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Chronic exposure of HepG2 cells to excess copper results in depletion of glutathione and induction of metallothionein.
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1 reference
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Europe PubMed Central
PubMed publication ID
11869879
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869879%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
title
Chronic exposure of HepG2 cells to excess copper results in depletion of glutathione and induction of metallothionein
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11869879
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869879%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
author
Paula Aracena-Parks
series ordinal
2
1 reference
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Europe PubMed Central
PubMed publication ID
11869879
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869879%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
author name string
I Jiménez
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
11869879
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869879%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
M E Letelier
series ordinal
3
1 reference
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Europe PubMed Central
PubMed publication ID
11869879
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869879%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
P Navarro
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4
1 reference
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Europe PubMed Central
PubMed publication ID
11869879
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869879%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
H Speisky
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11869879
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869879%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
publication date
1 April 2002
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11869879
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869879%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
published in
Toxicology in Vitro
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11869879
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869879%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
volume
16
1 reference
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Europe PubMed Central
PubMed publication ID
11869879
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869879%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
issue
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11869879
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869879%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
page(s)
167-175
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11869879
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869879%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
cites work
Cytoprotective and antioxidant effects of boldine on tert-butyl hydroperoxide-induced damage to isolated hepatocytes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of dietary copper supplementation of rats on the occurrence of metallothionein-I in liver and its secretion into blood, bile and urine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of metallothionein in the hepatic metabolism of copper
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Manifestations of copper excess
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Copper(I) transfer into metallothionein mediated by glutathione
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lipid peroxidation and copper toxicity in rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Status of reduced glutathione in the human hepatoma cell line, HEP G2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evaluation of the Cd/hemoglobin affinity assay for the rapid determination of metallothionein in biological tissues
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intracellular copper transport in cultured hepatoma cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resistance of cultured hepatoma cells to copper toxicity. Purification and characterization of the hepatoma metallothionein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Metallothionein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Copper transport: an overview
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The inhibitory effects of boldine, glaucine, and probucol on TPA-induced down regulation of gap junction function. Relationships to intracellular peroxides, protein kinase C translocation, and connexin 43 phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Copper metallothionein in patients with hepatic copper overload
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of the metal binding properties of metallothionein induced by hydrogen peroxide and free radicals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of copper ions on the free radical-scavenging properties of reduced gluthathione: implications of a complex formation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Outputs of hepatic copper and cadmium stimulated by tetrathiomolybdate (TTM) injection in Long-Evans Cinnamon (LEC) rats pretreated with cadmium, and in Fischer rats pretreated with copper and cadmium.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Copper transport
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thiol-disulfide effects on hepatic glutathione transport. Studies in cultured rat hepatocytes and perfused livers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Liver copper storage and transport during development: implications for cytotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Metallothionein concentration in the liver of patients with Wilson's disease, primary biliary cirrhosis, and liver metastasis of colorectal cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of glutathione depletion and induction of metallothioneins on the cytotoxicity of an organic hydroperoxide in cultured mammalian cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of selective copper removal by tetrathiomolybdate from metallothionein in LEC rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A delicate balance: homeostatic control of copper uptake and distribution
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evaluation of 2',7'-dichlorofluorescin and dihydrorhodamine 123 as fluorescent probes for intracellular H2O2 in cultured endothelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Copper-metallothionein induction in the liver of LEC rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Unusual generation of hydroxyl radicals in hepatic copper-metallothionein of LEC (Long-Evans cinnamon) rats in the presence of hydrogen peroxide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
12 Quantification of metallothionein by silver saturation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hepatocellular copper toxicity and its attenuation by zinc
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Copper resistant human hepatoblastoma mutant cell lines without metallothionein induction overexpress ATP7B.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxidant injury to hepatic mitochondrial lipids in rats with dietary copper overload. Modification by vitamin E deficiency
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of cytosolic copper, metallothionein and glutathione in copper toxicity in rat hepatoma tissue culture cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Copper-metallothionein from the toxic milk mutant mouse enhances lipid peroxidation initiated by an organic hydroperoxide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Low content of hepatic reduced glutathione in patients with Wilson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Copper metabolism leading to and following acute hepatitis in LEC rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective removal of copper bound to metallothionein in the liver of LEC rats by tetrathiomolybdate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms for removal of copper from metallothionein by tetrathiomolybdate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0887-2333%2801%2900117-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0887-2333(01)00117-5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11869879
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869879%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
PubMed publication ID
11869879
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11869879
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869879%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
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