(Q42596186)

English

Tim-4 inhibition of T-cell activation and T helper type 17 differentiation requires both the immunoglobulin V and mucin domains and occurs via the mitogen-activated protein kinase pathway

scientific article published on 5 April 2011

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 November 2017

Tim-4 inhibition of T-cell activation and T helper type 17 differentiation requires both the immunoglobulin V and mucin domains and occurs via the mitogen-activated protein kinase pathway (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 November 2017

author name string

Wei Cao

1

1 reference

Europe PubMed Central

PubMed publication ID

3 November 2017

Michelle Ryan

2

1 reference

Europe PubMed Central

PubMed publication ID

3 November 2017

Deirdre Buckley

3

1 reference

Europe PubMed Central

PubMed publication ID

3 November 2017

Rosemary O'Connor

4

1 reference

Europe PubMed Central

PubMed publication ID

3 November 2017

Michael R Clarkson

5

1 reference

Europe PubMed Central

PubMed publication ID

3 November 2017

publication date

5 April 2011

1 reference

Europe PubMed Central

PubMed publication ID

3 November 2017

1 reference

Europe PubMed Central

PubMed publication ID

3 November 2017

133

1 reference

Europe PubMed Central

PubMed publication ID

3 November 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

3 November 2017

179-189

1 reference

Europe PubMed Central

PubMed publication ID

3 November 2017

Phosphatidylserine receptor Tim-4 is essential for the maintenance of the homeostatic state of resident peritoneal macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088980

30 September 2018

T and B cell hyperactivity and autoimmunity associated with niche-specific defects in apoptotic body clearance in TIM-4-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088980

30 September 2018

Pharmacologic inhibition of MEK-ERK signaling enhances Th17 differentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088980

30 September 2018

ERK-dependent T cell receptor threshold calibration in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088980

30 September 2018

TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088980

30 September 2018

Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088980

30 September 2018

The phosphatidylserine receptor TIM-4 does not mediate direct signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088980

30 September 2018

Induction, function and regulation of IL-17-producing T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088980

30 September 2018

STAT-3 and ERK 1/2 phosphorylation are critical for T-cell alloactivation and graft-versus-host disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088980

30 September 2018

T cell Ig and mucin domain-1-mediated T cell activation requires recruitment and activation of phosphoinositide 3-kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088980

30 September 2018

Loss of STAT3 in CD4+ T cells prevents development of experimental autoimmune diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088980

30 September 2018

TIM-4 expressed on APCs induces T cell expansion and survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088980

30 September 2018

Identification of Tim4 as a phosphatidylserine receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088980

30 September 2018

IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088980

30 September 2018

Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088980

30 September 2018

Structures of T Cell immunoglobulin mucin receptors 1 and 2 reveal mechanisms for regulation of immune responses by the TIM receptor family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088980

30 September 2018

Inhibition of in vitro and in vivo T cell responses by recombinant human Tim-1 extracellular domain proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088980

30 September 2018

Differential role of MAPK signaling in human dendritic cell maturation and Th1/Th2 engagement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088980

30 September 2018

TIM-4 is the ligand for TIM-1, and the TIM-1-TIM-4 interaction regulates T cell proliferation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088980

30 September 2018

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088980

30 September 2018

The TIM gene family: emerging roles in immunity and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088980

30 September 2018

Identification of a factor that links apoptotic cells to phagocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088980

30 September 2018

MAP kinases in the immune response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088980

30 September 2018

Mechanisms of phosphatidylserine exposure, a phagocyte recognition signal, on apoptotic T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088980

30 September 2018

Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088980

30 September 2018

Cutting edge: An in vivo requirement for STAT3 signaling in TH17 development and TH17-dependent autoimmunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bimodal regulation of T cell-mediated immune responses by TIM-4

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ras-ERK MAPK cascade regulates GATA3 stability and Th2 differentiation through ubiquitin-proteasome pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Galectin-9 significantly prolongs the survival of fully mismatched cardiac allografts in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21463297

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2567.2011.03424.X

1 reference

Europe PubMed Central

PubMed publication ID

3 November 2017

PMC publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 November 2017

ResearchGate publication ID

0 references

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