(Q42544516)

English

Physiological antagonism between ventricular beta 1-adrenoceptors and alpha 1-adrenoceptors but no evidence for beta 2- and beta 3-adrenoceptor function in murine heart

scientific article published on May 2002

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

Physiological antagonism between ventricular beta 1-adrenoceptors and alpha 1-adrenoceptors but no evidence for beta 2- and beta 3-adrenoceptor function in murine heart (English)

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

author name string

Jürgen F Heubach

1

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

Thomas Rau

2

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

Thomas Eschenhagen

3

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

Ursula Ravens

4

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

Alberto J Kaumann

5

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

language of work or name

0 references

publication date

1 May 2002

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

British Journal of Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

136

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

2

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

217-229

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

Murine ventricular L-type Ca(2+) current is enhanced by zinterol via beta(1)-adrenoceptors, and is reduced in TG4 mice overexpressing the human beta(2)-adrenoceptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573340

28 May 2018

Abolition of (-)-CGP 12177-evoked cardiostimulation in double beta1/beta2-adrenoceptor knockout mice. Obligatory role of beta1-adrenoceptors for putative beta4-adrenoceptor pharmacology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573340

28 May 2018

alpha-Adrenoceptor stimulation-mediated negative inotropism and enhanced Na(+)/Ca(2+) exchange in mouse ventricle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573340

28 May 2018

L-type calcium current and contractility in ventricular myocytes from mice overexpressing the cardiac beta 2-adrenoceptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573340

28 May 2018

The negative inotropic effect of beta3-adrenoceptor stimulation is mediated by activation of a nitric oxide synthase pathway in human ventricle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573340

28 May 2018

International Union of Pharmacology. XVII. Classification of muscarinic acetylcholine receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573340

28 May 2018

Proposal for the interaction of non-conventional partial agonists and catecholamines with the 'putative beta 4-adrenoceptor' in mammalian heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573340

28 May 2018

alpha 1-adrenoceptor-mediated negative inotropy of adrenaline in rat myocardium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573340

28 May 2018

Functional beta3-adrenoceptor in the human heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573340

28 May 2018

Targeted disruption of the mouse beta1-adrenergic receptor gene: developmental and cardiovascular effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573340

28 May 2018

Beta 3 and atypical beta-adrenoceptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573340

28 May 2018

Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the beta 2-adrenoceptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573340

28 May 2018

Sustained negative inotropism mediated by alpha-adrenoceptors in adult mouse myocardia: developmental conversion from positive response in the neonate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573340

28 May 2018

Classification of alpha 1-adrenoceptor subtypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573340

28 May 2018

Inhibition of sympathomimetic effects on the cardiovascular system by 4-(2-isopropylamino-1-hydroxyethyl)methanesulfonanilide hydrochloride (MJ 1999)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573340

28 May 2018

Pertussis toxin-treated dog: a whole animal model of impaired inhibitory regulation of adenylate cyclase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573340

28 May 2018

CGP 20712 A: a useful tool for quantitating beta 1- and beta 2-adrenoceptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573340

28 May 2018

Contribution of beta 1- and beta 2-adrenoceptors of human atrium and ventricle to the effects of noradrenaline and adrenaline as assessed with (-)-atenolol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573340

28 May 2018

Increase of the 40,000-mol wt pertussis toxin substrate (G protein) in the failing human heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573340

28 May 2018

Increase of Gi alpha in human hearts with dilated but not ischemic cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573340

28 May 2018

Beta 1- and beta 2-adrenoceptors in sheep cardiac ventricular muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573340

28 May 2018

The effect of pertussis toxin on beta-adrenoceptor responses in isolated cardiac myocytes from noradrenaline-treated guinea-pigs and patients with cardiac failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573340

28 May 2018

Comparison of the affinity of beta-blockers for two states of the beta 1-adrenoceptor in ferret ventricular myocardium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573340

16 August 2018

Beta-adrenergic receptor subtype-specific signaling in cardiac myocytes from beta(1) and beta(2) adrenoceptor knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573340

16 August 2018

Beta(2)-adrenergic and several other G protein-coupled receptors in human atrial membranes activate both G(s) and G(i).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573340

16 August 2018

Pertussis toxin suppresses carbachol-evoked cardiodepression but does not modify cardiostimulation mediated through beta1- and putative beta4-adrenoceptors in mouse left atria: no evidence for beta2- and beta3-adrenoreceptor function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573340

16 August 2018

Enhanced myocardial function in transgenic mice overexpressing the beta 2-adrenergic receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573340

