(Q42560642)

English

Thromboxane (Tx) A2 receptor blockade and TxA2 synthase inhibition alone and in combination: comparison of anti-aggregatory efficacy in human platelets

scientific article published on February 1, 1991

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

2 November 2017

Thromboxane (Tx) A2 receptor blockade and TxA2 synthase inhibition alone and in combination: comparison of anti-aggregatory efficacy in human platelets (English)

1 reference

10.1111/J.1476-5381.1991.TB12200.X

https://api.crossref.org/works/10.1111/J.1476-5381.1991.TB12200.X

3 December 2022

1 reference

10.1111/J.1476-5381.1991.TB12200.X

https://api.crossref.org/works/10.1111/J.1476-5381.1991.TB12200.X

3 December 2022

author name string

I. S. Watts

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1826620

3 December 2022

K. A. Wharton

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1826620

3 December 2022

B. P. White

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1826620

3 December 2022

P. Lumley

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1826620

3 December 2022

language of work or name

0 references

publication date

1 February 1991

1 reference

Europe PubMed Central

2 November 2017

full work available at URL

https://europepmc.org/articles/PMC1918008

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1826620

3 December 2022

https://europepmc.org/articles/PMC1918008?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1826620

3 December 2022

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1476-5381.1991.tb12200.x

1 reference

10.1111/J.1476-5381.1991.TB12200.X

https://api.crossref.org/works/10.1111/J.1476-5381.1991.TB12200.X

3 December 2022

http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1476-5381.1991.tb12200.x/fullpdf

1 reference

10.1111/J.1476-5381.1991.TB12200.X

https://api.crossref.org/works/10.1111/J.1476-5381.1991.TB12200.X

3 December 2022

British Journal of Pharmacology

1 reference

Europe PubMed Central

2 November 2017

102

1 reference

Europe PubMed Central

2 November 2017

2

1 reference

Europe PubMed Central

2 November 2017

497-505

1 reference

Europe PubMed Central

2 November 2017

Some quantitative uses of drug antagonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1918008

28 May 2018

Endogenous prostacyclin biosynthesis and platelet function during selective inhibition of thromboxane synthase in man.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1918008

28 May 2018

Potentiation by dazoxiben, a thromboxane synthetase inhibitor, of platelet aggregation inhibitory activity of a thromboxane receptor antagonist and of prostacyclin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1918008

28 May 2018

Studies on the characterisation of prostanoid receptors: a proposed classification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1918008

28 May 2018

Inhibition of thromboxane synthetase does not necessarily prevent platelet aggregation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1918008

28 May 2018

The biochemical pharmacology of thromboxane synthase inhibition in man.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1918008

28 May 2018

Prostaglandin endoperoxides modulate the response to thromboxane synthase inhibition during coronary thrombosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1918008

28 May 2018

Thromboxane A2 biosynthesis in human disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1918008

28 May 2018

Interaction of blood platelets with the vessel wall

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1918008

28 May 2018

The thromboxane A2/prostaglandin endoperoxide receptor antagonist activity of CV-4151, a thromboxane A2 synthetase inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1918008

28 May 2018

Role of proaggregatory and antiaggregatory prostaglandins in hemostasis. Studies with combined thromboxane synthase inhibition and thromboxane receptor antagonism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1918008

28 May 2018

In vivo synthesis of thromboxane and prostacyclin in man in health and disease. Data from GC-MS measurements of major urinary metabolites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1918008

28 May 2018

Prostaglandin H2 in human platelet activation: coactivator and substitute for thromboxane A2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1918008

28 May 2018

GR32191, a highly potent and specific thromboxane A2 receptor blocking drug on platelets and vascular and airways smooth muscle in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1918008

28 May 2018

AH6809, a prostaglandin DP-receptor blocking drug on human platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1918008

28 May 2018

Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1918008

28 May 2018

The distribution and metabolism of arachidonic acid in rabbit platelets during aggregation and its modification by drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1918008

28 May 2018

Acetylation of prostaglandin synthase by aspirin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1918008

28 May 2018

Mechanisms of platelet shape change, aggregation, and release induced by collagen, thrombin, or A23,187

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1918008

28 May 2018

13-Azaprostanoic acid: a specific antagonist of the human blood platelet thromboxane/endoperoxide receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1918008

28 May 2018

Thromboxane synthase inhibition causes re-direction of prostaglandin endoperoxides to prostaglandin D2 during collagen stimulated aggregation of human platelet rich plasma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1918008

16 August 2018

A thromboxane synthetase inhibitor reorients endoperoxide metabolism in whole blood towards prostacyclin and prostaglandin E2

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.1991.TB12200.X

21 January 2018

Thromboxane synthase inhibition combined with thromboxane receptor blockade: a step forward in antithrombotic strategy?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1918008

1 December 2018

A method for quantitating platelet aggregation and analyzing drug-receptor interactions on platelets in whole blood in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/1826620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platelet interaction with collagen fibrils in flowing blood. I. Reaction of human platelets with alpha chymotrypsin-digested subendothelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/1826620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

R 68 070: thromboxane A2 synthetase inhibition and thromboxane A2/prostaglandin endoperoxide receptor blockade combined in one molecule--I. Biochemical profile in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/1826620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CV-4151--a potent, selective thromboxane A2 synthetase inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/1826620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of multiple thromboxane metabolites in plasma and urine

1 reference

https://pubmed.ncbi.nlm.nih.gov/1826620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inhibitory effect of GR32191, a thromboxane receptor blocking drug, on human platelet aggregation, adhesion and secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/1826620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The response to thromboxane A2 analogues in human platelets. Discrimination of two binding sites linked to distinct effector systems

1 reference

https://pubmed.ncbi.nlm.nih.gov/1826620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preliminary assessment of a novel thromboxane A2 receptor-blocking drug, GR32191, in healthy subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/1826620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that prostaglandin endoperoxides can induce platelet aggregation in the absence of thromboxane A2 production

1 reference

https://pubmed.ncbi.nlm.nih.gov/1826620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Administration to man of UK-37,248-01, a selective inhibitor of thromboxane synthetase

1 reference

https://pubmed.ncbi.nlm.nih.gov/1826620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thromboxane synthetase inhibition as antithrombotic strategy

1 reference

https://pubmed.ncbi.nlm.nih.gov/1826620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role of calcium-activated phospholipid-dependent protein kinase in human platelet activation. Comparison of thrombin and collagen actions

1 reference

https://pubmed.ncbi.nlm.nih.gov/1826620

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preliminary clinical studies with thromboxane synthase inhibitors and thromboxane receptor blockers. A review

9

1 reference

10.1111/J.1476-5381.1991.TB12200.X

https://api.crossref.org/works/10.1111/J.1476-5381.1991.TB12200.X

3 December 2022

Pathophysiological actions of thromboxane A2 and their pharmacological antagonism by thromboxane receptor blockade with GR32191

21

1 reference

10.1111/J.1476-5381.1991.TB12200.X

https://api.crossref.org/works/10.1111/J.1476-5381.1991.TB12200.X

3 December 2022

Maximal blockade of TxA2 without compromised PGI2 formation; a superior profile of the TxA2 receptor blocking drug GR32191 over aspirin

29

1 reference

10.1111/J.1476-5381.1991.TB12200.X

https://api.crossref.org/works/10.1111/J.1476-5381.1991.TB12200.X

3 December 2022

Identifiers

10.1111/J.1476-5381.1991.TB12200.X

1 reference

Europe PubMed Central

2 November 2017

1 reference

Europe PubMed Central

2 November 2017

1 reference

Europe PubMed Central

2 November 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q42560642&oldid=2137190044"