(Q42610287)

3 November 2017

Validity and reliability of in vitro systems in safety evaluation (English)

1 reference

3 November 2017

A J Paine

1

1 reference

PubMed ID

21781729

3 November 2017

language of work or name

1 reference

1 October 1996

1 reference

Environmental Toxicology and Pharmacology

3 November 2017

1 reference

3 November 2017

2

1 reference

3 November 2017

2-3

1 reference

3 November 2017

207-212

1 reference

Estradiol metabolism by complementary deoxyribonucleic acid-expressed human cytochrome P450s

3 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1382-6689%2896%2900057-9

7 January 2021

The concentration of cytochrome P-450 in human hepatocyte culture

1 reference

https://api.crossref.org/works/10.1016%2FS1382-6689%2896%2900057-9

7 January 2021

Cytochrome P450 maintenance and diazepam metabolism in cultured rat hepatocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1382-6689%2896%2900057-9

7 January 2021

The effects of dimethylsulphoxide and 5-aminolaevulinic acid on the activities of cytochrome P450-dependent mixed function oxidase and UDP-glucuronosyl transferase activities in human Hep G2 hepatoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1382-6689%2896%2900057-9

7 January 2021

The toxicity of menadione and mitozantrone in human liver-derived Hep G2 hepatoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1382-6689%2896%2900057-9

7 January 2021

Alternatives to animals in toxicity testing.

1 reference

https://api.crossref.org/works/10.1016%2FS1382-6689%2896%2900057-9

7 January 2021

Chloroethylenes: a mechanistic approach to human risk evaluation

1 reference

https://api.crossref.org/works/10.1016%2FS1382-6689%2896%2900057-9

7 January 2021

A new instrument for the rapid preparation of tissue slices

1 reference

https://api.crossref.org/works/10.1016%2FS1382-6689%2896%2900057-9

7 January 2021

Biochemical mechanisms of induction of hepatic peroxisome proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS1382-6689%2896%2900057-9

7 January 2021

Primary cultures and the levels of cytochrome P450 in hepatocytes from mouse, rat, hamster, and rabbit liver

1 reference

https://api.crossref.org/works/10.1016%2FS1382-6689%2896%2900057-9

7 January 2021

Maintenance of total cytochrome P-450 content in rat hepatocyte culture and the abundance of CYP1A2 and CYP2B1/2 mRNAs

1 reference

https://api.crossref.org/works/10.1016%2FS1382-6689%2896%2900057-9

7 January 2021

Altered expression of cytochrome P-450 mRNAs, and potentially of other transcripts encoding key hepatic functions, are triggered during the isolation of rat hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1382-6689%2896%2900057-9

7 January 2021

Effect of amino acids and inducers on the activity of the microsomal mono-oxygenase system in rat liver cell culture

1 reference

https://api.crossref.org/works/10.1016%2FS1382-6689%2896%2900057-9

7 January 2021

The maintenance of cytochrome P-450 in rat hepatocyte culture: some applications of liver cell cultures to the study of drug metabolism, toxicity and the induction of the P-450 system

1 reference

https://api.crossref.org/works/10.1016%2FS1382-6689%2896%2900057-9

7 January 2021

Heterogeneity of cytochrome P450 and its toxicological significance

1 reference

https://api.crossref.org/works/10.1016%2FS1382-6689%2896%2900057-9

7 January 2021

The induction of benzo[a]pyrene-3-mono-oxygenase by singlet oxygen in liver cell culture is mediated by oxidation products of histidine

1 reference

https://api.crossref.org/works/10.1016%2FS1382-6689%2896%2900057-9

7 January 2021

The maintenance of cytochrome P-450 in liver cell culture: recent studies on P-450 mediated mechanisms of toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1382-6689%2896%2900057-9

7 January 2021

Apparent lack of correlation between the loss of cytochrome P-450 in hepatic parenchymal cell culture and the stimulation of haem oxygenase activity

1 reference

https://api.crossref.org/works/10.1016%2FS1382-6689%2896%2900057-9

7 January 2021

The effect of dietary protein and fat on the activity of aryl hydrocarbon hydroxylase in rat liver, kidney and lung.

1 reference

https://api.crossref.org/works/10.1016%2FS1382-6689%2896%2900057-9

7 January 2021

Ligands maintain cytochrome P-450 in liver cell culture by affecting its synthesis and degradation.

1 reference

https://api.crossref.org/works/10.1016%2FS1382-6689%2896%2900057-9

7 January 2021

The application of hepatocyte culture to the identification of pathways of drug metabolism: studies with pindolol and fluperlapine

1 reference

https://api.crossref.org/works/10.1016%2FS1382-6689%2896%2900057-9

7 January 2021

Data-derived safety factors for the evaluation of food additives and environmental contaminants

1 reference

https://api.crossref.org/works/10.1016%2FS1382-6689%2896%2900057-9

7 January 2021

Dynamic organ culture of precision liver slices for in vitro toxicology.

1 reference

https://api.crossref.org/works/10.1016%2FS1382-6689%2896%2900057-9

7 January 2021

Evidence that the loss of rat liver cytochrome P450 in vitro is not solely associated with the use of collagenase, the loss of cell-cell contacts and/or the absence of an extracellular matrix

1 reference

https://api.crossref.org/works/10.1016%2FS1382-6689%2896%2900057-9

7 January 2021

Resistance of precision-cut liver slices to the toxic effects of menadione.

1 reference

https://api.crossref.org/works/10.1016%2FS1382-6689%2896%2900057-9

7 January 2021

10.1016/S1382-6689(96)00057-9

Identifiers

DOI

1 reference

3 November 2017

1 reference

PubMed ID

21781729