(Q42473196)

English

Chemopreventive effect of N-(2-cyclohexyloxy-4-nitrophenyl)methane sulfonamide (NS-398), a selective cyclooxygenase-2 inhibitor, in rat colon carcinogenesis induced by azoxymethane

scientific article published on April 1999

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scholarly article

1 reference

Europe PubMed Central

15 June 2018

http://europepmc.org/abstract/PMC/5926081

Chemopreventive effect of N-(2-cyclohexyloxy-4-nitrophenyl)methane sulfonamide (NS-398), a selective cyclooxygenase-2 inhibitor, in rat colon carcinogenesis induced by azoxymethane (English)

1 reference

Europe PubMed Central

15 June 2018

http://europepmc.org/abstract/PMC/5926081

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

N Yoshimi

1

1 reference

Europe PubMed Central

15 June 2018

http://europepmc.org/abstract/PMC/5926081

M Shimizu

2

1 reference

Europe PubMed Central

15 June 2018

http://europepmc.org/abstract/PMC/5926081

K Matsunaga

3

1 reference

Europe PubMed Central

15 June 2018

http://europepmc.org/abstract/PMC/5926081

Y Yamada

4

1 reference

Europe PubMed Central

15 June 2018

http://europepmc.org/abstract/PMC/5926081

K Fujii

5

1 reference

Europe PubMed Central

15 June 2018

http://europepmc.org/abstract/PMC/5926081

A Hara

6

1 reference

Europe PubMed Central

15 June 2018

http://europepmc.org/abstract/PMC/5926081

H Mori

7

1 reference

Europe PubMed Central

15 June 2018

http://europepmc.org/abstract/PMC/5926081

publication date

1 April 1999

1 reference

Europe PubMed Central

15 June 2018

http://europepmc.org/abstract/PMC/5926081

number of pages

7

1 reference

based on heuristic

inferred from page(s)

Japanese Journal of Cancer Research

1 reference

Europe PubMed Central

15 June 2018

http://europepmc.org/abstract/PMC/5926081

90

1 reference

Europe PubMed Central

15 June 2018

http://europepmc.org/abstract/PMC/5926081

406-412

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Europe PubMed Central

15 June 2018

http://europepmc.org/abstract/PMC/5926081

4

1 reference

Europe PubMed Central

15 June 2018

http://europepmc.org/abstract/PMC/5926081

NS398, a selective cyclooxygenase-2 inhibitor, induces apoptosis and down-regulates bcl-2 expression in LNCaP cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 June 2018

Cyclooxygenase regulates angiogenesis induced by colon cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 June 2018

Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, against colon carcinogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 June 2018

Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 June 2018

G1 delay in cells overexpressing prostaglandin endoperoxide synthase-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 June 2018

Differential growth inhibition by the aspirin metabolite salicylate in human colorectal tumor cell lines: enhanced apoptosis in carcinoma and in vitro-transformed adenoma relative to adenoma relative to adenoma cell lines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 June 2018

NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 June 2018

Inhibitory effect of aspirin on azoxymethane-induced colon carcinogenesis in F344 rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 June 2018

Cloning two isoforms of rat cyclooxygenase: differential regulation of their expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 June 2018

Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 June 2018

Expression of cyclooxygenase-1 and -2 in human colorectal cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 June 2018

Cyclooxygenase gene expression in inflammation and angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 June 2018

Concentrations of prostaglandin endoperoxide synthase and prostaglandin I2 synthase in the endothelium and smooth muscle of bovine aorta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 June 2018

Observation and quantification of aberrant crypts in the murine colon treated with a colon carcinogen: preliminary findings

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 June 2018

Participation of high-risk subjects in colon cancer screening

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 June 2018

Inhibitory effect of the non-steroidal anti-inflammatory drug, indomethacin on the naturally occurring carcinogen, 1-hydroxyanthraquinone in male ACI/N rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 June 2018

Prostaglandin endoperoxide synthase: structure and catalysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 June 2018

TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 June 2018

Aspirin use and reduced risk of fatal colon cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 June 2018

Colonoscopic screening for neoplasms in asymptomatic first-degree relatives of colon cancer patients. A controlled, prospective study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 June 2018

Cell kinetic analysis of the mucosal epithelium and assay of ornithine decarboxylase activity during the process of 1-hydroxyanthraquinone-induced large bowel carcinogenesis in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 June 2018

Human cyclooxygenase-2 cDNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 June 2018

Effects of nonsteroidal anti-inflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandin-independent pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 June 2018

Inhibitory effect of NS-398, a selective cyclooxygenase-2 inhibitor, on azoxymethane-induced aberrant crypt foci in colon carcinogenesis of F344 rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 June 2018

Apoptosis induced by NS-398, a selective cyclooxygenase-2 inhibitor, in human colorectal cancer cell lines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 June 2018

Suppressive effects of nimesulide, a selective inhibitor of cyclooxygenase-2, on azoxymethane-induced colon carcinogenesis in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 August 2018

Suppression of intestinal polyp development by nimesulide, a selective cyclooxygenase-2 inhibitor, in Min mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 August 2018

Sulindac suppresses tumorigenesis in the Min mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 August 2018

Suppression of azoxymethane-induced aberrant crypt foci in rat colon by nimesulide, a selective inhibitor of cyclooxygenase 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 August 2018

Perspectives on cancer in Japan and the United States.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 August 2018

Chemoprevention of colon carcinogenesis by sulindac, a nonsteroidal anti-inflammatory agent.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 August 2018

The mRNA overexpression of inflammatory enzymes, phospholipase A2 and cyclooxygenase, in the large bowel mucosa and neoplasms of F344 rats treated with naturally occurring carcinogen, 1-hydroxyanthraquinone.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5926081

16 August 2018

Increased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/10363578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sulindac for polyposis of the colon

1 reference

https://pubmed.ncbi.nlm.nih.gov/10363578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/10363578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low-dose aspirin and incidence of colorectal tumors in a randomized trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/10363578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemopreventive effects of nimesulide, a selective cyclooxygenase-2 inhibitor, on the development of rat urinary bladder carcinomas initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/10363578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory effects of magnesium hydroxide on c-myc expression and cell proliferation induced by methylazoxymethanol acetate in rat colon

1 reference

https://pubmed.ncbi.nlm.nih.gov/10363578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective inhibition of NS-398 on prostanoid production in inflamed tissue in rat carrageenan-air-pouch inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10363578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morphogenesis of chemically induced neoplasms of the colon and small intestine in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/10363578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A structural feature of N-[2-(cyclohexyloxy)-4-nitrophenyl] methanesulfonamide (NS-398) that governs its selectivity and affinity for cyclooxygenase 2 (COX2)

1 reference

https://pubmed.ncbi.nlm.nih.gov/10363578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of selective cyclooxygenase-2 inhibitors on alkaline secretory and mucosal ulcerogenic responses in rat duodenum

1 reference

https://pubmed.ncbi.nlm.nih.gov/10363578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemoprevention of spontaneous intestinal adenomas in the Apc Min mouse model by the nonsteroidal anti-inflammatory drug piroxicam

1 reference

https://pubmed.ncbi.nlm.nih.gov/10363578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/10363578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of NS-398, a new nonsteroidal anti-inflammatory agent, on gastric ulceration and acid secretion in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/10363578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclooxygenase-2 inhibitors suppress the growth of gastric cancer xenografts via induction of apoptosis in nude mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10363578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of cyclooxygenase-2 inhibitor for potential chemopreventive properties in colon carcinogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10363578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1349-7006.1999.TB00762.X

1 reference

Europe PubMed Central

15 June 2018

http://europepmc.org/abstract/PMC/5926081

1 reference

Europe PubMed Central

15 June 2018

http://europepmc.org/abstract/PMC/5926081

1 reference

Europe PubMed Central

15 June 2018

http://europepmc.org/abstract/PMC/5926081

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