(Q42478056)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20929960%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

title

Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20929960%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

0 references

0 references

0 references

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1 reference

18

1 reference

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15 February 2020

Jordi Alberch

24

1 reference

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15 February 2020

Onintza Sagredo

3

1 reference

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15 February 2020

María R Pazos

5

1 reference

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15 February 2020

Javier Palazuelos

7

1 reference

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15 February 2020

María Salazar

9

1 reference

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15 February 2020

Miguel Diaz-Hernandez

15

1 reference

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15 February 2020

Michael Sendtner

17

1 reference

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15 February 2020

Giovanni Marsicano

20

1 reference

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15 February 2020

Julian Romero

23

1 reference

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15 February 2020

Ismael Galve-Roperh

28

1 reference

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15 February 2020

author name string

Cristina Blázquez

1

1 reference

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15 February 2020

Anna Chiarlone

2

1 reference

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15 February 2020

Tania Aguado

4

1 reference

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15 February 2020

Eva Resel

6

1 reference

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15 February 2020

Boris Julien

8

1 reference

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15 February 2020

Christine Börner

10

1 reference

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15 February 2020

Cristina Benito

11

1 reference

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15 February 2020

Carolina Carrasco

12

1 reference

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15 February 2020

María Diez-Zaera

13

1 reference

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15 February 2020

Paola Paoletti

14

1 reference

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15 February 2020

Carolina Ruiz

16

1 reference

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15 February 2020

Justo G de Yébenes

19

1 reference

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15 February 2020

Krisztina Monory

21

1 reference

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15 February 2020

Beat Lutz

22

1 reference

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15 February 2020

Silvia Ginés

25

1 reference

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15 February 2020

Jürgen Kraus

26

1 reference

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15 February 2020

Javier Fernández-Ruiz

27

1 reference

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15 February 2020

Manuel Guzmán

29

1 reference

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15 February 2020

language of work or name

English

0 references

publication date

7 October 2010

1 reference

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15 February 2020

1 reference

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15 February 2020

volume

134

1 reference

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15 February 2020

issue

Pt 1

1 reference

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15 February 2020

page(s)

119-136

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20929960%20AND%20SRC:MED&resulttype=core&format=json

The endocannabinoid system promotes astroglial differentiation by acting on neural progenitor cells.

15 February 2020

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Mouse and rat BDNF gene structure and expression revisited

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A cell-based screen for drugs to treat Huntington's disease

21 January 2018

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Anterograde transport of brain-derived neurotrophic factor and its role in the brain.

21 January 2018

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Severe deficiency of the fatty acid amide hydrolase (FAAH) activity segregates with the Huntington's disease mutation in peripheral lymphocytes.

21 January 2018

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Cannabinoid CB1 and CB2 receptors and fatty acid amide hydrolase are specific markers of plaque cell subtypes in human multiple sclerosis.

21 January 2018

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Huntingtin modulates transcription, occupies gene promoters in vivo, and binds directly to DNA in a polyglutamine-dependent manner

21 January 2018

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21 January 2018

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Analysis of promoter regions regulating basal and interleukin-4-inducible expression of the human CB1 receptor gene in T lymphocytes

21 January 2018

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Genome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genes

21 January 2018

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Differential regulation of the expression of nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 after excitotoxicity in a rat model of Huntington's disease

21 January 2018

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Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease.

21 January 2018

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Normal huntingtin function: an alternative approach to Huntington's disease

21 January 2018

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Transcriptional signatures in Huntington's disease

21 January 2018

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Controlled clinical trial of cannabidiol in Huntington's disease

21 January 2018

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A pilot study using nabilone for symptomatic treatment in Huntington's disease

21 January 2018

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Nabilone could treat chorea and irritability in Huntington's disease

21 January 2018

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Cannabinoid receptor messenger RNA levels decrease in a subset of neurons of the lateral striatum, cortex and hippocampus of transgenic Huntington's disease mice

21 January 2018

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Cannabinoid CB2 receptor: a new target for controlling neural cell survival?

