(Q42598575)

3 November 2017

title

Conformational changes mediate interleukin-10 receptor 2 (IL-10R2) binding to IL-10 and assembly of the signaling complex (English)

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interleukin-10 receptor complex

3 November 2017

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Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1905571

Interleukin 10 receptor subunit beta

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Interleukin 10

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Interleukin 10 receptor subunit alpha

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positive regulation of receptor signaling pathway via JAK-STAT

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author

Raymond P. Donnelly

4

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3 November 2017

Sung Il Yoon

1

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3 November 2017

Naomi J Logsdon

2

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3 November 2017

Faruk Sheikh

3

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3 November 2017

Mark R Walter

5

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3 November 2017

language of work or name

English

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publication date

18 September 2006

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Journal of Biological Chemistry

3 November 2017

number of pages

9

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based on heuristic

inferred from page(s)

published in

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3 November 2017

volume

281

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3 November 2017

issue

46

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3 November 2017

page(s)

35088-35096

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Interleukin-10 and the interleukin-10 receptor

3 November 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.M606791200

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes

21 January 2018

1 reference

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Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression

21 January 2018

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Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes

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Interleukin 10: a novel stimulatory factor for mast cells and their progenitors

21 January 2018

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The role of interleukin-10 in autoimmune disease: systemic lupus erythematosus (SLE) and multiple sclerosis (MS).

21 January 2018

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Identification and functional characterization of a second chain of the interleukin-10 receptor complex

21 January 2018

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Two distinct domains within the N-terminal region of Janus kinase 1 interact with cytokine receptors

21 January 2018

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Comparison of interleukin-22 and interleukin-10 soluble receptor complexes

21 January 2018

1 reference

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Same structure, different function crystal structure of the Epstein-Barr virus IL-10 bound to the soluble IL-10R1 chain

21 January 2018

1 reference

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Hijacking and exploitation of IL-10 by intracellular pathogens

21 January 2018

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Primate cytomegaloviruses encode and express an IL-10-like protein

21 January 2018

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Human cytomegalovirus harbors its own unique IL-10 homolog (cmvIL-10)

21 January 2018

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Structural analysis of IL-10 and Type I interferon family members and their complexes with receptor

21 January 2018

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Interleukin-10 and related cytokines and receptors

21 January 2018

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The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain

21 January 2018

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The IL-10R2 binding hot spot on IL-22 is located on the N-terminal helix and is dependent on N-linked glycosylation

21 January 2018

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Is there an interaction between interleukin-10 and interleukin-22?

21 January 2018

1 reference

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Crystal structure of the IL-10/IL-10R1 complex reveals a shared receptor binding site

21 January 2018

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Purification, crystallization and preliminary X-ray diffraction of a complex between IL-10 and soluble IL-10R1.

21 January 2018

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Advances in surface plasmon resonance biosensor analysis

21 January 2018

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Interferons inhibit activation of STAT6 by interleukin 4 in human monocytes by inducing SOCS-1 gene expression

21 January 2018

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Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

21 January 2018

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Interactions among the components of the interleukin-10 receptor complex

21 January 2018

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Noncompetitive antibody neutralization of IL-10 revealed by protein engineering and x-ray crystallography

21 January 2018

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A model of the ternary complex of interleukin-10 with its soluble receptors

21 January 2018

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Hexameric structure and assembly of the interleukin-6/IL-6 alpha-receptor/gp130 complex

21 January 2018

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Crystal structure of human interleukin-10 at 1.6 A resolution and a model of a complex with its soluble receptor

21 January 2018

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Crystal structure of human cytomegalovirus IL-10 bound to soluble human IL-10R1.

21 January 2018

1 reference

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Crystallization and X-ray diffraction analysis of insect-cell-derived IL-22.

21 January 2018

1 reference

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Crystal structure of recombinant human interleukin-22

21 January 2018

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Temporal associations between interleukin 22 and the extracellular domains of IL-22R and IL-10R2

21 January 2018

1 reference

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Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

21 January 2018

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Site2 binding energetics of the regulatory step of growth hormone-induced receptor homodimerization

21 January 2018

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Structure of the quaternary complex of interleukin-2 with its alpha, beta, and gammac receptors

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M606791200

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3 November 2017

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