(Q42478525)

1 November 2017

An adenoviral vector regulated by hypoxia for the treatment of ischaemic disease and cancer (English)

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1 November 2017

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K Binley

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1 November 2017

S Iqball

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1 November 2017

A Kingsman

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1 November 2017

S Kingsman

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1 November 2017

S Naylor

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1 November 2017

language of work or name

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1 October 1999

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1 November 2017

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1 November 2017

1721-1727

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https://scigraph.springernature.com/pub.10.1038/sj.gt.3301001

1 November 2017

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cites work

Transcriptional targeting of replication-defective adenovirus transgene expression to smooth muscle cells in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

In vivo therapy of hepatocellular carcinoma with a tumor-specific adenoviral vector expressing interleukin-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

The pancreatitis-associated protein I promoter allows targeting to the pancreas of a foreign gene, whose expression is up-regulated during pancreatic inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

Analysis of tissue-specific gene delivery by recombinant adenoviruses containing cardiac-specific promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

Efficient muscle-specific transgene expression after adenovirus-mediated gene transfer in mice using a 1.35 kb muscle creatine kinase promoter/enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

Functional analysis of an oxygen-regulated transcriptional enhancer lying 3' to the mouse erythropoietin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

Hypoxia-inducible nuclear factors bind to an enhancer element located 3' to the human erythropoietin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Identification of a 5' enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3' enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

Activation of hypoxia-inducible factor 1alpha: posttranscriptional regulation and conformational change by recruitment of the Arnt transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

Pathogenesis of rheumatoid arthritis: a vascular hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

A gene therapy approach to regulated delivery of erythropoietin as a function of oxygen tension

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

Regulated expression of a foreign gene targeted to the ischaemic myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

Regulation of the erythropoietin gene: evidence that the oxygen sensor is a heme protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

Recent advances in skeletal-muscle-based gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

Long-term safety and effectiveness of iron-chelation therapy with deferiprone for thalassemia major

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

Adenovirus targeted to heparan-containing receptors increases its gene delivery efficiency to multiple cell types

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

Modulation of the specificity and activity of a cellular promoter in an adenoviral vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

Progress in transcriptionally targeted and regulatable vectors for genetic therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

Muscle-based gene therapy: realistic possibilities for the future

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

Targeting gene expression to hypoxic tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

7 January 2021

Generation of recombinant adenovirus vectors with modified fibers for altering viral tropism.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

7 January 2021

Increased in vitro and in vivo gene transfer by adenovirus vectors containing chimeric fiber proteins.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

7 January 2021

Cell-specific promoter in adenovirus vector for transgenic expression of SERCA1 ATPase in cardiac myocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

7 January 2021

Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

7 January 2021

Deferoxamine followed by cyclophosphamide, etoposide, carboplatin, thiotepa, induction regimen in advanced neuroblastoma: preliminary results. Italian Neuroblastoma Cooperative Group

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

7 January 2021

Iron chelators for thalassaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

7 January 2021

Mersalyl is a novel inducer of vascular endothelial growth factor gene expression and hypoxia-inducible factor 1 activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

7 January 2021

Recent advances in inducible gene expression systems

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301001

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3301001

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Dimensions Publication ID

1 November 2017

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