(Q42594428)

3 November 2017

APC loss-induced intestinal tumorigenesis in Drosophila: Roles of Ras in Wnt signaling activation and tumor progression (English)

1 reference

3 November 2017

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1 reference

Chenhui Wang

1

1 reference

3 November 2017

Rui Zhao

2

1 reference

3 November 2017

Pin Huang

3

1 reference

3 November 2017

Fu Yang

4

1 reference

3 November 2017

Zhenghui Quan

5

1 reference

3 November 2017

Na Xu

6

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3 November 2017

Rongwen Xi

7

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3 November 2017

language of work or name

English

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publication date

6 April 2013

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3 November 2017

19

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based on heuristic

inferred from page(s)

published in

Developmental Biology

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3 November 2017

378

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3 November 2017

2

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3 November 2017

122-140

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Regulation of armadillo by a Drosophila APC inhibits neuronal apoptosis during retinal development

3 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Drosophila APC2 and APC1 play overlapping roles in wingless signaling in the embryo and imaginal discs.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Drosophila APC2 and APC1 have overlapping roles in the larval brain despite their distinct intracellular localizations.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

A target-selected Apc-mutant rat kindred enhances the modeling of familial human colon cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Subcellular distribution of Wnt pathway proteins in normal and neoplastic colon

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Developmental regulation of expression and activity of multiple forms of the Drosophila RAC protein kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Linking colorectal cancer to Wnt signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Maintaining tissue homeostasis: dynamic control of somatic stem cell activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

EGF signaling regulates the proliferation of intestinal stem cells in Drosophila

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Prevalence of ras gene mutations in human colorectal cancers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Raf acts downstream of the EGF receptor to determine dorsoventral polarity during Drosophila oogenesis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Intestinal stem cells in mammals and Drosophila

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Activation of wingless targets requires bipartite recognition of DNA by TCF

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Wnt/beta-catenin signaling in development and disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Cellular metabolism and disease: what do metabolic outliers teach us?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Nuclear beta-catenin expression and Wnt signalling: in defence of the dogma.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Detection of high incidence of K-ras oncogenes during human colon tumorigenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Identification and characterization of the familial adenomatous polyposis coli gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

A Drosophila APC tumour suppressor homologue functions in cellular adhesion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Novel roles for APC family members and Wingless/Wnt signaling during Drosophila brain development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

PTEN-deficient intestinal stem cells initiate intestinal polyposis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

APC and oncogenic KRAS are synergistic in enhancing Wnt signaling in intestinal tumor formation and progression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Intestinal stem cells in the adult Drosophila midgut

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

EGFR/Ras/MAPK signaling mediates adult midgut epithelial homeostasis and regeneration in Drosophila

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Tyrosine phosphorylation regulates the adhesions of ras-transformed breast epithelia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Identification of FAP locus genes from chromosome 5q21

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Mosaic analysis with a repressible cell marker (MARCM) for Drosophila neural development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Adenomatous polyposis coli regulates Drosophila intestinal stem cell proliferation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Polycomb group genes Psc and Su(z)2 restrict follicle stem cell self-renewal and extrusion by controlling canonical and noncanonical Wnt signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Paracrine Wingless signalling controls self-renewal of Drosophila intestinal stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Paracrine unpaired signaling through the JAK/STAT pathway controls self-renewal and lineage differentiation of drosophila intestinal stem cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Mutated K-ras(Asp12) promotes tumourigenesis in Apc(Min) mice more in the large than the small intestines, with synergistic effects between K-ras and Wnt pathways.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Wnt/beta-catenin signaling: components, mechanisms, and diseases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Drosophila APC2 and Armadillo participate in tethering mitotic spindles to cortical actin.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Testing hypotheses for the functions of APC family proteins using null and truncation alleles in Drosophila

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Evidence that stem cells reside in the adult Drosophila midgut epithelium.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Coordination of growth and cell division in the Drosophila wing.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Oncogenic KRAS is not necessary for Wnt signalling activation in APC-associated FAP adenomas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

The adult Drosophila posterior midgut is maintained by pluripotent stem cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

A two-step model for colon adenoma initiation and progression caused by APC loss

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

APC mutations occur early during colorectal tumorigenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Importance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Loss of Apc allows phenotypic manifestation of the transforming properties of an endogenous K-ras oncogene in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

The adult Drosophila gastric and stomach organs are maintained by a multipotent stem cell pool at the foregut/midgut junction in the cardia (proventriculus).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Quiescent gastric stem cells maintain the adult Drosophila stomach

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

The behaviour of Drosophila adult hindgut stem cells is controlled by Wnt and Hh signalling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Combinatorial chemoprevention of intestinal neoplasia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

A novel role for an APC2-Diaphanous complex in regulating actin organization in Drosophila

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

EGFR, Wingless and JAK/STAT signaling cooperatively maintain Drosophila intestinal stem cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta -catenin signaling is activated in human colon tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

Apical constriction and invagination downstream of the canonical Wnt signaling pathway require Rho1 and Myosin II.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2013.03.020

10.1016/J.YDBIO.2013.03.020

7 January 2021

Identifiers

DOI

1 reference

3 November 2017

1 reference