(Q42526981)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12384935%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

title

Halofuginone inhibition of COL1A2 promoter activity via a c-Jun-dependent mechanism (English)

1 reference

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14 December 2019

1

1 reference

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14 December 2019

author name string

Takao Kodera

2

1 reference

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14 December 2019

Harry Spiera

3

1 reference

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14 December 2019

Alexandru C Stan

4

1 reference

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14 December 2019

Mark Pines

5

1 reference

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14 December 2019

Constantin A Bona

6

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14 December 2019

publication date

1 October 2002

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14 December 2019

published in

Arthritis and Rheumatism

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14 December 2019

volume

46

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14 December 2019

issue

10

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14 December 2019

page(s)

2748-2761

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Wound healing--aiming for perfect skin regeneration

14 December 2019

cites work

1 reference

Clinical manifestations of systemic sclerosis

21 January 2018

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Lung interleukin-4 gene expression in a murine model of bleomycin-induced pulmonary fibrosis

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Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in nonobese diabetic (NOD) mice

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Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1).

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Fibrillin, a new 350-kD glycoprotein, is a component of extracellular microfibrils

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Fibrillin-1 protein in tight skin mice and scleroderma

21 January 2018

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Halofuginone: an inhibitor of collagen type I synthesis

21 January 2018

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Halofuginone to prevent and treat thioacetamide-induced liver fibrosis in rats

21 January 2018

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Halofuginone, an inhibitor of type-I collagen synthesis and skin sclerosis, blocks transforming-growth-factor-beta-mediated Smad3 activation in fibroblasts.

21 January 2018

1 reference

Reduction in dermal fibrosis in the tight-skin (Tsk) mouse after local application of halofuginone

21 January 2018

1 reference

Synergistic cooperation between Sp1 and Smad3/Smad4 mediates transforming growth factor beta1 stimulation of alpha 2(I)-collagen (COL1A2) transcription

21 January 2018

1 reference

Sp1 is required for the early response of alpha2(I) collagen to transforming growth factor-beta1.

21 January 2018

1 reference

Increased phosphorylation of transcription factor Sp1 in scleroderma fibroblasts: association with increased expression of the type I collagen gene

21 January 2018

1 reference

An AP-1 binding sequence is essential for regulation of the human alpha2(I) collagen (COL1A2) promoter activity by transforming growth factor-beta.

21 January 2018

1 reference

An activator protein-1 (AP-1) response element on pro alpha1(l) collagen gene is necessary for thyroid hormone-induced inhibition of promoter activity in cardiac fibroblasts

21 January 2018

1 reference

Increased alpha 1(I) procollagen gene expression in tight skin (TSK) mice myocardial fibroblasts is due to a reduced interaction of a negative regulatory sequence with AP-1 transcription factor

21 January 2018

1 reference

Retinoic acid inhibits induction of c-Jun protein by ultraviolet radiation that occurs subsequent to activation of mitogen-activated protein kinase pathways in human skin in vivo

21 January 2018

1 reference

c-Jun-dependent inhibition of cutaneous procollagen transcription following ultraviolet irradiation is reversed by all-trans retinoic acid

21 January 2018

1 reference

Molecular mechanisms of TGF-(beta) antagonism by interferon (gamma) and cyclosporine A in lung fibroblasts

21 January 2018

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Estradiol suppresses type I collagen synthesis in mesangial cells via activation of activator protein-1.

21 January 2018

1 reference

The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins

21 January 2018

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Variations in Jun and Fos protein expression and AP-1 activity in cycling, resting and stimulated fibroblasts

21 January 2018

1 reference

Existence of different Fos/Jun complexes during the G0-to-G1 transition and during exponential growth in mouse fibroblasts: differential role of Fos proteins

21 January 2018

1 reference

Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity

21 January 2018

1 reference

Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription

21 January 2018

1 reference

Close encounters of many kinds: Fos-Jun interactions that mediate transcription regulatory specificity.

21 January 2018

1 reference

A transcriptionally active DNA-binding site for human p53 protein complexes

21 January 2018

1 reference

Interaction of Ap1, Ap2, and Sp1 with the regulatory regions of the human pro-alpha1(I) collagen gene

21 January 2018

1 reference

CTGF and SMADs, maintenance of scleroderma phenotype is independent of SMAD signaling

21 January 2018

1 reference

Infusion of iloprost, a prostacyclin analogue, for treatment of Raynaud's phenomenon in systemic sclerosis

21 January 2018

1 reference

Iloprost suppresses connective tissue growth factor production in fibroblasts and in the skin of scleroderma patients

21 January 2018

1 reference

Relaxin favors the development of activated human T cells into Th1-like effectors

21 January 2018

1 reference

SB 239063, a p38 MAPK inhibitor, reduces neutrophilia, inflammatory cytokines, MMP-9, and fibrosis in lung

21 January 2018

1 reference

Effect of pentoxifylline on the degradation of procollagen type I produced by human hepatic stellate cells in response to transforming growth factor-beta 1.

21 January 2018

1 reference

Pentoxifylline inhibits human peritoneal mesothelial cell growth and collagen synthesis: effects on TGF-beta.

21 January 2018

1 reference

Halofuginone: a potent inhibitor of critical steps in angiogenesis progression

21 January 2018

1 reference