(Q42561612)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23321985%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

title

Inhibition of N-terminal ATPase on HSP90 attenuates colitis through enhanced Treg function (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23321985%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

7

1 reference

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22 February 2020

author name string

C B Collins

1

1 reference

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22 February 2020

C M Aherne

2

1 reference

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22 February 2020

A Yeckes

3

1 reference

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22 February 2020

K Pound

4

1 reference

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22 February 2020

H K Eltzschig

5

1 reference

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22 February 2020

P Jedlicka

6

1 reference

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22 February 2020

publication date

16 January 2013

1 reference

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22 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23321985%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

volume

6

1 reference

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22 February 2020

issue

5

1 reference

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22 February 2020

page(s)

960-971

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23321985%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/mi.2012.134

22 February 2020

exact match

0 references

cites work

HSF1 is a transcriptional activator of IL-10 gene expression in RAW264.7 macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748235

Hsp10, Hsp70, and Hsp90 immunohistochemical levels change in ulcerative colitis after therapy

28 May 2018

1 reference

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Flt3 ligand expands CD103⁺ dendritic cells and FoxP3⁺ T regulatory cells, and attenuates Crohn's-like murine ileitis

28 May 2018

1 reference

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Retinoic acid attenuates ileitis by restoring the balance between T-helper 17 and T regulatory cells.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748235

A compound that inhibits the HOP-Hsp90 complex formation and has unique killing effects in breast cancer cell lines

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748235

Histone deacetylase 6 and heat shock protein 90 control the functions of Foxp3(+) T-regulatory cells

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748235

EC144, a synthetic inhibitor of heat shock protein 90, blocks innate and adaptive immune responses in models of inflammation and autoimmunity

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748235

Inhibition of HDAC9 increases T regulatory cell function and prevents colitis in mice.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748235

A role for HSP70 in protecting against indomethacin-induced gastric lesions

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748235

IL-10 is critically involved in mycobacterial HSP70 induced suppression of proteoglycan-induced arthritis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748235

Heat shock transcription factor 1-activating compounds suppress polyglutamine-induced neurodegeneration through induction of multiple molecular chaperones

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748235

Release of heat shock protein 70 and the effects of extracellular heat shock protein 70 on the production of IL-10 in fibroblast-like synoviocytes

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748235

Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748235

HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748235

Heat shock protein 90 inhibitors prolong survival, attenuate inflammation, and reduce lung injury in murine sepsis

28 May 2018

1 reference

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Diverse effects of Stat1 on the regulation of hsp90alpha gene under heat shock

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748235

Inhibition of Hsp90 attenuates inflammation in endotoxin-induced uveitis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748235

Phosphorylation of HSF1 by MAPK-activated protein kinase 2 on serine 121, inhibits transcriptional activity and promotes HSP90 binding

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748235

Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748235

Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748235

Heat shock factor 1 represses transcription of the IL-1beta gene through physical interaction with the nuclear factor of interleukin 6

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748235

Induction of a heat shock factor 1-dependent stress response alters the cytotoxic activity of hsp90-binding agents.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748235

The heat shock protein 90 antagonist novobiocin interacts with a previously unrecognized ATP-binding domain in the carboxyl terminus of the chaperone

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748235

An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748235

Non-steroidal anti-inflammatory drugs inhibit the expression of cytokines and induce HSP70 in human monocytes

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748235

Heat shock proteins and regulation of cytokine expression

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748235

Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748235

Interleukin 10 is a growth factor for a population of regulatory T cells

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748235

The hsp90-based chaperone system: involvement in signal transduction from a variety of hormone and growth factor receptors

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748235

Regulatory interactions between CD45RBhigh and CD45RBlow CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748235

Induction of IL-10 and inhibition of experimental arthritis are specific features of microbial heat shock proteins that are absent for other evolutionarily conserved immunodominant proteins

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3748235

Infection with a helminth parasite prevents experimental colitis via a macrophage-mediated mechanism

16 August 2018

1 reference

12 December 2020

The heat-shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin suppresses glial inflammatory responses and ameliorates experimental autoimmune encephalomyelitis

1 reference

12 December 2020

Heat shock protein gene 70-2 polymorphism is differentially associated with the clinical phenotypes of ulcerative colitis and Crohn's disease

1 reference

12 December 2020

Genetic evidence for a protective role for heat shock factor 1 and heat shock protein 70 against colitis

1 reference

12 December 2020

Exaggerated human monocyte IL-10 concomitant to minimal TNF-alpha induction by heat-shock protein 27 (Hsp27) suggests Hsp27 is primarily an antiinflammatory stimulus

1 reference

12 December 2020

Control of intestinal inflammation by regulatory T cells

1 reference

12 December 2020

Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD)

1 reference

12 December 2020

Effect of preinduction of heat shock proteins on acetic acid-induced colitis in rats

1 reference

12 December 2020

Identifiers

DOI

10.1038/MI.2012.134

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23321985%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23321985%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

PubMed publication ID

23321985

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23321985%20AND%20SRC:MED&resulttype=core&format=json