated degradation

1 reference

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Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

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Protein disulfide isomerase: the multifunctional redox chaperone of the endoplasmic reticulum

1 reference

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28 May 2018

Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress

1 reference

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Degradation of newly synthesized apolipoprotein B-100 in a pre-Golgi compartment

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CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription

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1 reference

https://pubmed.ncbi.nlm.nih.gov/20631254

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CuZn-SOD deficiency causes ApoB degradation and induces hepatic lipid accumulation by impaired lipoprotein secretion in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20631254

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based on heuristic

inferred from PubMed ID database lookup

Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1

1 reference

https://pubmed.ncbi.nlm.nih.gov/20631254

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ATF6 is a transcription factor specializing in the regulation of quality control proteins in the endoplasmic reticulum

1 reference

https://pubmed.ncbi.nlm.nih.gov/20631254

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1091/MBC.E09-02-0133

1 reference

Europe PubMed Central

31 October 2017

1 reference

Europe PubMed Central

31 October 2017

1 reference

Europe PubMed Central

31 October 2017

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