(Q42506602)

1 November 2017

Critical role of stearoyl-CoA desaturase-1 (SCD1) in the onset of diet-induced hepatic insulin resistance (English)

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1 November 2017

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Roger Gutiérrez-Juárez

1

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1 November 2017

Alessandro Pocai

2

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1 November 2017

Claudia Mulas

3

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1 November 2017

Hiraku Ono

4

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1 November 2017

Sanjay Bhanot

5

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1 November 2017

Brett P Monia

6

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1 November 2017

Luciano Rossetti

7

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1 November 2017

language of work or name

English

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publication date

1 June 2006

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Journal of Clinical Investigation

1 November 2017

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1 November 2017

116

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1 November 2017

6

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1 November 2017

1686-1695

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describes a project that uses

1 November 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1464900/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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1 reference

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Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes

28 May 2018

1 reference

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Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential in liver for the metabolism of excess acyl-CoAs

28 May 2018

1 reference

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Hypothalamic K(ATP) channels control hepatic glucose production

28 May 2018

1 reference

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Prevention of obesity in mice by antisense oligonucleotide inhibitors of stearoyl-CoA desaturase-1.

28 May 2018

1 reference

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Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease.

28 May 2018

1 reference

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Inactivation of fatty acid transport protein 1 prevents fat-induced insulin resistance in skeletal muscle

28 May 2018

1 reference

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Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes

28 May 2018

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A simple method for the isolation and purification of total lipides from animal tissues

28 May 2018

1 reference

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The role of intramuscular lipid in insulin resistance

28 May 2018

1 reference

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A central role for JNK in obesity and insulin resistance

28 May 2018

1 reference

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Relationship between stearoyl-CoA desaturase activity and plasma triglycerides in human and mouse hypertriglyceridemia

28 May 2018

1 reference

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Prevalence and Trends in Obesity Among US Adults, 1999-2000

28 May 2018

1 reference

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Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity

28 May 2018

1 reference

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Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss

28 May 2018

1 reference

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Increased insulin and leptin sensitivity in mice lacking acyl CoA:diacylglycerol acyltransferase 1.

28 May 2018

1 reference

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Overfeeding rapidly induces leptin and insulin resistance

28 May 2018

1 reference

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Central melanocortin receptors regulate insulin action

28 May 2018

1 reference

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Oleoyl-CoA is the major de novo product of stearoyl-CoA desaturase 1 gene isoform and substrate for the biosynthesis of the Harderian gland 1-alkyl-2,3-diacylglycerol

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464900

The role of lipids in the pathogenesis of muscle insulin resistance and beta cell failure in type II diabetes and obesity

28 May 2018

1 reference

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Cellular mechanisms of insulin resistance

28 May 2018

1 reference

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Leptin selectively decreases visceral adiposity and enhances insulin action.

28 May 2018

1 reference

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Mechanism by which hyperglycemia inhibits hepatic glucose production in conscious rats. Implications for the pathophysiology of fasting hyperglycemia in diabetes

28 May 2018

1 reference

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Dietary obesity in rats: Body weight and body fat accretion in seven strains of rats

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464900

Extraction of tissue long-chain acyl-CoA esters and measurement by reverse-phase high-performance liquid chromatography.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464900

Development of muscle insulin resistance after liver insulin resistance in high-fat-fed rats

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464900

Dietary obesity in nine inbred mouse strains

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464900

Predominant role of gluconeogenesis in the hepatic glycogen repletion of diabetic rats

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464900

Dietary obesity in adult rats: similarities to hypothalamic and human obesity syndromes.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464900

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464900

Inhibition of rat liver acetyl coenzyme A carboxylase by long chain acyl coenzyme A and fatty acid. Modulation by fatty acid-binding protein

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464900

Melanocortin-independent effects of leptin on hepatic glucose fluxes

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464900

Hepatic Akt activation induces marked hypoglycemia, hepatomegaly, and hypertriglyceridemia with sterol regulatory element binding protein involvement

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464900

A comparison of the prevalence of the metabolic syndrome using two proposed definitions

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464900

Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464900

Acute inhibition of glucose-6-phosphate translocator activity leads to increased de novo lipogenesis and development of hepatic steatosis without affecting VLDL production in rats

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464900

Differential effects of safflower oil versus fish oil feeding on insulin-stimulated glycogen synthesis, glycolysis, and pyruvate dehydrogenase flux in skeletal muscle: a 13C nuclear magnetic resonance study.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464900

Diabetes. Exploding type II.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464900

Intracerebroventricular leptin regulates hepatic but not peripheral glucose fluxes.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464900

Effects of high fat-feeding to rats on the interrelationship of body weight, plasma insulin, and fatty acyl-coenzyme A esters in liver and skeletal muscle

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1464900

Isocratic high-performance liquid chromatographic determination of the concentration and specific radioactivity of phosphoenolpyruvate and uridine diphosphate glucose in tissue extracts

16 August 2018

1 reference

12 December 2020

Dietary regulation of stearoyl-CoA desaturase 1 gene expression in mouse liver

1 reference

12 December 2020

Dietary obesity in the mouse: interaction of strain with diet composition

1 reference

12 December 2020

Hepatic overexpression of insulin-like growth factor-II in adulthood increases basal and insulin-stimulated glucose disposal in conscious mice

1 reference

12 December 2020

Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade

1 reference

12 December 2020

Obesity in the new millennium

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI26991

1 reference

1 November 2017

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1 November 2017

PubMed publication ID

16741579

1 reference