(Q42539670)

2 November 2017

title

Phase I trial of edatrexate plus carboplatin in advanced solid tumors: amelioration of dose-limiting mucositis by ice chip cryotherapy (English)

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2 November 2017

main subject

phase I clinical trial

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Edelman MJ

1

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2 November 2017

Gandara DR

2

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2 November 2017

Perez EA

3

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2 November 2017

Lau D

4

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2 November 2017

Lauder I

5

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2 November 2017

Turrell C

6

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2 November 2017

Uhrich M

7

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2 November 2017

Meyers F

8

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2 November 2017

publication date

1 January 1998

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Investigational New Drugs

2 November 2017

published in

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2 November 2017

volume

16

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2 November 2017

issue

1

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2 November 2017

page(s)

69-75

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https://scigraph.springernature.com/pub.10.1023/a:1006026928733

2 November 2017

exact match

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cites work

Edatrexate, an antifolate with antitumor activity: a review

1 reference

12 December 2020

Markedly improved efficacy of edatrexate compared to methotrexate in a high-dose regimen with leucovorin rescue against metastatic murine solid tumors.

1 reference

12 December 2020

Edatrexate improves the antitumor effects of cyclophosphamide and cisplatin against non-small cell lung cancer

1 reference

12 December 2020

Schedule-dependent synergism of edatrexate and cisplatin in combination in the A549 lung-cancer cell line as assessed by median-effect analysis

1 reference

12 December 2020

New folate analogs of the 10-deaza-aminopterin series: markedly increased antitumor activity of the 10-ethyl analog compared to the parent compound and methotrexate against some human tumor xenografts in nude mice.

1 reference

12 December 2020

Phase II study of 10-ethyl-10-deaza-aminopterin (10-EdAM; CGP 30 694) for stage IIIB or IV non-small cell lung cancer

1 reference

12 December 2020

Randomized phase III trial of edatrexate versus methotrexate in patients with metastatic and/or recurrent squamous cell carcinoma of the head and neck: a European Organization for Research and Treatment of Cancer Head and Neck Cancer Cooperative Gro

1 reference

12 December 2020

Pharmacokinetics of 10-ethyl-10-deaza-aminopterin, edatrexate, given weekly for non-small-cell lung cancer

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12 December 2020

Phase II study of weekly edatrexate as first-line chemotherapy for metastatic breast cancer: a National Cancer Institute of Canada Clinical Trials Group study

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12 December 2020

Inhibition of fluorouracil-induced stomatitis by oral cryotherapy

1 reference

12 December 2020

Phase I trial and clinical pharmacological evaluation of 10-ethyl-10-deazaaminopterin in adult patients with advanced cancer

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12 December 2020

Quantitation of the synergistic interaction of edatrexate and cisplatin in vitro

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12 December 2020

Modulation of intrinsic in vitro resistance to carboplatin by edatrexate in the A549 human nonsmall cell lung cancer cell line.

1 reference

12 December 2020

Leucovorin rescue of human cancer and bone marrow cells following edatrexate or methotrexate

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12 December 2020

Alleviation by leucovorin of the dose-limiting toxicity of edatrexate: potential for improved therapeutic efficacy

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12 December 2020

Carboplatin dosage: prospective evaluation of a simple formula based on renal function

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12 December 2020

New folate analogs of the 10-deaza-aminopterin series. Further evidence for markedly increased antitumor efficacy compared with methotrexate in ascitic and solid murine tumor models

1 reference

12 December 2020

New folate analogs of the 10-deaza-aminopterin series. Basis for structural design and biochemical and pharmacologic properties

1 reference

12 December 2020

Phase II study of 10-ethyl-10-deaza-aminopterin in patients with stage III and IV non-small-cell lung cancer

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1006026928733

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Dimensions Publication ID

2 November 2017

1048612225

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