(Q42477120)

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A shift towards a T cell cytokine deficiency along with an anti-inflammatory/regulatory microenvironment may enable the synthesis of anti-FVIII inhibitors in haemophilia A patients.

scientific article published on 15 September 2010

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20846164%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

A shift towards a T cell cytokine deficiency along with an anti-inflammatory/regulatory microenvironment may enable the synthesis of anti-FVIII inhibitors in haemophilia A patients (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20846164%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

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C Velloso-Rodrigues

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20846164%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

author name string

D G Chaves

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20846164%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

C A Oliveira

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20846164%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

A Teixeira-Carvalho

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20846164%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

M M Santoro

5

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Europe PubMed Central

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14 February 2020

O A Martins-Filho

6

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Europe PubMed Central

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14 February 2020

publication date

15 September 2010

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Europe PubMed Central

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14 February 2020

Clinical and Experimental Immunology

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20846164%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

162

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20846164%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

3

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Europe PubMed Central

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14 February 2020

425-437

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20846164%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Analysis of cytokine genes polymorphism as markers for inhibitor development in haemophilia A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026546

27 August 2018

Lineages of human T-cell clones, including T helper 17/T helper 1 cells, isolated at different stages of anti-factor VIII immune responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026546

27 August 2018

Strategy to assess the overall cytokine profile of circulating leukocytes and its association with distinct clinical forms of human Chagas disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026546

27 August 2018

IgG subclasses of anti-FVIII antibodies during immune tolerance induction in patients with hemophilia A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026546

27 August 2018

Factor VIII genotype and inhibitor development in patients with haemophilia A: highest risk in patients with splice site mutations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026546

27 August 2018

Reactivity profile of anti-factor VIII antibodies with designed synthetic peptides mimicking epitopes of the C2 and a1 domains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026546

27 August 2018

Immunological aspects of inhibitor development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026546

27 August 2018

Polymorphisms in the TNFA gene and the risk of inhibitor development in patients with hemophilia A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026546

27 August 2018

Inhibitor development in hemophiliacs: the roles of genetic versus environmental factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026546

27 August 2018

Tolerance to factor VIII in a transgenic mouse expressing human factor VIII cDNA carrying an Arg(593) to Cys substitution.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026546

27 August 2018

Polymorphisms in the IL10 but not in the IL1beta and IL4 genes are associated with inhibitor development in patients with hemophilia A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026546

27 August 2018

T regulatory-1 cells induce IgG4 production by B cells: role of IL-10.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026546

27 August 2018

Recognition of coagulation factor VIII by CD4+ T cells of healthy humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026546

27 August 2018

Prevention and treatment of factor VIII inhibitors in murine hemophilia A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026546

27 August 2018

Sustained high-level expression of full-length human factor VIII and restoration of clotting activity in hemophilic mice using a minimal adenovirus vector.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026546

27 August 2018

CD4+ T cell response to factor VIII in hemophilia A, acquired hemophilia, and healthy subjects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026546

27 August 2018

Functional diversity of helper T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026546

27 August 2018

Human interleukin 10 induces naive surface immunoglobulin D+ (sIgD+) B cells to secrete IgG1 and IgG3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026546

27 August 2018

Incidence of development of factor VIII and factor IX inhibitors in haemophiliacs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026546

27 August 2018

Sensitization of CD4+ T cells to coagulation factor VIII: response in congenital and acquired hemophilia patients and in healthy subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/20846164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HLA class II profile: a weak determinant of factor VIII inhibitor development in severe haemophilia A. UKHCDO Inhibitor Working Party

1 reference

https://pubmed.ncbi.nlm.nih.gov/20846164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HLA genotype of patients with severe haemophilia A due to intron 22 inversion with and without inhibitors of factor VIII

1 reference

https://pubmed.ncbi.nlm.nih.gov/20846164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mixed inflammatory/regulatory cytokine profile marked by simultaneous raise of interferon-gamma and interleukin-10 and low frequency of tumour necrosis factor-alpha(+) monocytes are hallmarks of active human visceral Leishmaniasis due to Leishmania c

1 reference

https://pubmed.ncbi.nlm.nih.gov/20846164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine production by CD4+ T cells specific for coagulation factor VIII in healthy subjects and haemophilia A patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/20846164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of Th1- and Th2-induced anti-factor VIII IgG subclasses in congenital and acquired hemophilia patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/20846164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T lymphocyte proliferative responses induced by recombinant factor VIII in hemophilia A patients with inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20846164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2249.2010.04258.X

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20846164%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

PMC publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20846164%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

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