(Q42518946)

English

Reactive nitrogen species induced by hyperglycemia suppresses Akt signaling and triggers apoptosis by upregulating phosphatase PTEN (phosphatase and tensin homologue deleted on chromosome 10) in an LKB1-dependent manner

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

retracted paper

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Retraction Watch

29 December 2023

https://doi.org/10.1161/CIR.0000000000000919

http://retractionwatch.com/2020/01/13/georgia-state-researcher-up-to-nine-retractions-disagrees-with-the-journal/

Reactive nitrogen species induced by hyperglycemia suppresses Akt signaling and triggers apoptosis by upregulating phosphatase PTEN (phosphatase and tensin homologue deleted on chromosome 10) in an LKB1-dependent manner (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

1 reference

based on heuristic

inferred from title

apoptotic process

1 reference

based on heuristic

inferred from title

1

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

author name string

Yong Wu

2

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

Jian Xu

3

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

Zhonglin Xie

4

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

Yunzhou Dong

5

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

Miao Zhang

6

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

Ming-Hui Zou

7

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

language of work or name

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publication date

17 September 2007

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

116

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

14

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

1585-1595

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity [corrected]

1 reference

30 December 2023

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Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation

1 reference

30 December 2023

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PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

1 reference

30 December 2023

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Myocardial cell death in human diabetes

1 reference

30 December 2023

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Mitochondrial H2O2 regulates the angiogenic phenotype via PTEN oxidation.

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

Peroxynitrite and vascular endothelial dysfunction in diabetes mellitus.

1 reference

30 December 2023

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Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group

1 reference

30 December 2023

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High glucose via peroxynitrite causes tyrosine nitration and inactivation of prostacyclin synthase that is associated with thromboxane/prostaglandin H(2) receptor-mediated apoptosis and adhesion molecule expression in cultured human aortic endotheli

1 reference

30 December 2023

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New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

1 reference

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Beta-cell apoptosis is responsible for the development of IDDM in the multiple low-dose streptozotocin model

1 reference

30 December 2023

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Tempol reduces oxidative stress, improves insulin sensitivity, decreases renal dopamine D1 receptor hyperphosphorylation, and restores D1 receptor-G-protein coupling and function in obese Zucker rats

1 reference

30 December 2023

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Nitric oxide, oxidants, and protein tyrosine nitration

1 reference

30 December 2023

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Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association

1 reference

30 December 2023

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Membrane-binding and activation mechanism of PTEN.

1 reference

30 December 2023

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Hyperglycemia-induced apoptosis in human umbilical vein endothelial cells: inhibition by the AMP-activated protein kinase activation

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

Activation of protein kinase C zeta by peroxynitrite regulates LKB1-dependent AMP-activated protein kinase in cultured endothelial cells.

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

Redox regulation of PI 3-kinase signalling via inactivation of PTEN

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

Phosphorylation of the PTEN tail regulates protein stability and function

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

The tumor suppressor PTEN negatively regulates insulin signaling in 3T3-L1 adipocytes

1 reference

30 December 2023

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Intensive diabetes therapy and carotid intima-media thickness in type 1 diabetes mellitus

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

LKB1 interacts with and phosphorylates PTEN: a functional link between two proteins involved in cancer predisposing syndromes

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

1 reference

30 December 2023

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Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action

1 reference

30 December 2023

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3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

Nitric oxide release accounts for insulin's vascular effects in humans

1 reference

30 December 2023

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Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

Activation of 5'-AMP-activated kinase is mediated through c-Src and phosphoinositide 3-kinase activity during hypoxia-reoxygenation of bovine aortic endothelial cells. Role of peroxynitrite.

2 references

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

30 December 2023

https://opencitations.net/index/api/v1/citations/10.1074/JBC.M300215200

Enhanced peroxynitrite formation is associated with vascular aging

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

Insulin hypersensitivity and resistance to streptozotocin-induced diabetes in mice lacking PTEN in adipose tissue

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

Modulation by peroxynitrite of Akt- and AMP-activated kinase-dependent Ser1179 phosphorylation of endothelial nitric oxide synthase.

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

Tumor suppressor PTEN acts through dynamic interaction with the plasma membrane

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

Free fatty acids inhibit insulin signaling-stimulated endothelial nitric oxide synthase activation through upregulating PTEN or inhibiting Akt kinase

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

Specific inhibition of PTEN expression reverses hyperglycemia in diabetic mice

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

Muscle-specific Pten deletion protects against insulin resistance and diabetes

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

Peroxynitrite-mediated oxidation of dihydrorhodamine 123

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

Up-regulation of PTEN (phosphatase and tensin homolog deleted on chromosome ten) mediates p38 MAPK stress signal-induced inhibition of insulin signaling. A cross-talk between stress signaling and insulin signaling in resistin-treated human endotheli

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

Reversible inactivation of the tumor suppressor PTEN by H2O2

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

Skeletal muscle-selective knockout of LKB1 increases insulin sensitivity, improves glucose homeostasis, and decreases TRB3

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

Peroxynitrite causes endoplasmic reticulum stress and apoptosis in human vascular endothelium: implications in atherogenesis

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

Free radicals, mitochondria, and oxidized lipids: the emerging role in signal transduction in vascular cells

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

Superoxide reacts with nitric oxide to nitrate tyrosine at physiological pH via peroxynitrite.

1 reference

30 December 2023

https://opencitations.net/index/api/v1/references/10.1161/CIRCULATIONAHA.107.716498

Identifiers

10.1161/CIRCULATIONAHA.107.716498

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 November 2017

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