(Q42498840)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162201%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

DNA methylation contributes to the regulation of sclerostin expression in human osteocytes (English)

1 reference

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18 January 2020

0 references

1

1 reference

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18 January 2020

Agustin F. Fernandez

4

1 reference

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18 January 2020

author name string

Carolina Sañudo

2

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18 January 2020

Alfonso Bolado

3

1 reference

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18 January 2020

Jana Arozamena

5

1 reference

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18 January 2020

María A Pascual-Carra

6

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18 January 2020

José C Rodriguez-Rey

7

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18 January 2020

Mario F Fraga

8

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18 January 2020

Lynda Bonewald

9

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18 January 2020

José A Riancho

10

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18 January 2020

publication date

1 April 2012

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Journal of Bone and Mineral Research

18 January 2020

published in

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18 January 2020

volume

27

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18 January 2020

issue

4

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18 January 2020

page(s)

926-937

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Sclerostin is an osteocyte-expressed negative regulator of bone formation, but not a classical BMP antagonist

18 January 2020

cites work

1 reference

Osteocyte control of bone formation via sclerostin, a novel BMP antagonist

21 January 2018

1 reference

Osteocyte-derived sclerostin inhibits bone formation: its role in bone morphogenetic protein and Wnt signaling.

21 January 2018

1 reference

Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling

21 January 2018

1 reference

Bone overgrowth-associated mutations in the LRP4 gene impair sclerostin facilitator function

21 January 2018

1 reference

Sclerostin promotes the apoptosis of human osteoblastic cells: a novel regulation of bone formation

21 January 2018

1 reference

Sclerostin is a locally acting regulator of late-osteoblast/preosteocyte differentiation and regulates mineralization through a MEPE-ASARM-dependent mechanism

21 January 2018

1 reference

Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST)

21 January 2018

1 reference

Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein

21 January 2018

1 reference

Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody

21 January 2018

1 reference

Sclerostin stimulates osteocyte support of osteoclast activity by a RANKL-dependent pathway

21 January 2018

1 reference

Control of the SOST bone enhancer by PTH using MEF2 transcription factors

21 January 2018

1 reference

SOST is a target gene for PTH in bone

21 January 2018

1 reference

Wnt inhibitors Dkk1 and Sost are downstream targets of BMP signaling through the type IA receptor (BMPRIA) in osteoblasts.

21 January 2018

1 reference

Pro-inflammatory cytokines TNF-related weak inducer of apoptosis (TWEAK) and TNFalpha induce the mitogen-activated protein kinase (MAPK)-dependent expression of sclerostin in human osteoblasts

21 January 2018

1 reference

Prostaglandin E2 signals through PTGER2 to regulate sclerostin expression

21 January 2018

1 reference

The matricellular protein periostin is required for sost inhibition and the anabolic response to mechanical loading and physical activity

21 January 2018

1 reference

Sirt1 is a regulator of bone mass and a repressor of Sost encoding for sclerostin, a bone formation inhibitor.

21 January 2018

1 reference

Human primary osteocyte differentiation in a 3D culture system.

21 January 2018

1 reference

Aberrant epigenetic landscape in cancer: how cellular identity goes awry

21 January 2018

1 reference

The role of promoter CpG methylation in the epigenetic control of stem cell related genes during differentiation

21 January 2018

1 reference

DNA methylation: the nuts and bolts of repression

21 January 2018

1 reference

Methylation status of a single CpG locus 3 bases upstream of TATA-box of receptor activator of nuclear factor-kappaB ligand (RANKL) gene promoter modulates cell- and tissue-specific RANKL expression and osteoclastogenesis.

21 January 2018

1 reference

DNA methylation and histone modification regulate silencing of OPG during tumor progression

21 January 2018

1 reference

Epigenetic modifiers influence lineage commitment of human bone marrow stromal cells: Differential effects of 5-aza-deoxycytidine and trichostatin A.

21 January 2018

1 reference

The epigenetic mechanism of mechanically induced osteogenic differentiation

21 January 2018

1 reference

21 January 2018

The amazing osteocyte

1 reference

Dynamics of the transition from osteoblast to osteocyte

21 January 2018

1 reference

Three isolation techniques for primary culture of human osteoblast-like cells: a comparison

21 January 2018

1 reference

Bisulfite conversion-specific and methylation-specific PCR: a sensitive technique for accurate evaluation of CpG methylation.

21 January 2018

1 reference

Quantitative analysis of DNA methylation after whole bisulfitome amplification of a minute amount of DNA from body fluids.

21 January 2018

1 reference

The emerging science of epigenomics

21 January 2018

1 reference

Catabolic properties of microdissected human endosteal bone lining cells

21 January 2018

1 reference

Epigenetic regulation of alkaline phosphatase in human cells of the osteoblastic lineage

21 January 2018

1 reference

Genomic patterns of DNA methylation: targets and function of an epigenetic mark

21 January 2018

1 reference

Demethylation of (Cytosine-5-C-methyl) DNA and regulation of transcription in the epigenetic pathways of cancer development.

21 January 2018

1 reference

Reactivation of transgene expression by alleviating CpG methylation of the Rous sarcoma virus promoter in transgenic quail cells

21 January 2018

1 reference

A role for DNA methylation in regulation of EphA5 receptor expression in the mouse retina

21 January 2018

1 reference

Osteocyte viability and regulation of osteoblast function in a 3D trabecular bone explant under dynamic hydrostatic pressure.

21 January 2018

1 reference

Genomic deletion of a long-range bone enhancer misregulates sclerostin in Van Buchem disease

21 January 2018

1 reference

Cbfa1/RUNX2 directs specific expression of the sclerosteosis gene (SOST)

21 January 2018

1 reference

Genomic DNA methylation: the mark and its mediators

21 January 2018

1 reference

DNA demethylation in hormone-induced transcriptional derepression

21 January 2018

1 reference

Bone morphogenetic protein-2 induces chromatin remodeling and modification at the proximal promoter of Sox9 gene

21 January 2018

1 reference