(Q42458279)

English

Differential roles of phosphatidylserine, PtdIns(4,5)P2, and PtdIns(3,4,5)P3 in plasma membrane targeting of C2 domains. Molecular dynamics simulation, membrane binding, and cell translocation studies of the PKCalpha C2 domain

scientific article published on 11 July 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

1 November 2017

Differential roles of phosphatidylserine, PtdIns(4,5)P2, and PtdIns(3,4,5)P3 in plasma membrane targeting of C2 domains. Molecular dynamics simulation, membrane binding, and cell translocation studies of the PKCalpha C2 domain (English)

1 reference

Europe PubMed Central

PMC publication ID

1 November 2017

author name string

Debasis Manna

1

1 reference

Europe PubMed Central

PMC publication ID

1 November 2017

Nitin Bhardwaj

2

1 reference

Europe PubMed Central

PMC publication ID

1 November 2017

Mohsin S Vora

3

1 reference

Europe PubMed Central

PMC publication ID

1 November 2017

Robert V Stahelin

4

1 reference

Europe PubMed Central

PMC publication ID

1 November 2017

Hui Lu

5

1 reference

Europe PubMed Central

PMC publication ID

1 November 2017

Wonhwa Cho

6

1 reference

Europe PubMed Central

PMC publication ID

1 November 2017

language of work or name

0 references

publication date

11 July 2008

1 reference

Europe PubMed Central

PMC publication ID

1 November 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

1 November 2017

283

1 reference

Europe PubMed Central

PMC publication ID

1 November 2017

38

1 reference

Europe PubMed Central

PMC publication ID

1 November 2017

26047-26058

1 reference

Europe PubMed Central

PMC publication ID

1 November 2017

Membrane phosphatidylserine regulates surface charge and protein localization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533782

28 May 2018

Mechanistic basis of differential cellular responses of phosphatidylinositol 3,4-bisphosphate- and phosphatidylinositol 3,4,5-trisphosphate-binding pleckstrin homology domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533782

28 May 2018

Mechanism of specific membrane targeting by C2 domains: localized pools of target lipids enhance Ca2+ affinity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533782

28 May 2018

PI(3,4,5)P3 and PI(4,5)P2 lipids target proteins with polybasic clusters to the plasma membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533782

28 May 2018

Direct observation of Bin/amphiphysin/Rvs (BAR) domain-induced membrane curvature by means of molecular dynamics simulations

1 reference

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28 May 2018

The C2 domain of PKCalpha is a Ca2+ -dependent PtdIns(4,5)P2 sensing domain: a new insight into an old pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533782

28 May 2018

Membrane binding and subcellular targeting of C2 domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533782

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Building signaling complexes at the membrane

1 reference

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Automatic atom type and bond type perception in molecular mechanical calculations

1 reference

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28 May 2018

Plasma membrane phosphoinositide organization by protein electrostatics

1 reference

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The mechanism of membrane targeting of human sphingosine kinase 1.

1 reference

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28 May 2018

Specific translocation of protein kinase Calpha to the plasma membrane requires both Ca2+ and PIP2 recognition by its C2 domain

1 reference

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28 May 2018

Scalable molecular dynamics with NAMD

1 reference

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28 May 2018

The Amber biomolecular simulation programs

1 reference

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28 May 2018

Metabolism and functions of phosphatidylserine

1 reference

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28 May 2018

An inducible translocation strategy to rapidly activate and inhibit small GTPase signaling pathways

1 reference

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28 May 2018

Membrane-protein interactions in cell signaling and membrane trafficking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533782

28 May 2018

Use of EPR power saturation to analyze the membrane-docking geometries of peripheral proteins: applications to C2 domains

1 reference

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28 May 2018

Molecular dynamics simulation study of the interaction of trehalose with lipid membranes

1 reference

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28 May 2018

Molecular dynamics simulation of lipid reorientation at bilayer edges.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533782

28 May 2018

Development and testing of a general amber force field

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533782

28 May 2018

Mechanism of diacylglycerol-induced membrane targeting and activation of protein kinase Cdelta

1 reference

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28 May 2018

The C2 domains of synaptotagmin--partners in exocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533782

28 May 2018

Molecular dynamics simulation of a palmitoyl-oleoyl phosphatidylserine bilayer with Na+ counterions and NaCl.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533782

28 May 2018

Contrasting membrane interaction mechanisms of AP180 N-terminal homology (ANTH) and epsin N-terminal homology (ENTH) domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533782

28 May 2018

C2 domain of protein kinase C alpha: elucidation of the membrane docking surface by site-directed fluorescence and spin labeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533782

28 May 2018

The molecular basis of differential subcellular localization of C2 domains of protein kinase C-alpha and group IVa cytosolic phospholipase A2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533782

28 May 2018

A new phosphatidylinositol 4,5-bisphosphate-binding site located in the C2 domain of protein kinase Calpha.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533782

28 May 2018

Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin

1 reference

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28 May 2018

Fast, efficient generation of high-quality atomic charges. AM1-BCC model: II. Parameterization and validation

1 reference

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28 May 2018

PIP(2) and proteins: interactions, organization, and information flow

1 reference

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28 May 2018

Molecular dynamics simulation of proton transport near the surface of a phospholipid membrane

1 reference

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28 May 2018

Electrostatic control of the membrane targeting of C2 domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533782

28 May 2018

Identification of the phosphatidylserine binding site in the C2 domain that is important for PKC alpha activation and in vivo cell localization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533782

28 May 2018

Membrane binding assays for peripheral proteins.

1 reference

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28 May 2018

Membrane targeting by C1 and C2 domains

1 reference

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28 May 2018

Subcellular targeting by membrane lipids

1 reference

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1 reference

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1 reference

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1 reference

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Ca(2+) bridges the C2 membrane-binding domain of protein kinase Calpha directly to phosphatidylserine

1 reference

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1 reference

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1 reference

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28 May 2018

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1 reference

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MeTaDoR: a comprehensive resource for membrane targeting domains and their host proteins.

1 reference

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1 reference

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Roles of calcium ions in the membrane binding of C2 domains.

1 reference

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16 August 2018

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1 reference

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1 reference

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21 January 2018

The C2 domains of classical PKCs are specific PtdIns(4,5)P2-sensing domains with different affinities for membrane binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/18621733

12 December 2020

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10.1074/JBC.M802617200

1 reference

Europe PubMed Central

PMC publication ID

1 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

1 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

1 November 2017

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