(Q42538033)

1 November 2017

Rapamycin induces autophagic flux in neurons (English)

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1 November 2017

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David C Rubinsztein

1

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1 November 2017

Ralph A Nixon

series ordinal

2

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1 November 2017

language of work or name

English

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publication date

29 November 2010

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Proceedings of the National Academy of Sciences of the United States of America

1 November 2017

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1 November 2017

107

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1 November 2017

49

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1 November 2017

E181; author reply E182

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A small-molecule scaffold induces autophagy in primary neurons and protects against toxicity in a Huntington disease model.

1 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000262

The mTOR kinase inhibitor Everolimus decreases S6 kinase phosphorylation but fails to reduce mutant huntingtin levels in brain and is not neuroprotective in the R6/2 mouse model of Huntington's disease

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000262

Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000262

Selective molecular alterations in the autophagy pathway in patients with Lewy body disease and in models of alpha-synucleinopathy

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000262

Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3000262

28 May 2018

Identifiers

DOI

10.1073/PNAS.1014633107

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1 November 2017

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1 reference

1 November 2017

PubMed publication ID

21115811

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