(Q42539779)

English

High levels of 5-hydroxymethylcytosine (5hmC) is an adverse predictor of biochemical recurrence after prostatectomy in ERG-negative prostate cancer

scientific article published on 15 October 2015

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

High levels of 5-hydroxymethylcytosine (5hmC) is an adverse predictor of biochemical recurrence after prostatectomy in ERG-negative prostate cancer (English)

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

Karina Dalsgaard Sørensen

8

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

author name string

Siri H Strand

1

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

Soren Hoyer

2

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

Anne-Sofie Lynnerup

3

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

Christa Haldrup

4

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

Tine Maj Storebjerg

5

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

Michael Borre

6

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

Torben F Orntoft

7

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

publication date

15 October 2015

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

Clinical Epigenetics

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

7

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

111

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

Charting oxidized methylcytosines at base resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

Characterization of 1577 primary prostate cancers reveals novel biological and clinicopathologic insights into molecular subtypes

1 reference

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28 May 2018

Zodiac: A Comprehensive Depiction of Genetic Interactions in Cancer by Integrating TCGA Data

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28 May 2018

The oncogene ERG: a key factor in prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

Genomic Predictors of Outcome in Prostate Cancer

1 reference

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28 May 2018

5-hydroxymethylcytosine marks promoters in colon that resist DNA hypermethylation in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

5-Hydroxymethylcytosine: An epigenetic mark frequently deregulated in cancer

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28 May 2018

TET1 regulates hypoxia-induced epithelial-mesenchymal transition by acting as a co-activator

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28 May 2018

TMPRSS2-ERG gene fusion in prostate cancer.

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28 May 2018

Prognostic DNA methylation markers for prostate cancer.

1 reference

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28 May 2018

TCGA-assembler: open-source software for retrieving and processing TCGA data

1 reference

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28 May 2018

TET1-mediated hydroxymethylation facilitates hypoxic gene induction in neuroblastoma

1 reference

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28 May 2018

Epigenetic modification of Nrf2 in 5-fluorouracil-resistant colon cancer cells: involvement of TET-dependent DNA demethylation

1 reference

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28 May 2018

Hypermethylation of the GABRE~miR-452~miR-224 promoter in prostate cancer predicts biochemical recurrence after radical prostatectomy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

Global transcriptome analysis of formalin-fixed prostate cancer specimens identifies biomarkers of disease recurrence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

Analysis of TET expression/activity and 5mC oxidation during normal and malignant germ cell development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

5-hydroxymethylcytosine: a new insight into epigenetics in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

A screen for hydroxymethylcytosine and formylcytosine binding proteins suggests functions in transcription and chromatin regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

Tight correlation of 5-hydroxymethylcytosine and Polycomb marks in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

A 36-gene signature predicts clinical progression in a subgroup of ERG-positive prostate cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

Prognostic significance of aberrantly silenced ANPEP expression in prostate cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

Epigenetic biomarkers in prostate cancer: Current and future uses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

Loss of 5-hydroxymethylcytosine is accompanied with malignant cellular transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

ERG protein expression and genomic rearrangement status in primary and metastatic prostate cancer--a comparative study of two monoclonal antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

TMPRSS2-ERG -specific transcriptional modulation is associated with prostate cancer biomarkers and TGF-β signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

5-Hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

Association of PITX2 mRNA down-regulation in prostate cancer with promoter hypermethylation and poor prognosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

Distribution of 5-hydroxymethylcytosine in different human tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

Antibody-based detection of ERG rearrangement-positive prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

The role of SPINK1 in ETS rearrangement-negative prostate cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

The expanding role of epigenetics in the development, diagnosis and treatment of prostate cancer and benign prostatic hyperplasia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

The 2005 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

20-year outcomes following conservative management of clinically localized prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

28 May 2018

Distinct global DNA methylation status in B-cell lymphomas: immunohistochemical study of 5-methylcytosine and 5-hydroxymethylcytosine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

16 August 2018

DNA methylation signatures for prediction of biochemical recurrence after radical prostatectomy of clinically localized prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

16 August 2018

Decreased 5-hydroxymethylcytosine levels are associated with TET2 mutation and unfavorable overall survival in myelodysplastic syndromes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

16 August 2018

Low values of 5-hydroxymethylcytosine (5hmC), the "sixth base," are associated with anaplasia in human brain tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

16 August 2018

The Ability of Biomarkers to Predict Systemic Progression in Men with High-Risk Prostate Cancer Treated Surgically Is Dependent on ERG Status

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

16 August 2018

Mutational analysis of IDH1 codon 132 in glioblastomas and other common cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

16 August 2018

Intrinsic markers of tumour hypoxia and angiogenesis in localised prostate cancer and outcome of radical treatment: a retrospective analysis of two randomised radiotherapy trials and one surgical cohort study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

16 August 2018

Estimating lead time and overdiagnosis associated with PSA screening from prostate cancer incidence trends

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608326

16 August 2018

Characterization of acute myeloid leukemia based on levels of global hydroxymethylation

1 reference

https://api.crossref.org/works/10.1186%2FS13148-015-0146-5

21 January 2018

Correlation of ERG Expression and DNA Methylation Biomarkers with Adverse Clinicopathologic Features of Prostate Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/26478752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased 5-hydroxymethylcytosine (5-hmC) is an independent poor prognostic factor in gastric cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/26478752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered DNA Methylation Landscapes of Polycomb-Repressed Loci Are Associated with Prostate Cancer Progression and ERG Oncogene Expression in Prostate Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/26478752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/S13148-015-0146-5

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

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0 references

release_ffvs2krnsrgc5e67rwf7q5nutu

1 reference

https://api.fatcat.wiki/v0/release/ffvs2krnsrgc5e67rwf7q5nutu

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

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