16 August 2018

Beta 2-adrenergic receptor actions in neonatal and adult rat ventricular myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573340

16 August 2018

The Pharmacology of a β2-Selective Adrenoceptor Antagonist (ICI 118,551)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573340

16 August 2018

An analysis of cholinergic involvement in postvagal tachycardia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12010770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Demonstration of an alpha adrenoceptor-mediated inotropic effect of norepinephrine in human atria

1 reference

https://pubmed.ncbi.nlm.nih.gov/12010770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The affinity of (-)-propranolol for beta 1- and beta 2-adrenoceptors of human heart. Differential antagonism of the positive inotropic effects and adenylate cyclase stimulation by (-)-noradrenaline and (-)-adrenaline

1 reference

https://pubmed.ncbi.nlm.nih.gov/12010770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The beta 1-adrenoceptor antagonist CGP 20712 A unmasks beta 2-adrenoceptors activated by (-)-adrenaline in rat sinoatrial node

1 reference

https://pubmed.ncbi.nlm.nih.gov/12010770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pertussis toxin inhibits negative inotropic and negative chronotropic muscarinic cholinergic effects on the heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/12010770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta 2-adrenoceptor-mediated positive inotropic effect of adrenaline in human ventricular myocardium. Quantitative discrepancies with binding and adenylate cyclase stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12010770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carbachol depolarizes and accelerates pacemaker activity in the sinoatrial node of chicks treated with pertussis toxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12010770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increase in myocardial Gi-proteins in heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/12010770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparison of the effects of adrenaline and noradrenaline on human heart: the role of beta 1- and beta 2-adrenoceptors in the stimulation of adenylate cyclase and contractile force

1 reference

https://pubmed.ncbi.nlm.nih.gov/12010770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective beta 1-adrenoceptor blockade enhances positive inotropic responses to endogenous catecholamines mediated through beta 2-adrenoceptors in human atrial myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/12010770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional differences of beta 1- and beta 2-adrenoceptor-mediated functions in feline heart. A beta 2-adrenoceptor-mediated positive inotropic effect possibly unrelated to cyclic AMP

1 reference

https://pubmed.ncbi.nlm.nih.gov/12010770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased messenger RNA level of the inhibitory G protein alpha subunit Gi alpha-2 in human end-stage heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/12010770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coexistence of functioning beta 1- and beta 2-adrenoceptors in single myocytes from human ventricle

1 reference

https://pubmed.ncbi.nlm.nih.gov/12010770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pertussis toxin-induced ADP ribosylation of inhibitor G proteins alters vagal control of heart rate in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/12010770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional coupling of the beta 2-adrenoceptor to a pertussis toxin-sensitive G protein in cardiac myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12010770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The beta-adrenoceptor subtype(s) mediating adrenaline- and dobutamine-induced blood pressure and heart rate changes in healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/12010770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Response of failing canine and human heart cells to beta 2-adrenergic stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12010770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Do beta 2-adrenergic receptors modulate Ca2+ in adult rat ventricular myocytes?

1 reference

https://pubmed.ncbi.nlm.nih.gov/12010770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of (Gialpha) proteins increases arrhythmogenic effects of beta-adrenergic stimulation in the heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/12010770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of beta2-adrenergic receptors hastens relaxation and mediates phosphorylation of phospholamban, troponin I, and C-protein in ventricular myocardium from patients with terminal heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/12010770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coupling of beta2-adrenoceptor to Gi proteins and its physiological relevance in murine cardiac myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12010770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Muscarinic and beta-adrenergic regulation of heart rate, force of contraction and calcium current is preserved in mice lacking endothelial nitric oxide synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12010770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coupling function of endogenous alpha(1)- and beta-adrenergic receptors in mouse cardiomyocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12010770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of G-protein signaling in ventricular myocytes from the adult mouse heart: differences from the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/12010770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Both beta(2)- and beta(1)-adrenergic receptors mediate hastened relaxation and phosphorylation of phospholamban and troponin I in ventricular myocardium of Fallot infants, consistent with selective coupling of beta(2)-adrenergic receptors to G(s)-pr

1 reference

https://pubmed.ncbi.nlm.nih.gov/12010770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta 2-adrenoceptor activation by zinterol causes protein phosphorylation, contractile effects and relaxant effects through a cAMP pathway in human atrium

1 reference

https://pubmed.ncbi.nlm.nih.gov/12010770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Convenient apparatus for recording contractions of isolated heart muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/12010770

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.BJP.0704700

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

2 November 2017

ResearchGate publication ID

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