(Q42626858)

4 November 2017

title

Association of tamoxifen biliary excretion rate with prior tamoxifen exposure and increased mdr1b expression (English)

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4 November 2017

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Riley J

1

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4 November 2017

Styles J

2

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4 November 2017

Verschoyle RD

3

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4 November 2017

Stanley LA

4

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4 November 2017

White IN

5

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4 November 2017

Gant TW

6

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4 November 2017

language of work or name

English

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publication date

1 July 2000

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4 November 2017

published in

Biochemical Pharmacology

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4 November 2017

volume

60

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4 November 2017

issue

2

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4 November 2017

page(s)

233-239

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Overview from the International Conference on Long-Term Tamoxifen Therapy for Breast Cancer

4 November 2017

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Re: second cancers after adjuvant tamoxifen therapy for breast cancer

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Tamoxifen-DNA adducts detected in the endometrium of women treated with tamoxifen.

7 January 2021

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The metabolism of tamoxifen (I.C.I. 46,474). I. In laboratory animals.

7 January 2021

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Alpha-hydroxytamoxifen, a genotoxic metabolite of tamoxifen in the rat: identification and quantification in vivo and in vitro

7 January 2021

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Distinct P-glycoprotein precursors are overproduced in independently isolated drug-resistant cell lines

7 January 2021

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Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine

7 January 2021

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Multidrug resistance after retroviral transfer of the human MDR1 gene correlates with P-glycoprotein density in the plasma membrane and is not affected by cytotoxic selection

7 January 2021

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The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues

7 January 2021

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Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

7 January 2021

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Altered pharmacokinetics of vinblastine in Mdr1a P-glycoprotein-deficient Mice

7 January 2021

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Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins

7 January 2021

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Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

7 January 2021

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Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

7 January 2021

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P-glycoprotein induction in rat liver epithelial cells in response to acute 3-methylcholanthrene treatment

7 January 2021

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Regulation of 2-acetylaminofluorene-and 3-methylcholanthrene-mediated induction of multidrug resistance and cytochrome P450IA gene family expression in primary hepatocyte cultures and rat liver

7 January 2021

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Cloning and characterization of a member of the rat multidrug resistance (mdr) gene family

7 January 2021

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Carcinogen-induced mdr overexpression is associated with xenobiotic resistance in rat preneoplastic liver nodules and hepatocellular carcinomas

7 January 2021

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Induction of multidrug resistance gene expression during cholestasis in rats and nonhuman primates.

7 January 2021

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In Vivo Induction of Liver P-Glycoprotein Expression by Xenobiotics in Monkeys

7 January 2021

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Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.

7 January 2021

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DNA damage as assessed by 32P-postlabelling in three rat strains exposed to dietary tamoxifen: the relationship between cell proliferation and liver tumour formation

7 January 2021

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Use of internally controlled reverse transcriptase-polymerase chain reaction for absolute quantitation of individual multidrug resistant gene transcripts in tissue samples

7 January 2021

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Interaction of tamoxifen with the multidrug resistance P-glycoprotein.

7 January 2021

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Reversal of P-glycoprotein-mediated multidrug resistance by pure anti-oestrogens and novel tamoxifen derivatives

7 January 2021

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Antiestrogens and steroid hormones: substrates of the human P-glycoprotein.

7 January 2021

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Modulation of doxorubicin-toxicity by tamoxifen in multidrug-resistant tumor cells in vitro and in vivo

7 January 2021

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Selective reversal of vinblastine resistance in multidrug-resistant cell lines by tamoxifen, toremifene and their metabolites.

7 January 2021

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The multidrug-resistance-reverser verapamil interferes with cellular P-glycoprotein-mediated pumping of daunorubicin as a non-competing substrate

7 January 2021

1 reference

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Metabolism of tamoxifen by isolated rat hepatocytes. Identification of the glucuronide of 4-hydroxytamoxifen

7 January 2021

1 reference

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Species differences in the covalent binding of [14C]tamoxifen to liver microsomes and the forms of cytochrome P450 involved

7 January 2021

1 reference

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ATP-dependent 17 beta-estradiol 17-(beta-D-glucuronide) transport by multidrug resistance protein (MRP). Inhibition by cholestatic steroids

7 January 2021

1 reference

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Induction of hepatic mrp2 (cmrp/cmoat) gene expression in nonhuman primates treated with rifampicin or tamoxifen

7 January 2021

1 reference

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cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats

7 January 2021

1 reference

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High-dose oral tamoxifen, a potential multidrug-resistance-reversal agent: phase I trial in combination with vinblastine

7 January 2021

1 reference

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10.1016/S0006-2952(00)00326-9

7 January 2021

Identifiers

DOI

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4 November 2017

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