21 January 2018

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Mechanisms of control of neuron survival by the endocannabinoid system

21 January 2018

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Isolation, Structure, and Partial Synthesis of an Active Constituent of Hashish

21 January 2018

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The R6 lines of transgenic mice: a model for screening new therapies for Huntington's disease

21 January 2018

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The pattern of neurodegeneration in Huntington's disease: a comparative study of cannabinoid, dopamine, adenosine and GABA(A) receptor alterations in the human basal ganglia in Huntington's disease

21 January 2018

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Delayed onset of Huntington's disease in mice in an enriched environment correlates with delayed loss of cannabinoid CB1 receptors

21 January 2018

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Calcium signaling cascade links dopamine D1-D2 receptor heteromer to striatal BDNF production and neuronal growth

21 January 2018

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Enhanced sensitivity of striatal neurons to axonal transport defects induced by mutant huntingtin.

21 January 2018

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Coexpression of the cannabinoid receptor type 1 with dopamine and serotonin receptors in distinct neuronal subpopulations of the adult mouse forebrain.

21 January 2018

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Standardization and statistical approaches to therapeutic trials in the R6/2 mouse

21 January 2018

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Huntington's disease: from pathology and genetics to potential therapies

21 January 2018

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Gene dysregulation in Huntington's disease: REST, microRNAs and beyond

21 January 2018

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Endocannabinoid signaling as a synaptic circuit breaker in neurological disease

21 January 2018

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Involvement of brain-derived neurotrophic factor in cannabinoid receptor-dependent protection against excitotoxicity

21 January 2018

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Loss of mRNA levels, binding and activation of GTP-binding proteins for cannabinoid CB1 receptors in the basal ganglia of a transgenic model of Huntington's disease

21 January 2018

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Effects of cannabinoids in the rat model of Huntington's disease generated by an intrastriatal injection of malonate

21 January 2018

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Potential involvement of cannabinoid receptors in 3-nitropropionic acid toxicity in vivo.

21 January 2018

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The endocannabinoid pathway in Huntington's disease: a comparison with other neurodegenerative diseases

21 January 2018

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Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

21 January 2018

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CB1 cannabinoid receptors and on-demand defense against excitotoxicity

21 January 2018

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Expression of the cannabinoid receptor CB1 in distinct neuronal subpopulations in the adult mouse forebrain.

21 January 2018

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The endogenous cannabinoid system controls extinction of aversive memories

21 January 2018

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Structure, expression and regulation of the cannabinoid receptor gene (CB1) in Huntington's disease transgenic mice

21 January 2018

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Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models

21 January 2018

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Distribution and retrograde transport of trophic factors in the central nervous system: functional implications for the treatment of neurodegenerative diseases

21 January 2018

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Nabilone increases choreatic movements in Huntington's disease

21 January 2018

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Animal welfare and the refinement of neuroscience research methods--a case study of Huntington's disease models.

21 January 2018

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Microglial CB2 cannabinoid receptors are neuroprotective in Huntington's disease excitotoxicity.

21 January 2018

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An endogenous cannabinoid (2-AG) is neuroprotective after brain injury

21 January 2018

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Dopaminergic and glutamatergic signaling crosstalk in Huntington's disease neurodegeneration: the role of p25/cyclin-dependent kinase 5.

21 January 2018

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The endocannabinoid system in Huntington's disease.

21 January 2018

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Emerging strategies for exploiting cannabinoid receptor agonists as medicines

21 January 2018

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The cannabinoid receptor agonist WIN 55,212-2 attenuates the effects induced by quinolinic acid in the rat striatum.

21 January 2018

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The molecular logic of endocannabinoid signalling

21 January 2018

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Cannabinoids inhibit neurodegeneration in models of multiple sclerosis

21 January 2018

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Prevention of Alzheimer's disease pathology by cannabinoids: neuroprotection mediated by blockade of microglial activation.

21 January 2018

1 reference

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Cannabinoid CB2 receptor agonists protect the striatum against malonate toxicity: relevance for Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ278

Huntingtin regulates RE1-silencing transcription factor/neuron-restrictive silencer factor (REST/NRSF) nuclear trafficking indirectly through a complex with REST/NRSF-interacting LIM domain protein (RILP) and dynactin p150 Glued

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ278

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ278

Identification of brain-derived neurotrophic factor promoter regions mediating tissue-specific, axotomy-, and neuronal activity-induced expression in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ278

Dominant phenotypes produced by the HD mutation in STHdh(Q111) striatal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ278

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ278

Compounds blocking mutant huntingtin toxicity identified using a Huntington's disease neuronal cell model

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ278

Role of brain-derived neurotrophic factor in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ278

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ278

Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ278

21 January 2018

Identifiers

DOI

10.1093/BRAIN/AWQ278

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20929960%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference