(Q42541290)

English

Withdrawal from 3alpha-OH-5alpha-pregnan-20-One using a pseudopregnancy model alters the kinetics of hippocampal GABAA-gated current and increases the GABAA receptor alpha4 subunit in association with increased anxiety.

scientific article published on July 1998

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12 November 2019

Withdrawal from 3alpha-OH-5alpha-pregnan-20-One using a pseudopregnancy model alters the kinetics of hippocampal GABAA-gated current and increases the GABAA receptor alpha4 subunit in association with increased anxiety (English)

1 reference

Europe PubMed Central

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12 November 2019

author name string

S S Smith

1

1 reference

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12 November 2019

Q H Gong

2

1 reference

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12 November 2019

X Li

3

1 reference

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12 November 2019

M H Moran

4

1 reference

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12 November 2019

D Bitran

5

1 reference

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12 November 2019

C A Frye

6

1 reference

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12 November 2019

F C Hsu

7

1 reference

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12 November 2019

language of work or name

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publication date

1 July 1998

1 reference

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12 November 2019

Journal of Neuroscience

1 reference

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12 November 2019

18

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12 November 2019

5275-5284

1 reference

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12 November 2019

14

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12 November 2019

Chronic intermittent ethanol treatment in rats increases GABA(A) receptor alpha4-subunit expression: possible relevance to alcohol dependence

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug discrimination analysis of endogenous neuroactive steroids in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[The neurochemical profile of the dorsal hippocampus and the antiaversive effects of anxiolytics in different models of anxiety in rats]

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinctive patterns of GABAA receptor subunit mRNAs in 13 cell lines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning, pharmacological characteristics and expression pattern of the rat GABAA receptor alpha 4 subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyclonal antibodies directed against an epitope specific for the alpha 4-subunit of GABAA receptors identify a 67-kDa protein in rat brain membranes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamics of progesterone metabolism in the pseudopregnant rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anxiolytic effects of 3α-hydroxy-5α[β]-pregnan-20-one: endogenous metabolites of progesterone that are active at the GABAA receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neurosteroid 3 alpha, 5 apha-THP has antiseizure and possible neuroprotective effects in an animal model of epilepsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional characterization of human gamma-aminobutyric acidA receptors containing the alpha 4 subunit.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radioimmunoassay of 3 alpha-hydroxy-5 alpha-pregnan-20-one in rat and human plasma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The kindling model of alcohol dependence: similar persistent reduction in seizure threshold to pentylenetetrazol in animals receiving chronic ethanol or chronic pentylenetetrazol.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GABA(A) receptor alpha4 subunit suppression prevents withdrawal properties of an endogenous steroid.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Messenger RNA phenotyping for semi-quantitative comparison of glucocorticoid receptor transcript levels in the developing embryonic mouse palate

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation factors control neurotransmitter and neuromodulator actions at the gamma-aminobutyric acid type A receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stress-induced elevations of gamma-aminobutyric acid type A receptor-active steroids in the rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Female sex steroid hormones: from receptors to networks to performance--actions on the sensorimotor system

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation and deactivation rates of recombinant GABA(A) receptor channels are dependent on alpha-subunit isoform

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurosteroid regulation of GABAA receptor single-channel kinetic properties of mouse spinal cord neurons in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Silent GABAA synapses during flurazepam withdrawal are region-specific in the hippocampal formation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid development of tolerance to the sedative effects of lorazepam and triazolam in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic neurosteroid treatment produces functional heterologous uncoupling at the gamma-aminobutyric acid type A/benzodiazepine receptor complex in mammalian cortical neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced benzodiazepine sensitivity in patients with premenstrual syndrome: a pilot study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological modulation of the diazepam-insensitive recombinant gamma-aminobutyric acidA receptors alpha 4 beta 2 gamma 2 and alpha 6 beta 2 gamma 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The estrous cycle and the olivo-cerebellar circuit. I. Contrast enhancement of sensorimotor-correlated cerebellar discharge.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Locally applied progesterone metabolites alter neuronal responsiveness in the cerebellum.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction of GABA-mediated inhibitory postsynaptic potentials in hippocampal CA1 pyramidal neurons following oral flurazepam administration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurosteroids: 3 alpha-hydroxy-5 alpha-pregnan-20-one and its precursors in the brain, plasma, and steroidogenic glands of male and female rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunoaffinity purification of gamma-aminobutyric acidA (GABAA) receptors containing gamma 1-subunits. Evidence for the presence of a single type of gamma-subunit in GABAA receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The influence of estrus cycle on neurosteroid potency at the gamma-aminobutyric acidA receptor complex.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neurosteroid, 3 alpha-hydroxy-5 alpha-pregnan-20-one, protects against bicuculline-induced seizures during ethanol withdrawal in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Precipitation of benzodiazepine withdrawal following sudden discontinuation of midazolam.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bidirectional alterations of GABA(A) receptor subunit peptide levels in rat cortex during chronic ethanol consumption and withdrawal.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progesterone metabolite allopregnanolone in women with premenstrual syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gamma-aminobutyric acidA receptor regulation: chronic treatment with pregnanolone uncouples allosteric interactions between steroid and benzodiazepine recognition sites.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anticonvulsant profile of the progesterone metabolite 5 alpha-pregnan-3 alpha-ol-20-one

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

gamma-Aminobutyric acidA receptor regulation in culture: altered allosteric interactions following prolonged exposure to benzodiazepines, barbiturates, and methylxanthines

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic treatment with diazepam or abecarnil differently affects the expression of GABAA receptor subunit mRNAs in the rat cortex.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Withdrawal from the endogenous steroid progesterone results in GABAA currents insensitive to benzodiazepine modulation in rat CA1 hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ovarian endocrine status modulates the anxiolytic potency of diazepam and the efficacy of !g-aminobutyric acid-benzodiazepine receptor-mediated chloride ion transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Finasteride blocks the reduction in ictal activity produced by exogenous estrous cyclicity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influences of gender, gonadectomy, and estrous cycle on GABA/BZ receptors and benzodiazepine responses in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Delta subunit inhibits neurosteroid modulation of GABAA receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Benzodiazepine agonist and inverse agonist actions on GABAA receptor-operated chloride channels. II. Chronic effects of ethanol.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamics of the hippocampal ensemble code for space.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of the dorsal hippocampus in mediation of the antianxiety action of tandospirone, a 5-hydroxytryptamine1A agonistic anxiolytic

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progesterone withdrawal decreases latency to and increases duration of electrified prod burial: a possible rat model of PMS anxiety.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The anxiolytic-like effects of the neurosteroid allopregnanolone: interactions with GABA(A) receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progesterone and the premenstrual syndrome: a double blind crossover trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tetrahydro-beta-carboline micro-injected into the hippocampus induces an anxiety-like state in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ovarian steroids modify the behavioral and neurochemical responses of the central benzodiazepine receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The actions of diazepam and serotonergic anxiolytics vary according to the gender and the estrous cycle phase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Periodic benzodiazepine antagonist administration prevents benzodiazepine withdrawal symptoms in primates.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progesterone enhances inhibitory responses of cerebellar Purkinje cells mediated by the GABAA receptor subtype

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of putative anxiogenic compounds (FG 7142, CGS 8216 and Ro 15-1788) on the rat corticosterone response.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The history of benzodiazepine dependence: a review of animal studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anxiolytic effect of progesterone is associated with increases in cortical allopregnanolone and GABAA receptor function.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progesterone alters GABA and glutamate responsiveness: a possible mechanism for its anxiolytic action

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Steroidogenic effects of lipoproteins and 25-hydroxycholesterol on luteal and ovarian cells: a comparison of two pseudopregnant rat models

1 reference

https://pubmed.ncbi.nlm.nih.gov/9651210

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.18-14-05275.1998

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9651210%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9651210%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9651210%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

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