(Q42474271)

English

Activation of key profibrotic mechanisms in transgenic fibroblasts expressing kinase-deficient type II Transforming growth factor-{beta} receptor (T{beta}RII{delta}k).

scientific article published on 11 February 2005

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15708853%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Activation of key profibrotic mechanisms in transgenic fibroblasts expressing kinase-deficient type II Transforming growth factor-{beta} receptor (T{beta}RII{delta}k) (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15708853%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Dylan R. Edwards

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15708853%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Elisabetta Renzoni

12

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15708853%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

author name string

Christopher P Denton

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15708853%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Gisela E Lindahl

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15708853%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Korsa Khan

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15708853%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Xu Shiwen

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15708853%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Voon H Ong

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15708853%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Nicholas J Gaspar

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15708853%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Konstantinos Lazaridis

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15708853%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Andrew Leask

9

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15708853%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Mark Eastwood

10

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15708853%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Patricia Leoni

11

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15708853%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

George Bou Gharios

13

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15708853%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

David J Abraham

14

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15708853%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Carol M Black

15

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15708853%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

language of work or name

0 references

publication date

11 February 2005

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15708853%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

number of pages

13

1 reference

based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15708853%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

280

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15708853%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

16

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15708853%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

16053-16065

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15708853%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Transforming growth factor-beta and connective tissue growth factor: key cytokines in scleroderma pathogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

Insights into the molecular mechanism of chronic fibrosis: the role of connective tissue growth factor in scleroderma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

Apoptosis and myofibroblasts in the pathogenesis of systemic sclerosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

Myofibroblasts from scleroderma skin synthesize elevated levels of collagen and tissue inhibitor of metalloproteinase (TIMP-1) with two forms of TIMP-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

Smad3 as a mediator of the fibrotic response

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

Increased transcriptional activities of transforming growth factor beta receptors in scleroderma fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

Dysregulation of transforming growth factor beta signaling in scleroderma: overexpression of endoglin in cutaneous scleroderma fibroblasts.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

Autocrine overexpression of CTGF maintains fibrosis: RDA analysis of fibrosis genes in systemic sclerosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

Identification of multiple, differentially expressed messenger RNAs in dermal fibroblasts from patients with systemic sclerosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

Deficient Smad7 expression: a putative molecular defect in scleroderma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

Systemic and cell type-specific gene expression patterns in scleroderma skin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

A potential role for protease nexin 1 overexpression in the pathogenesis of scleroderma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

Systemic sclerosis (scleroderma): specific autoantigen genes are selectively overexpressed in scleroderma fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/Akt-dependent pathway and is essential for the enhanced contractile phenotype of fibrotic fibroblasts.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

Transgenic analysis of scleroderma: understanding key pathogenic events in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

Fibroblast-specific Expression of a Kinase-deficient Type II Transforming Growth Factor β (TGFβ) Receptor Leads to Paradoxical Activation of TGFβ Signaling Pathways with Fibrosis in Transgenic Mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

Expression of a dominant-negative mutant TGF-beta type II receptor in transgenic mice reveals essential roles for TGF-beta in regulation of growth and differentiation in the exocrine pancreas

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

The androgen receptor represses transforming growth factor-beta signaling through interaction with Smad3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

Matrix metalloproteinase-dependent activation of latent transforming growth factor-beta controls the conversion of osteoblasts into osteocytes by blocking osteoblast apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

Myofibroblasts and mechano-regulation of connective tissue remodelling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

Scleroderma and Smads: dysfunctional Smad family dynamics culminating in fibrosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

Mediation of transforming growth factor-beta(1)-stimulated matrix contraction by fibroblasts: a role for connective tissue growth factor in contractile scarring

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

Matrix metalloproteinase inhibitor GM 6001 attenuates keratinocyte migration, contraction and myofibroblast formation in skin wounds

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

Connective tissue growth factor gene regulation. Requirements for its induction by transforming growth factor-beta 2 in fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

Global analysis of gene expression in pulmonary fibrosis reveals distinct programs regulating lung inflammation and fibrosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

Limited agreement among three global gene expression methods highlights the requirement for non-global validation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

Combinatorial signaling pathways determine fibroblast proliferation and myofibroblast differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

Distinct endocytic pathways regulate TGF-β receptor signalling and turnover

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

An increased transforming growth factor beta receptor type I:type II ratio contributes to elevated collagen protein synthesis that is resistant to inhibition via a kinase-deficient transforming growth factor beta receptor type II in scleroderma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

The myofibroblast in wound healing and fibrocontractive diseases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

Inhibition of transforming growth factor (TGF)-beta1-induced extracellular matrix with a novel inhibitor of the TGF-beta type I receptor kinase activity: SB-431542

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413134200

21 January 2018

Identifiers

10.1074/JBC.M413134200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15708853%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15708853%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q42474271&oldid=1770299562"