(Q42464925)

1 November 2017

Mechanism of constitutive activation of the AT1 receptor: influence of the size of the agonist switch binding residue Asn(111). (English)

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1 November 2017

Y H Feng

1

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1 November 2017

S Miura

series ordinal

2

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1 November 2017

A Husain

series ordinal

3

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1 November 2017

S S Karnik

series ordinal

4

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1 November 2017

language of work or name

English

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publication date

1 November 1998

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1 November 2017

8

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inferred from page(s)

published in

Biochemistry

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1 November 2017

37

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1 November 2017

45

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1 November 2017

15791-15798

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The probable arrangement of the helices in G protein-coupled receptors.

1 November 2017

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12 December 2020

Mutation of Asn111 in the third transmembrane domain of the AT1A angiotensin II receptor induces its constitutive activation.

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12 December 2020

Is there a 'lock' for all agonist 'keys' in 7TM receptors?

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12 December 2020

Isolation of a cDNA encoding the vascular type-1 angiotensin II receptor.

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12 December 2020

Polar residues in the transmembrane domains of the type 1 angiotensin II receptor are required for binding and coupling. Reconstitution of the binding site by co-expression of two deficient mutants.

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12 December 2020

The conformational change responsible for AT1 receptor activation is dependent upon two juxtaposed asparagine residues on transmembrane helices III and VII.

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12 December 2020

Additivity of mutational effects in proteins

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12 December 2020

Pharmacological proteus?

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12 December 2020

Structural instability of a constitutively active G protein-coupled receptor. Agonist-independent activation due to conformational flexibility

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12 December 2020

Monoclonal antibodies to purified muscarinic receptor display agonist-like activity

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12 December 2020

Molecular determinants of peptide and non-peptide binding to the AT1 receptor

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12 December 2020

The active state of the AT1 angiotensin receptor is generated by angiotensin II induction

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12 December 2020

A computer modeling postulated mechanism for angiotensin II receptor activation

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12 December 2020

Rhodopsin, photoreceptor of the rod cell. An emerging pattern for structure and function

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12 December 2020

Tetrazole and carboxylate groups of angiotensin receptor antagonists bind to the same subsite by different mechanisms

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12 December 2020

The docking of Arg2 of angiotensin II with Asp281 of AT1 receptor is essential for full agonism

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12 December 2020

Cloning and expression of a complementary DNA encoding a bovine adrenal angiotensin II type-1 receptor.

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12 December 2020

Activation of the alpha1b-adrenergic receptor is initiated by disruption of an interhelical salt bridge constraint

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12 December 2020

Identification of amino acid residues of rat angiotensin II receptor for ligand binding by site directed mutagenesis

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12 December 2020

Molecular cloning of a novel angiotensin II receptor isoform involved in phosphotyrosine phosphatase inhibition

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12 December 2020

Structure and function of G protein-coupled receptors

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12 December 2020

G protein-coupled receptor structure and function: the impact of disease-causing mutations

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12 December 2020

Autoimmunity in idiopathic dilated cardiomyopathy. Characterization of antibodies against the beta 1-adrenoceptor with positive chronotropic effect

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12 December 2020

Expression cloning of type 2 angiotensin II receptor reveals a unique class of seven-transmembrane receptors

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12 December 2020

Response of a protein structure to cavity-creating mutations and its relation to the hydrophobic effect

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12 December 2020

Thrombin receptor activating mutations. Alteration of an extracellular agonist recognition domain causes constitutive signaling

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12 December 2020

A thermodynamic scale for the helix-forming tendencies of the commonly occurring amino acids

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12 December 2020

Constitutively active mutants of rhodopsin

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12 December 2020

Interaction of Phe8 of angiotensin II with Lys199 and His256 of AT1 receptor in agonist activation

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12 December 2020

Identifiers

DOI

10.1021/BI980863T

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1 November 2017

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