(Q42462619)

1 November 2017

title

IGFBP-3 activates TGF-beta receptors and directly inhibits growth in human intestinal smooth muscle cells (English)

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1 November 2017

John F Kuemmerle

1

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1 November 2017

Karnam S Murthy

series ordinal

2

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1 November 2017

Jennifer G Bowers

series ordinal

3

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1 November 2017

publication date

3 June 2004

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American Journal of Physiology - Gastrointestinal and Liver Physiology

1 November 2017

published in

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1 November 2017

volume

287

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1 November 2017

issue

4

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1 November 2017

page(s)

G795-802

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Signalling pathways involved in antiproliferative effects of IGFBP-3: a review

1 November 2017

cites work

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

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Signaling through the Smad pathway by insulin-like growth factor-binding protein-3 in breast cancer cells. Relationship to transforming growth factor-beta 1 signaling.

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Growth inhibition by insulin-like growth factor-binding protein-3 in T47D breast cancer cells requires transforming growth factor-beta (TGF-beta ) and the type II TGF-beta receptor

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Cellular growth inhibition by IGFBP-3 and TGF-beta1 requires LRP-1

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IGFBP-3 mediates TGF beta 1 proliferative response in colon cancer cells

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Reduced serum insulin-like growth factor-1 (IGF-1) and IGF-binding protein-3 levels in adults with inflammatory bowel disease.

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Coupling of the insulin-like growth factor-I receptor tyrosine kinase to Gi2 in human intestinal smooth muscle: Gbetagamma -dependent mitogen-activated protein kinase activation and growth

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Insulin-like growth factor-binding protein-5 (IGFBP-5) stimulates growth and IGF-I secretion in human intestinal smooth muscle by Ras-dependent activation of p38 MAP kinase and Erk1/2 pathways

21 January 2018

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IGF-I stimulates human intestinal smooth muscle cell growth by regulation of G1phase cell cycle proteins

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Inflammation location, but not type, determines the increase in TGF-beta1 and IGF-1 expression and collagen deposition in IBD intestine

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A non-IGF binding mutant of IGFBP-3 modulates cell function in breast epithelial cells

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Insulin-like growth factor (IGF)-binding protein-3 induces apoptosis and mediates the effects of transforming growth factor-beta1 on programmed cell death through a p53- and IGF-independent mechanism

21 January 2018

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21 January 2018

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Insulin-like growth factor-binding protein (IGFBP)-3 and IGFBP-5 share a common nuclear transport pathway in T47D human breast carcinoma cells

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Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice

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Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling

21 January 2018

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Antiproliferative effects of insulin-like growth factor-binding protein-3 in mesenchymal chondrogenic cell line RCJ3.1C5.18. relationship to differentiation stage

21 January 2018

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Characterization of the MADH2/Smad2 gene, a human Mad homolog responsible for the transforming growth factor-beta and activin signal transduction pathway

21 January 2018

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Selective expression of vasoactive intestinal peptide (VIP)2/pituitary adenylate cyclase-activating polypeptide (PACAP)3 receptors in rabbit and guinea pig gastric and tenia coli smooth muscle cells

21 January 2018

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Characterization of the inhibition of DNA synthesis in proliferating mink lung epithelial cells by insulin-like growth factor binding protein-3.

21 January 2018

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Normal growth and development in the absence of hepatic insulin-like growth factor I

21 January 2018

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21 January 2018

Identifiers

DOI

10.1152/AJPGI.00009.2004

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1 November 2017

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