(Q42547789)

English

Immunochemical, 32P-postlabeling, and GC/MS detection of 4-aminobiphenyl-DNA adducts in human peripheral lung in relation to metabolic activation pathways involving pulmonary N-oxidation, conjugation, and peroxidation.

scientific article published on August 1997

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5 November 2019

Immunochemical, 32P-postlabeling, and GC/MS detection of 4-aminobiphenyl-DNA adducts in human peripheral lung in relation to metabolic activation pathways involving pulmonary N-oxidation, conjugation, and peroxidation (English)

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S J Culp

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D W Roberts

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G Talaska

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N P Lang

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P P Fu

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C H Teitel

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J E Snawder

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L S Von Tungeln

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F F Kadlubar

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1 August 1997

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Mutation Research

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5 November 2019

Smoking related carcinogen-DNA adducts in biopsy samples of human urinary bladder: identification of N-(deoxyguanosin-8-yl)-4-aminobiphenyl as a major adduct

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Localization, distribution, and induction of xenobiotic-metabolizing enzymes and aryl hydrocarbon hydroxylase activity within lung

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Correlation of DNA adduct levels in human lung with cigarette smoking

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Carcinogen metabolism and DNA adducts in human lung tissues as affected by tobacco smoking or metabolic phenotype: a case-control study on lung cancer patients.

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Advantages and limitations of laboratory methods for measurement of carcinogen-DNA adducts for epidemiological studies

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Immunoaffinity concentration of human lung DNA adducts using an anti-benzo[a]pyrene-diol-epoxide-DNA antibody. Analysis by 32P-postlabelling or ELISA.

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Human lung carcinogen-DNA adduct levels mediated by genetic polymorphisms in vivo

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Analysis of 4-aminobiphenyl-DNA adducts in human urinary bladder and lung by alkaline hydrolysis and negative ion gas chromatography-mass spectrometry

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Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines

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Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon

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Metabolic activation of the N-hydroxy derivative of the carcinogen 4-aminobiphenyl by human tissue sulfotransferases.

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N-and O-acetylation of aromatic and heterocyclic amine carcinogens by human monomorphic and polymorphic acetyltransferases expressed in COS-1 cells

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Mechanism of formation and structural characterization of DNA adducts derived from peroxidative activation of benzidine

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Assembly of dimeric myeloperoxidase during posttranslational maturation in human leukemic HL-60 cells

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3,3',5,5' - Tetramethylbenzidine as an Ames test negative chromogen for horse-radish peroxidase in enzyme-immunoassay

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32P-postlabelling and mass spectrometric methods for analysis of bulky, polyaromatic carcinogen-DNA adducts in humans

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Arylamine-DNA adducts in vitro and in vivo: their role in bacterial mutagenesis and urinary bladder carcinogenesis

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Peroxidase-mediated irreversible binding of arylamine carcinogens to DNA in intact polymorphonuclear leukocytes activated by a tumor promoter

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Reactivity of benzidine diimine with DNA to form N-(deoxyguanosin-8-yl)-benzidine

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The formation of 2-aminofluorene-DNA adducts in vivo: evidence for peroxidase-mediated activation

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The oxidation of 4-aminobiphenyl by horseradish peroxidase

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Myeloperoxidase-catalyzed binding of 3-amino-1-methyl-5H-pyrido[4,3-b]indole, a tryptophan pyrolysis product, to protein

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10.1016/S0027-5107(97)00101-2

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5 November 2019

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5 November 2019

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