(Q42581400)

English

Biochemical, functional, and pharmacological characterization of AT-56, an orally active and selective inhibitor of lipocalin-type prostaglandin D synthase

scientific article published on 8 January 2009

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

3 November 2017

Biochemical, functional, and pharmacological characterization of AT-56, an orally active and selective inhibitor of lipocalin-type prostaglandin D synthase (English)

1 reference

Europe PubMed Central

PMC publication ID

3 November 2017

1 reference

based on heuristic

inferred from title

author name string

Daisuke Irikura

1

1 reference

Europe PubMed Central

PMC publication ID

3 November 2017

Kosuke Aritake

2

1 reference

Europe PubMed Central

PMC publication ID

3 November 2017

Nanae Nagata

3

1 reference

Europe PubMed Central

PMC publication ID

3 November 2017

Toshihiko Maruyama

4

1 reference

Europe PubMed Central

PMC publication ID

3 November 2017

Shigeru Shimamoto

5

1 reference

Europe PubMed Central

PMC publication ID

3 November 2017

Yoshihiro Urade

6

1 reference

Europe PubMed Central

PMC publication ID

3 November 2017

language of work or name

0 references

publication date

8 January 2009

1 reference

Europe PubMed Central

PMC publication ID

3 November 2017

number of pages

8

1 reference

based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

3 November 2017

284

1 reference

Europe PubMed Central

PMC publication ID

3 November 2017

12

1 reference

Europe PubMed Central

PMC publication ID

3 November 2017

7623-7630

1 reference

Europe PubMed Central

PMC publication ID

3 November 2017

NMR solution structure of lipocalin-type prostaglandin D synthase: evidence for partial overlapping of catalytic pocket and retinoic acid-binding pocket within the central cavity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

A novel pathway to enhance adipocyte differentiation of 3T3-L1 cells by up-regulation of lipocalin-type prostaglandin D synthase mediated by liver X receptor-activated sterol regulatory element-binding protein-1c

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Lipocalin-type prostaglandin D synthase/beta-trace is a major amyloid beta-chaperone in human cerebrospinal fluid.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Lipocalin-type prostaglandin D synthase produces prostaglandin D2 involved in regulation of physiological sleep.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Essential role for hematopoietic prostaglandin D2 synthase in the control of delayed type hypersensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Structural and functional characterization of HQL-79, an orally selective inhibitor of human hematopoietic prostaglandin D synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Prostaglandin D2 induces nuclear import of the sex-determining factor SOX9 via its cAMP-PKA phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Mechanism of metal activation of human hematopoietic prostaglandin D synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Lipocalin-type and hematopoietic prostaglandin D synthases as a novel example of functional convergence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Dominant localization of prostaglandin D receptors on arachnoid trabecular cells in mouse basal forebrain and their involvement in the regulation of non-rapid eye movement sleep

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Biochemical, structural, genetic, physiological, and pathophysiological features of lipocalin-type prostaglandin D synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Cellular localization of lipocalin-type prostaglandin D synthase (beta-trace) in the central nervous system of the adult rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Prostaglandin D synthase gene is involved in the regulation of non-rapid eye movement sleep

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Prostaglandin D synthase: structure and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Binding of biliverdin, bilirubin, and thyroid hormones to lipocalin-type prostaglandin D synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Lack of tactile pain (allodynia) in lipocalin-type prostaglandin D synthase-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Lipocalin-type prostaglandin D synthase in human male reproductive organs and seminal plasma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Expression of lipocalin-type prostaglandin D synthase (beta-trace) in human heart and its accumulation in the coronary circulation of angina patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Prostaglandin D synthase in human megakaryoblastic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Cloning and crystal structure of hematopoietic prostaglandin D synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Lipocalin-type prostaglandin D synthase (beta-trace) is a newly recognized type of retinoid transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Beta-trace gene expression is regulated by a core promoter and a distal thyroid hormone response element

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Lipocalin-type prostaglandin D synthase (beta-trace) is located in pigment epithelial cells of rat retina and accumulates within interphotoreceptor matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Purification and chemical characterization of beta-trace protein from human cerebrospinal fluid: its identification as prostaglandin D synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Molecular characterization of a mouse prostaglandin D receptor and functional expression of the cloned gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Prostaglandin D2 induces sleep when microinjected into the preoptic area of conscious rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Prostaglandin D2 generation after activation of rat and human mast cells with anti-IgE.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Purification and characterization of rat brain prostaglandin D synthetase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Homology and structure-function correlations between alpha 1-acid glycoprotein and serum retinol-binding protein and its relatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Inhibition of sleep in rats by inorganic selenium compounds, inhibitors of prostaglandin D synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Human brain prostaglandin D synthase has been evolutionarily differentiated from lipophilic-ligand carrier proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Purification and characterisation of prostaglandin endoperoxide D-isomerase, a cytoplasmic, glutathione-requiring enzymE

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

28 May 2018

Enhancement of prostaglandin D(2) production through cyclooxygenase-2 and lipocalin-type prostaglandin D synthase by upstream stimulatory factor 1 in human brain-derived TE671 cells under serum starvation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

16 August 2018

Lipocalin-type prostaglandin D synthase is up-regulated in oligodendrocytes in lysosomal storage diseases and binds gangliosides.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

16 August 2018

Accelerated glucose intolerance, nephropathy, and atherosclerosis in prostaglandin D2 synthase knock-out mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

16 August 2018

Cloning, expression, crystallization, and preliminary X-ray analysis of recombinant mouse lipocalin-type prostaglandin D synthase, a somnogen-producing enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

16 August 2018

Characterization of the unfolding process of lipocalin-type prostaglandin D synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

16 August 2018

Biochemical characterization of mouse microsomal prostaglandin E synthase-1 and its colocalization with cyclooxygenase-2 in peritoneal macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

16 August 2018

Identification of a fertility-associated protein in bull seminal plasma as lipocalin-type prostaglandin D synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

16 August 2018

Identification of beta-trace as prostaglandin D synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

16 August 2018

Inhibition of rat brain prostaglandin D synthase by inorganic selenocompounds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658056

16 August 2018

Knockout of the l-pgds gene aggravates obesity and atherosclerosis in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19131342

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and assay of PGH synthase from bovine seminal vesicles

1 reference

https://pubmed.ncbi.nlm.nih.gov/19131342

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical and immunological characterization of rat spleen prostaglandin D synthetase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19131342

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical and immunological demonstration of prostaglandin D2, E2, and F2 alpha formation from prostaglandin H2 by various rat glutathione S-transferase isozymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19131342

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies of protein-ligand interactions by NMR

1 reference

https://pubmed.ncbi.nlm.nih.gov/19131342

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CRTH2, an orphan receptor of T-helper-2-cells, is expressed on basophils and eosinophils and responds to mast cell-derived factor(s)

1 reference

https://pubmed.ncbi.nlm.nih.gov/19131342

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Increased incidence of renal papillary necrosis in autopsy material.]

1 reference

https://pubmed.ncbi.nlm.nih.gov/19131342

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prostaglandin D2 as a mediator of allergic asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19131342

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stage and region-specific localization of lipocalin-type prostaglandin D synthase in the adult murine testis and epididymis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19131342

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pronounced eosinophilic lung inflammation and Th2 cytokine release in human lipocalin-type prostaglandin D synthase transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19131342

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M808593200

1 reference

Europe PubMed Central

PMC publication ID

3 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

3 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

3 November 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q42581400&oldid=1962175636"