(Q42455250)

English

Prolonged increase of plasma non-esterified fatty acids fully abolishes the stimulatory effect of 24 hours of moderate hyperglycaemia on insulin sensitivity and pancreatic beta-cell function in obese men.

scientific article published on 8 January 2004

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

Prolonged increase of plasma non-esterified fatty acids fully abolishes the stimulatory effect of 24 hours of moderate hyperglycaemia on insulin sensitivity and pancreatic beta-cell function in obese men. (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

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1 reference

based on heuristic

inferred from title

author name string

N Leung

1

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

T Sakaue

2

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

A Carpentier

3

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

K Uffelman

4

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

A Giacca

5

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

G F Lewis

6

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

publication date

8 January 2004

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

47

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

204-213

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

https://scigraph.springernature.com/pub.10.1007/s00125-003-1301-7

0 references

Chronic hyperglycemia is associated with impaired glucose influence on insulin secretion. A study in normal rats using chronic in vivo glucose infusions

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The defective glucose sensitivity of the B cell in non insulin dependent diabetes. Improvement after twenty hours of normoglycaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Seminars in Medicine of the Beth Israel Hospital, Boston. Non-insulin-dependent diabetes mellitus - a genetically programmed failure of the beta cell to compensate for insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lowering fatty acids potentiates acute insulin response in first degree relatives of people with type II diabetes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin secretion and clearance during low-dose graded glucose infusion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of chronic hyperglycemia on in vivo insulin secretion in partially pancreatectomized rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

No glucotoxicity after 53 hours of 6.0 mmol/l hyperglycaemia in normal man.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-cell dysfunction induced by chronic hyperglycemia. Current ideas on mechanism of impaired glucose-induced insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of sustained physiologic hyperinsulinaemia and hyperglycaemia on insulin secretion and insulin sensitivity in man.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolonged elevation of plasma free fatty acids impairs pancreatic beta-cell function in obese nondiabetic humans but not in individuals with type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin release

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overnight lowering of free fatty acids with Acipimox improves insulin resistance and glucose tolerance in obese diabetic and nondiabetic subjects.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term exposure of beta-INS cells to high glucose concentrations increases anaplerosis, lipogenesis, and lipogenic gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diabetes mellitus in the Pima Indians: incidence, risk factors and pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Islet Secretion in a New Experimental Model for Non-insulin-dependent Diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of insulin gene expression by long-term exposure of pancreatic beta cells to palmitate is dependent on the presence of a stimulatory glucose concentration

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipotoxicity of the pancreatic beta-cell is associated with glucose-dependent esterification of fatty acids into neutral lipids

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-chain fatty acids inhibit acetyl-CoA carboxylase gene expression in the pancreatic beta-cell line INS-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Minireview: Secondary beta-cell failure in type 2 diabetes--a convergence of glucotoxicity and lipotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Short-term hyperglycemia and hyperinsulinemia improve insulin action but do not alter glucose action in normal humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Banting lecture 1990. Beta-cells in type II diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acids and insulin secretion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction by glucose of genes coding for glycolytic enzymes in a pancreatic beta-cell line (INS-1).

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antecedent hyperglycemia, not hyperlipidemia, is associated with increased islet triacylglycerol content and decreased insulin gene mRNA level in Zucker diabetic fatty rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-cell dysfunction in hyperglycaemic rat models: recovery of glucose-induced insulin secretion with lowering of the ambient glucose level

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of increased plasma non-esterified fatty acids (NEFAs) on arginine-stimulated insulin secretion in obese humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose regulates acetyl-CoA carboxylase gene expression in a pancreatic beta-cell line (INS-1).

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estimation of insulin secretion rates from C-peptide levels. Comparison of individual and standard kinetic parameters for C-peptide clearance

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose clamp technique: a method for quantifying insulin secretion and resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute enhancement of insulin secretion by FFA in humans is lost with prolonged FFA elevation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute elevation of NEFA causes hyperinsulinemia without effect on insulin secretion rate in healthy human subjects.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathogenesis of NIDDM. A balanced overview

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acids rapidly induce the carnitine palmitoyltransferase I gene in the pancreatic beta-cell line INS-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Malonyl-CoA signaling, lipid partitioning, and glucolipotoxicity: role in beta-cell adaptation and failure in the etiology of diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin resistance or insulin deficiency. Which is the primary cause of NIDDM?

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lilly Lecture 1994. The beta-cell in diabetes: from molecular genetics to clinical research

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired insulin secretion associated with near normoglycemia. Study in normal rats with 96-h in vivo glucose infusions

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of prolonged glucose infusion on insulin secretion, clearance, and action in normal subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of non-esterified fatty acids in the deterioration of glucose tolerance in Caucasian subjects: results of the Paris Prospective Study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin treatment improves glucose-induced insulin release in rats with NIDDM induced by streptozocin

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acids, lipotoxicity and insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/14712348

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00125-003-1301-7

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 October 2017

ResearchGate publication ID

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